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The map label for this gene is bcpA [H]

Identifier: 145295202

GI number: 145295202

Start: 1252903

End: 1253667

Strand: Direct

Name: bcpA [H]

Synonym: cgR_1143

Alternate gene names: 145295202

Gene position: 1252903-1253667 (Clockwise)

Preceding gene: 145295201

Following gene: 145295203

Centisome position: 37.8

GC content: 58.04

Gene sequence:

>765_bases
ATGTCTGACCTGAAGTCACTTGCCACGAAATTTGCTAGCGATCATGAATCCGGAAAGCTGCTGGTCCTGCCTACCGTCTG
GGATACCTGGAGCGCGGGGCTCGTAGAAGAAGCAGGATTTAGTGGTCTGACCATTGGTAGCCACCCAGTCGCGGATGCGA
CGGGAAGCTCCGATGGTGAAAACATGAATTTTGCAGATTATATGGCGGTGGTCAAGAAGATCACCTCGGCGGTATCCATC
CCCGTAAGCGTTGATGTGGAATCCGGTTATGGTCTCTCACCTGCGGATTTGATCGCACAGATTTTGGAAGCTGGCGCAGT
GGGCATCAATGTGGAAGATGTTGTGCACAGCGAGGGTAAGCGTGTTCGTGAGGCGCAGGAGCACGCTGATTACATCGCTG
CGGCACGTCAAACTGCCGATGTGGCAGGTGTAGATGTGGTGATCAACGGTCGCACGGATGCCGTCAAACTTGGTGCAGAC
GTTTTTGAAGATCCGATGGTGGAGGCCATCAAGCGCATCAAGCTCATGGAACAGGCAGGCGCGCGTTCGGTGTACCCCGT
GGGTCTGAGCACCGCCGAGCAGGTTGAGCGCCTGGTGGACGCTGTGTCAGTGCCGGTCAACGTCACCGCGCACCCGGTTG
ATGGGCACGGCGCAGGCGATCTGGCCACCCTCGCAGGCCTTGGTGTGCGCCGCGTGACCTTCGGTCCGCTCTGGCAAAAA
TGGCTGGCTGCCACCTCGGCGCAGCAGCTAAAGGGCTGGGCTTAA

Upstream 100 bases:

>100_bases
TTGGCCACTTGTTTGAGTAGGCTGGCGGGCAGGTGCTTGAAATACTCTGATTAGTTCCAAGCAAATTAGCACAACTTCAC
ACTTTATTTAGGAGCATGTT

Downstream 100 bases:

>100_bases
ATTGCTTGTCGACGCCTAGTGCCACAATGGAGACATGACCGAAACACTTGTGGTGAATGGCCTTGCAGGCGGCTATGGGC
ACCGCACATTATTTAACGAT

Product: hypothetical protein

Products: NA

Alternate protein names: Carboxyphosphonoenolpyruvate phosphonomutase; CPEP phosphonomutase [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGENMNFADYMAVVKKITSAVSI
PVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGKRVREAQEHADYIAAARQTADVAGVDVVINGRTDAVKLGAD
VFEDPMVEAIKRIKLMEQAGARSVYPVGLSTAEQVERLVDAVSVPVNVTAHPVDGHGAGDLATLAGLGVRRVTFGPLWQK
WLAATSAQQLKGWA

Sequences:

>Translated_254_residues
MSDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGENMNFADYMAVVKKITSAVSI
PVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGKRVREAQEHADYIAAARQTADVAGVDVVINGRTDAVKLGAD
VFEDPMVEAIKRIKLMEQAGARSVYPVGLSTAEQVERLVDAVSVPVNVTAHPVDGHGAGDLATLAGLGVRRVTFGPLWQK
WLAATSAQQLKGWA
>Mature_253_residues
SDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGENMNFADYMAVVKKITSAVSIP
VSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGKRVREAQEHADYIAAARQTADVAGVDVVINGRTDAVKLGADV
FEDPMVEAIKRIKLMEQAGARSVYPVGLSTAEQVERLVDAVSVPVNVTAHPVDGHGAGDLATLAGLGVRRVTFGPLWQKW
LAATSAQQLKGWA

Specific function: Catalyzes the formation of an unusual C-P bond that is involved in the biosynthesis of the antibiotic bialaphos (BA). Catalyzes the rearrangement of the carboxyphosphono group of CPEP to form the C-P bond of phosphinopyruvate [H]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isocitrate lyase/PEP mutase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012697
- InterPro:   IPR000918
- InterPro:   IPR018523
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00463 ICL [H]

EC number: =2.7.8.23 [H]

Molecular weight: Translated: 26602; Mature: 26471

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGE
CCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
NMNFADYMAVVKKITSAVSIPVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGK
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCHH
RVREAQEHADYIAAARQTADVAGVDVVINGRTDAVKLGADVFEDPMVEAIKRIKLMEQAG
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCC
ARSVYPVGLSTAEQVERLVDAVSVPVNVTAHPVDGHGAGDLATLAGLGVRRVTFGPLWQK
CCCEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHH
WLAATSAQQLKGWA
HHHHHHHHHHCCCC
>Mature Secondary Structure 
SDLKSLATKFASDHESGKLLVLPTVWDTWSAGLVEEAGFSGLTIGSHPVADATGSSDGE
CHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCC
NMNFADYMAVVKKITSAVSIPVSVDVESGYGLSPADLIAQILEAGAVGINVEDVVHSEGK
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCHH
RVREAQEHADYIAAARQTADVAGVDVVINGRTDAVKLGADVFEDPMVEAIKRIKLMEQAG
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCC
ARSVYPVGLSTAEQVERLVDAVSVPVNVTAHPVDGHGAGDLATLAGLGVRRVTFGPLWQK
CCCEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHH
WLAATSAQQLKGWA
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2160937; 1320191; 1330557; 3611020 [H]