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The map label for this gene is ychM [C]

Identifier: 145295195

GI number: 145295195

Start: 1245684

End: 1247423

Strand: Direct

Name: ychM [C]

Synonym: cgR_1137

Alternate gene names: 145295195

Gene position: 1245684-1247423 (Clockwise)

Preceding gene: 145295193

Following gene: 145295197

Centisome position: 37.59

GC content: 51.44

Gene sequence:

>1740_bases
ATGAGTATTAAGTGGGCTCGCTTTGTACCTGGGATTACCGCGATGCGGGGTTATCAACGATCCTGGTTGAAAGGTGATGT
CATCGCGGGCATAACCGTGGCTGCATACTTGGTTCCACAAGTCATGGCTTATGCCGTCATTGCGGGGTTGCCAGCTGTCG
TTGGTCTGTGGGGAGTTCTGGCTCCCATGGCGCTGTACTTTTTCTTGGGCACGTCTCGAAATCTCTCGGTTGGTCCTGAA
TCAACCACCGCTCTGATGACGGCTGCAGGTGTGGGAGCTTTAGTCGGGGCAGCTGGCGGGCCTGAACGATACGCAGAAGT
AGCAGCACTATTGGCTATTGCAGTGGGCATTGTATGCGCTGTTGGTTTTATTGGCCGATTGGGCTTTCTTACCAGGCTAT
TATCTCGACCGGTGCTCGTTGGATATTTGATCGGTATTGCAGTCTTGATGATCGTCAGTCAGCTGTCCAAAGTCACCCAG
GTGGATGTGGAGAGCGGTCAGACGTGGCAGGAAATAATATCGTTTATCAAAGTAGCCGGCCAGGCACATATTCCTACAGT
GATTTTGGCAGTCGTGGTGTTGAGCTTGCTGTATCTGGCAAATTGGTTGACGCCTAAATTTCCCAGCACACTCATGGTTC
TTCTGCTTTCAGCAGCCGCGGTGGCGTTTTTTCATCTGGATAGGTTTGGTCTTGAGGTCATTGGTGAGGTGCCCCGTGGC
CTGCCTCAACCAAGTATTCCCTCGATTGGCGATCTAGAAATTTGGTCATTGTTGCCCTATGCCGTCGGTATTGCCATCGT
TGGTTTTTCAGACAATGTGTTGACTGCTCGTGCATTCGCATCGGGAAAAGATGAGGTGATTGATTCTAACCAGGAGCTGC
TCGCACTGGGAACCGCGAACCTGGCGAATGGGTTCTTCCAGGGATTTCCTGTGTCTTCGAGTGGCTCAAGGACCGTTCTT
GGCGACACCGCAGGTGCCCGCACTCAGGTGCATTCACTAGTCGTGATTTCTTTAGTGATCATGGTGCTAATGTTCGCTGG
TCCCGTGTTGGAGTCTTTCCCAGATGCAGCGCTTGGTGCCTTAGTTATCTATGCAGCAACGCAGTTGATTGATATCGCAG
AGATCAAAAGGATCGCACGTTTCCGCAAAAGTGAGCTGATTATTACAGCGGCTACAGCTGCATCTGTTGTGGCTTTTGGC
GTGCTCGCGGGCATCGGAGTTGCGGTCGCATTATCCATTCTGGACCTCATCAGACGCATTACCCGACCTTATGCAGATGT
CCTAGGATATACGCCGGGCATGGCTGGAATGCACAGCTTGGAGGATTATCCTGAATCCACGGCAGTCGAGGGGCTTGTGG
TGTTTCGGTACGATTCTCCACTGTTTTTTGCTAACGCTGATGATTTTTCCAAGCGTGCCATCGAAGCGGTTGATGAGGCG
ACTCAACCAGTGCACTGGTTCTTGCTGAATGCTGAAGCGAATACGGAAGTTGATCTCACCGCTGTCGATGCCATGGAAGC
ACTTCGCAAAACCCTCGAAGAAAGAGGCATTCGATTTGCGATGGCCCGAGTGAAACAAGATTTACGCCGCAGCCTCGAGC
CTACGGGTTTCATTAAATCTGTGGGAGCGGAGTACATTTTCGCCACGCTTCCCACTGCTGTTAAAGGTTATTCCGTGGAG
TTTCGCGATCGTTTTGGCACTGACCCGGATGGCGTTCCGAAAGAAATATTGGAGCTTTAA

Upstream 100 bases:

>100_bases
AATCCTTGTTTCAATTGCCCTGGGAGTGGCTGTTTACCCTGGTACTAGCAAAACCCCTTAAAGAGCCTTTTGGTGCCGCG
ATCCGAGTACTTTTAAAAGC

Downstream 100 bases:

>100_bases
ACTGCGTCGAGGTGGACTGAATCGCGACCTATTGGTGCAGTTCCATTAAAACTATAAAGAGAAAAGGCCTACAGGCGCAT
GCGTCCTATAGACCTTTCCA

Product: hypothetical protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSIKWARFVPGITAMRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVLAPMALYFFLGTSRNLSVGPE
STTALMTAAGVGALVGAAGGPERYAEVAALLAIAVGIVCAVGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQ
VDVESGQTWQEIISFIKVAGQAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVAFFHLDRFGLEVIGEVPRG
LPQPSIPSIGDLEIWSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTANLANGFFQGFPVSSSGSRTVL
GDTAGARTQVHSLVVISLVIMVLMFAGPVLESFPDAALGALVIYAATQLIDIAEIKRIARFRKSELIITAATAASVVAFG
VLAGIGVAVALSILDLIRRITRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEA
TQPVHWFLLNAEANTEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPTGFIKSVGAEYIFATLPTAVKGYSVE
FRDRFGTDPDGVPKEILEL

Sequences:

>Translated_579_residues
MSIKWARFVPGITAMRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVLAPMALYFFLGTSRNLSVGPE
STTALMTAAGVGALVGAAGGPERYAEVAALLAIAVGIVCAVGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQ
VDVESGQTWQEIISFIKVAGQAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVAFFHLDRFGLEVIGEVPRG
LPQPSIPSIGDLEIWSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTANLANGFFQGFPVSSSGSRTVL
GDTAGARTQVHSLVVISLVIMVLMFAGPVLESFPDAALGALVIYAATQLIDIAEIKRIARFRKSELIITAATAASVVAFG
VLAGIGVAVALSILDLIRRITRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEA
TQPVHWFLLNAEANTEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPTGFIKSVGAEYIFATLPTAVKGYSVE
FRDRFGTDPDGVPKEILEL
>Mature_578_residues
SIKWARFVPGITAMRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVLAPMALYFFLGTSRNLSVGPES
TTALMTAAGVGALVGAAGGPERYAEVAALLAIAVGIVCAVGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQV
DVESGQTWQEIISFIKVAGQAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVAFFHLDRFGLEVIGEVPRGL
PQPSIPSIGDLEIWSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTANLANGFFQGFPVSSSGSRTVLG
DTAGARTQVHSLVVISLVIMVLMFAGPVLESFPDAALGALVIYAATQLIDIAEIKRIARFRKSELIITAATAASVVAFGV
LAGIGVAVALSILDLIRRITRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEAT
QPVHWFLLNAEANTEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPTGFIKSVGAEYIFATLPTAVKGYSVEF
RDRFGTDPDGVPKEILEL

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=494, Percent_Identity=26.9230769230769, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI39752683, Length=494, Percent_Identity=26.9230769230769, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI94721259, Length=476, Percent_Identity=30.4621848739496, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI94721257, Length=476, Percent_Identity=30.4621848739496, Blast_Score=174, Evalue=3e-43,
Organism=Homo sapiens, GI94721255, Length=476, Percent_Identity=30.4621848739496, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI94721253, Length=476, Percent_Identity=30.4621848739496, Blast_Score=173, Evalue=4e-43,
Organism=Homo sapiens, GI47131207, Length=513, Percent_Identity=28.8499025341131, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI20336272, Length=513, Percent_Identity=28.8499025341131, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI4557535, Length=495, Percent_Identity=27.6767676767677, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI4505697, Length=499, Percent_Identity=26.6533066132265, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI269784651, Length=493, Percent_Identity=25.1521298174442, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI45827802, Length=442, Percent_Identity=26.9230769230769, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI16418413, Length=498, Percent_Identity=25.5020080321285, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI217272867, Length=488, Percent_Identity=25.6147540983607, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI100913030, Length=657, Percent_Identity=22.6788432267884, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI262206105, Length=615, Percent_Identity=25.5284552845528, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI262206075, Length=615, Percent_Identity=25.5284552845528, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI262206069, Length=615, Percent_Identity=25.5284552845528, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI262206063, Length=615, Percent_Identity=25.5284552845528, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI20336282, Length=568, Percent_Identity=24.2957746478873, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI16306483, Length=524, Percent_Identity=24.618320610687, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI65506789, Length=367, Percent_Identity=28.3378746594005, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI16418457, Length=526, Percent_Identity=21.1026615969582, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI301601599, Length=526, Percent_Identity=21.1026615969582, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI301601602, Length=213, Percent_Identity=22.5352112676056, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI45827804, Length=262, Percent_Identity=23.2824427480916, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551690, Length=593, Percent_Identity=27.318718381113, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17566848, Length=567, Percent_Identity=27.1604938271605, Blast_Score=178, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI86564196, Length=609, Percent_Identity=24.9589490968801, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17562578, Length=606, Percent_Identity=26.4026402640264, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI86565215, Length=569, Percent_Identity=26.3620386643234, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI86564876, Length=664, Percent_Identity=22.8915662650602, Blast_Score=148, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI193203292, Length=493, Percent_Identity=26.1663286004057, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI86565213, Length=265, Percent_Identity=28.3018867924528, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI86565209, Length=244, Percent_Identity=27.8688524590164, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI86565211, Length=244, Percent_Identity=27.8688524590164, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325260, Length=595, Percent_Identity=24.0336134453782, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323121, Length=470, Percent_Identity=26.5957446808511, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319771, Length=409, Percent_Identity=25.6723716381418, Blast_Score=113, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24649801, Length=442, Percent_Identity=26.6968325791855, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24666186, Length=392, Percent_Identity=29.0816326530612, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI85815873, Length=443, Percent_Identity=26.1851015801354, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24663084, Length=554, Percent_Identity=25.9927797833935, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357695, Length=554, Percent_Identity=25.9927797833935, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24651449, Length=461, Percent_Identity=25.1626898047722, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI21358229, Length=463, Percent_Identity=25.7019438444924, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24647160, Length=444, Percent_Identity=24.0990990990991, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI21355087, Length=441, Percent_Identity=24.2630385487528, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21358633, Length=459, Percent_Identity=26.797385620915, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19922482, Length=557, Percent_Identity=22.6211849192101, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61665; Mature: 61534

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCCCHHHHCC
>Mature Secondary Structure 
SIKWARFVPGITAMRGYQRSWLKGDVIAGITVAAYLVPQVMAYAVIAGLPAVVGLWGVL
CCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APMALYFFLGTSRNLSVGPESTTALMTAAGVGALVGAAGGPERYAEVAALLAIAVGIVCA
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VGFIGRLGFLTRLLSRPVLVGYLIGIAVLMIVSQLSKVTQVDVESGQTWQEIISFIKVAG
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
QAHIPTVILAVVVLSLLYLANWLTPKFPSTLMVLLLSAAAVAFFHLDRFGLEVIGEVPRG
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPQPSIPSIGDLEIWSLLPYAVGIAIVGFSDNVLTARAFASGKDEVIDSNQELLALGTAN
CCCCCCCCCCCHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCHHHHCCCCCEEEECCHH
LANGFFQGFPVSSSGSRTVLGDTAGARTQVHSLVVISLVIMVLMFAGPVLESFPDAALGA
HHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LVIYAATQLIDIAEIKRIARFRKSELIITAATAASVVAFGVLAGIGVAVALSILDLIRRI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRPYADVLGYTPGMAGMHSLEDYPESTAVEGLVVFRYDSPLFFANADDFSKRAIEAVDEA
HHHHHHHHCCCCCCCHHHHHHHCCCCHHHCEEEEEEECCCEEEECCCHHHHHHHHHHHHH
TQPVHWFLLNAEANTEVDLTAVDAMEALRKTLEERGIRFAMARVKQDLRRSLEPTGFIKS
CCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHH
VGAEYIFATLPTAVKGYSVEFRDRFGTDPDGVPKEILEL
HHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]