Click here to switch to the map view.

The map label for this gene is pab [H]

Identifier: 145295145

GI number: 145295145

Start: 1200527

End: 1202389

Strand: Direct

Name: pab [H]

Synonym: cgR_1088

Alternate gene names: 145295145

Gene position: 1200527-1202389 (Clockwise)

Preceding gene: 145295144

Following gene: 145295146

Centisome position: 36.22

GC content: 53.46

Gene sequence:

>1863_bases
ATGCGCGTTTTAATTATTGATAATTATGATTCTTTCACGTTTAATCTCGCCACCTATGTGGAAGAGGTTACGGGTCAGGC
ACCTGTGGTGGTGCCTAATGATCAAGAAATAGATGAGACGCTTTTCGACGCCGTCATCCTCTCACCGGGCCCGGGCCACG
CCGGCGTTGCGGCCGATTTTGGTATCTCTGCAGGCGTCATTGAGCGTGCACGCGTTCCGATTTTGGGTGTGTGTTTAGGC
CACCAGGGCATTGCGTTGGCTCATGACGGTGATGTTGATTTGGCGCCCAGGCCGGTCCACGGTGAGGTTTCGCAGATCAC
CCATGATGGTTCAGGTTTATTTGCAGGCATCCCTGAAACGTTTGAGGCGGTGCGTTATCACTCGATGGTGGCAACCCGCT
TGCCGGAGTCATTGAGAGCTACAGCTACCAGCGATGATGGTTTGATCATGGCATTGGCACATGAAATGCTTCCGCAGTGG
GGTGTGCAATTTCATCCGGAATCTATTGGTGGACAATTCGGCCATCAGATCATTAAGAACTTCCTTAATTTAGCGCGCAC
ATATCGCTGGCAACTCATGGAGAAAACTATTCCGCTCAGCGTTGATTCAGCAGCGGTTTTTGAAACATTCTTTGCCCATT
CCTCCCATGCTTTTTGGCTCGATGATGCCCAAGGAACCAGCTATCTTGGTGATGCCAGCGGTCCTCTCGCACGCACAAAA
ACCCATAATGTCGGCGAGGGGGATTTCTTCACCTGGCTAAAGGAGGATCTCGCCGCCAACTCAGTTGCGCCCGGTCAAGG
TTTTCGTCTTGGCTGGGTTGGTTACGTTGGTTATGAGCTTAAAGCGGAAGCTGGCGCACGGGCTGCACACACTTCGAGTC
TTCCGGATGCGCACCTCATTTTTGCCGATCGCACCATCGCAGTGGAATCGGATCAGGTTCGGTTGCTGGCGTTGGGGGAG
CAAGACGCATGGTTTGAAGAAACCACGGAGAAGCTGCATAATCTTGTCGCCCCGCGGATACCTGCGTCCGGACACCTCGC
TTTGCAGGTTCGAGATTCCAAAGATGGGTATCTCGACAAAATTCGCAGAGCCCAGGAGCTGATTACTCGCGGCGAATCGT
ATGAAATCTGCCTGACCACAAAACTTCAGGGCACCACTGATGCGGCCCCTCTGGCTGCCTATCTAGCACTGCGTGGGGCC
AATCCCACCGCATATGGTGCGTATCTTCAGCTGGGGGATACCTCTATTTTGAGTTCCTCGCCGGAGCGGTTCATCACCAT
TGATTCGGCAGGGCATGTGGAATCAAAGCCCATTAAAGGCACCAGGCCGCGTGGGCGAACAGCGCAAGAAGACCAAGAAA
TCATTGCTGAGCTGCGCAGTAATCCTAAAGATCGTGCAGAAAACTTGATGATCGTAGATTTGGTCCGCAACGACTTAGCC
CGCGGCGCTTTGCCCACCACAGTTAAAACATCCAAGCTTTTCGACGTCGAAACCTACGCCACAGTCCACCAACTTGTCAG
CACCGTCTCTGCAGAGTTGGGGCCACGCAGTCCGATTGAGTGCGTGCGCGCAGCATTCCCCGGTGGTTCGATGACTGGTG
CCCCAAAGCTGCGCACCATGGAGATCATCGATGAGCTGGAGGCAGCTCCTCGCGGTATTTACTCAGGTGGCTTGGGATAT
TTTTCCCTCGACGGCGCAGTTGATCTCTCCATGGTGATCAGAACTCTCGTCATCCAGAACAATCACGTGGAGTACGGAGT
GGGCGGTGCACTTCTTGCTCTGTCTGATCCGGAGGCTGAGTGGGAGGAAATCCGCGTTAAATCACGGCCTCTGCTGAATT
TATTTGGGGTTGAATTCCCATGA

Upstream 100 bases:

>100_bases
TCGTCTAAGCTTTTCTTTGAGTTTTCATATGTAGAAGGCATCGTCGGCTTCGGCCTGGCGGTGCTTTTCTCGTTGTTTTG
TGGTTTTGTCAGAGGATGTC

Downstream 100 bases:

>100_bases
CGTACCTCGTGTGGGACGGCGCAACACTCGTAGAAGGCGCGCTGGAATCAACACCCACAGTTGTTGATTCCTACCTAGCC
AAAGACCACCGCGTGGTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDETLFDAVILSPGPGHAGVAADFGISAGVIERARVPILGVCLG
HQGIALAHDGDVDLAPRPVHGEVSQITHDGSGLFAGIPETFEAVRYHSMVATRLPESLRATATSDDGLIMALAHEMLPQW
GVQFHPESIGGQFGHQIIKNFLNLARTYRWQLMEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLIFADRTIAVESDQVRLLALGE
QDAWFEETTEKLHNLVAPRIPASGHLALQVRDSKDGYLDKIRRAQELITRGESYEICLTTKLQGTTDAAPLAAYLALRGA
NPTAYGAYLQLGDTSILSSSPERFITIDSAGHVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTMEIIDELEAAPRGIYSGGLGY
FSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAEWEEIRVKSRPLLNLFGVEFP

Sequences:

>Translated_620_residues
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDETLFDAVILSPGPGHAGVAADFGISAGVIERARVPILGVCLG
HQGIALAHDGDVDLAPRPVHGEVSQITHDGSGLFAGIPETFEAVRYHSMVATRLPESLRATATSDDGLIMALAHEMLPQW
GVQFHPESIGGQFGHQIIKNFLNLARTYRWQLMEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLIFADRTIAVESDQVRLLALGE
QDAWFEETTEKLHNLVAPRIPASGHLALQVRDSKDGYLDKIRRAQELITRGESYEICLTTKLQGTTDAAPLAAYLALRGA
NPTAYGAYLQLGDTSILSSSPERFITIDSAGHVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTMEIIDELEAAPRGIYSGGLGY
FSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAEWEEIRVKSRPLLNLFGVEFP
>Mature_620_residues
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDETLFDAVILSPGPGHAGVAADFGISAGVIERARVPILGVCLG
HQGIALAHDGDVDLAPRPVHGEVSQITHDGSGLFAGIPETFEAVRYHSMVATRLPESLRATATSDDGLIMALAHEMLPQW
GVQFHPESIGGQFGHQIIKNFLNLARTYRWQLMEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLIFADRTIAVESDQVRLLALGE
QDAWFEETTEKLHNLVAPRIPASGHLALQVRDSKDGYLDKIRRAQELITRGESYEICLTTKLQGTTDAAPLAAYLALRGA
NPTAYGAYLQLGDTSILSSSPERFITIDSAGHVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTMEIIDELEAAPRGIYSGGLGY
FSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAEWEEIRVKSRPLLNLFGVEFP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=361, Percent_Identity=37.6731301939058, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1787518, Length=363, Percent_Identity=31.129476584022, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=43.9153439153439, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787517, Length=193, Percent_Identity=37.3056994818653, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87082077, Length=269, Percent_Identity=25.6505576208178, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786809, Length=263, Percent_Identity=25.0950570342205, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=392, Percent_Identity=30.6122448979592, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=391, Percent_Identity=31.4578005115089, Blast_Score=156, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=191, Percent_Identity=39.7905759162304, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323873, Length=204, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67175; Mature: 67175

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDETLFDAVILSPGPGHAGVAADF
CEEEEEECCCCEEEHHHHHHHHHCCCCCEEECCCCHHHHHHHHEEEECCCCCCCCCEECC
GISAGVIERARVPILGVCLGHQGIALAHDGDVDLAPRPVHGEVSQITHDGSGLFAGIPET
CCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEEECCCCEEECCHHH
FEAVRYHSMVATRLPESLRATATSDDGLIMALAHEMLPQWGVQFHPESIGGQFGHQIIKN
HHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCEECCHHHCHHHHHHHHHH
FLNLARTYRWQLMEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLI
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECEEEECCCCCCHHCCCCCCCCEEE
FADRTIAVESDQVRLLALGEQDAWFEETTEKLHNLVAPRIPASGHLALQVRDSKDGYLDK
EECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHH
IRRAQELITRGESYEICLTTKLQGTTDAAPLAAYLALRGANPTAYGAYLQLGDTSILSSS
HHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHCCC
PERFITIDSAGHVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
CCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEEEEHHHHHHH
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTM
CCCCCCCEECCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHH
EIIDELEAAPRGIYSGGLGYFSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAE
HHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEECCCEEEEEECCCCCC
WEEIRVKSRPLLNLFGVEFP
HHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLIIDNYDSFTFNLATYVEEVTGQAPVVVPNDQEIDETLFDAVILSPGPGHAGVAADF
CEEEEEECCCCEEEHHHHHHHHHCCCCCEEECCCCHHHHHHHHEEEECCCCCCCCCEECC
GISAGVIERARVPILGVCLGHQGIALAHDGDVDLAPRPVHGEVSQITHDGSGLFAGIPET
CCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHEEECCCCEEECCHHH
FEAVRYHSMVATRLPESLRATATSDDGLIMALAHEMLPQWGVQFHPESIGGQFGHQIIKN
HHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHCCCEECCHHHCHHHHHHHHHH
FLNLARTYRWQLMEKTIPLSVDSAAVFETFFAHSSHAFWLDDAQGTSYLGDASGPLARTK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
THNVGEGDFFTWLKEDLAANSVAPGQGFRLGWVGYVGYELKAEAGARAAHTSSLPDAHLI
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEEEECEEEECCCCCCHHCCCCCCCCEEE
FADRTIAVESDQVRLLALGEQDAWFEETTEKLHNLVAPRIPASGHLALQVRDSKDGYLDK
EECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHH
IRRAQELITRGESYEICLTTKLQGTTDAAPLAAYLALRGANPTAYGAYLQLGDTSILSSS
HHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCHHHCCC
PERFITIDSAGHVESKPIKGTRPRGRTAQEDQEIIAELRSNPKDRAENLMIVDLVRNDLA
CCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCEEEEEHHHHHHH
RGALPTTVKTSKLFDVETYATVHQLVSTVSAELGPRSPIECVRAAFPGGSMTGAPKLRTM
CCCCCCCEECCEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHH
EIIDELEAAPRGIYSGGLGYFSLDGAVDLSMVIRTLVIQNNHVEYGVGGALLALSDPEAE
HHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEECCCEEEEEECCCCCC
WEEIRVKSRPLLNLFGVEFP
HHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]