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The map label for this gene is ripA [H]

Identifier: 145295133

GI number: 145295133

Start: 1189451

End: 1190446

Strand: Direct

Name: ripA [H]

Synonym: cgR_1076

Alternate gene names: 145295133

Gene position: 1189451-1190446 (Clockwise)

Preceding gene: 145295132

Following gene: 145295134

Centisome position: 35.89

GC content: 57.43

Gene sequence:

>996_bases
ATGAGTTCTGCCAGCTTGTTGTGGTGCCATTCCGGTGTGTCAACAGTTCGTTTTGGCGAGAGAATTTTCACTCTCGTCGC
AGGTGACCTTCTGTTCGCGCCAGAGGAAGTTCAGGTTACCGATGATTCTCAGGGGCTTGTTCTCAACATCCGCTTTGAGA
CCCTAAACATCGCCGGGTCTGCGCGTCGCATCCACCTGGGTCACGTGTGGAATGACCGTCTGACATTTGAATACAGTCGC
TCGCTGTTCGGGAAAGGGACACTTTCATCGGATATCGCGCGCCTGTTCACCGACCGCGTGCCCACCCCGCCGCTGCCAGC
TCCTCGAAAGGCGCGCGCCGTGGCTCAGGTGCTGGTGTCCAATCCTGCGGATCAGACTAGTTTGGAAGAATTCGCGGAGA
TCCAGGGCGTTTCAGCGCGTACCTTGCAGCGCCAGTTCCTCAAATCCACGGGCTATTCCTTCAGTGAATGGCGTGCCGCG
CAACGCGTCTGTGTCGCCGCGAGCCTGCTGGCCCACGACTTCAGCATTTCAGTGGTTGCGAACCTAGTCGGGTTTGCCGC
GACCAGCAGCTTGACCAGAGCTTTTCGACGCCACACCGGTGCAACTCCGTCCACCTTTACCACTGGACAGATCGGAATGG
GCTCCGCAGGCCACCCGCCACGTATCCCAGCAACCACCACGTTTGCAGAAGCACACCAGGACCAGCAGCTGTGGATCTAC
AGTGGAACCGCAACCGTCACCACCCCCGGATACTGCCGATTCATGGGCCAAGGTGACATGGTGACTATCCCTGCCGGCAC
CCAAACACGCATTGATGTGGCAGCAGGATCCATCGCGTTCCCAGTTCCAGTTGGACTGGACGAATGGGGAATGGACCTAA
CCCGTGTCGTGGCTGTTAATAACCAGCAGCCAAAGCCACTAACCATTTTGGAGCAGTCCGAATGGTCCAAGCTCAGCGAG
GAGCTTTTGAACACTCCAGTGCCTGTACAAATGTGA

Upstream 100 bases:

>100_bases
AGTCTCTTGCAATACTTCGCATCTGGAATGTAACATCATTTCGAAGATATGAGGTTAGCGTAACCTACATTGTGAAATTT
GCTTGTAGTGAGGATGAGAT

Downstream 100 bases:

>100_bases
AGGTAGTAAAGGTGTGAAAATAGTTCCTCACGTGGGGAACTATACTGATCCTTGATGCGTTAACTTGATTGTACGACGAA
AAATCAACTGAAAGGATCGG

Product: AraC-type DNA-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEVQVTDDSQGLVLNIRFETLNIAGSARRIHLGHVWNDRLTFEYSR
SLFGKGTLSSDIARLFTDRVPTPPLPAPRKARAVAQVLVSNPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAA
QRVCVAASLLAHDFSISVVANLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIY
SGTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVNNQQPKPLTILEQSEWSKLSE
ELLNTPVPVQM

Sequences:

>Translated_331_residues
MSSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEVQVTDDSQGLVLNIRFETLNIAGSARRIHLGHVWNDRLTFEYSR
SLFGKGTLSSDIARLFTDRVPTPPLPAPRKARAVAQVLVSNPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAA
QRVCVAASLLAHDFSISVVANLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIY
SGTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVNNQQPKPLTILEQSEWSKLSE
ELLNTPVPVQM
>Mature_330_residues
SSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEVQVTDDSQGLVLNIRFETLNIAGSARRIHLGHVWNDRLTFEYSRS
LFGKGTLSSDIARLFTDRVPTPPLPAPRKARAVAQVLVSNPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAAQ
RVCVAASLLAHDFSISVVANLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIYS
GTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVNNQQPKPLTILEQSEWSKLSEE
LLNTPVPVQM

Specific function: Under iron limitation, represses the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and kat

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35951; Mature: 35820

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEVQVTDDSQGLVLNIRFETLNIAGS
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEEEEEEEEECCC
ARRIHLGHVWNDRLTFEYSRSLFGKGTLSSDIARLFTDRVPTPPLPAPRKARAVAQVLVS
CEEEEEEEEECCCEEEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHC
NPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAAQRVCVAASLLAHDFSISVVA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHH
NLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIY
HHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEE
SGTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVN
ECCEEEECCCEEEEECCCCEEEECCCCCEEEEEECCCEEECCCCCCCHHCCCEEEEEEEC
NQQPKPLTILEQSEWSKLSEELLNTPVPVQM
CCCCCCEEEEECHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEVQVTDDSQGLVLNIRFETLNIAGS
CCCCEEEEECCCCHHHHHHHHHHHHHHHHEECCCEEEEECCCCCEEEEEEEEEEEECCC
ARRIHLGHVWNDRLTFEYSRSLFGKGTLSSDIARLFTDRVPTPPLPAPRKARAVAQVLVS
CEEEEEEEEECCCEEEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHC
NPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAAQRVCVAASLLAHDFSISVVA
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHH
NLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIY
HHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEE
SGTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVN
ECCEEEECCCEEEEECCCCEEEECCCCCEEEEEECCCEEECCCCCCCHHCCCEEEEEEEC
NQQPKPLTILEQSEWSKLSEELLNTPVPVQM
CCCCCCEEEEECHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]