Click here to switch to the map view.

The map label for this gene is lysI [H]

Identifier: 145295122

GI number: 145295122

Start: 1180340

End: 1181845

Strand: Reverse

Name: lysI [H]

Synonym: cgR_1065

Alternate gene names: 145295122

Gene position: 1181845-1180340 (Counterclockwise)

Preceding gene: 145295125

Following gene: 145295121

Centisome position: 35.66

GC content: 52.79

Gene sequence:

>1506_bases
GTGAATACTCAAACAGATTCTGCGGGGTATCAAGGTGCAGCGGCCACAAGTCGTACTGTATCTATTAGAACCCTCATCGC
GCTGATCATCGGATCGACCGTCGGCGCTGGAATTTTCTCCATCCCTCAAAACATCGGCTCAGTCGCAGGTCCCGGCGCGA
TGCTCATCGGCTGGCTGATCGCCGGTGTGGGCATGTTGTCCGTAGCGTTCGTGTTCCACGTTCTTGCCCGCCGTAAACCT
CACCTCGATTCTGGCGTCTACGCATATGCGCGTGTTGGATTGGGCGATTATGTAGGTTTCTCCTCCGCTTGGGGTTATTG
GCTGGGTTCAGTCATCGCCCAAGTTGGCTACGCAACGTTATTTTTCTCCACGTTGGGCCACTACGTACCGCTGTTTTCCC
AAGATCATCCATTTGTGTCAGCGTTGGCAGTTAGCGCTTTGACCTGGCTGGTGTTTGGAGTTGTTTCCCGAGGAATTAGC
CAAGCTGCTTTCTTGACAACGGTTACCACCGTGGCCAAAATTCTGCCTCTGTTGTGCTTCATCATCCTTGTTGCATTCTT
GGGCTTTAGCTGGGAGAAGTTCACTGTTGATTTATGGGCGCGTGATGGTGGCGTGGGCAGCATTTTTGATCAGGTGCGCG
GCATCATGGTGTACACCGTGTGGGTGTTCATCGGTATCGAAGGTGCATCGGTATATTCCCGCCAGGCACGCTCACGCAGT
GATGTCAGCCGAGCTACCGTGATTGGTTTTGTGGCTGTTCTCCTTTTGCTGGTGTCGATTTCTTCGCTGAGCTTCGGTGT
ACTGACCCAACAAGAGCTCGCTGCGTTACCAGATAATTCCATGGCGTCGGTGCTCGAAGCTGTTGTTGGTCCATGGGGTG
CCGCATTGATTTCGTTGGGTCTGTGCCTTTCGGTTCTTGGGGCCTATGTGTCCTGGCAGATGCTCTGCGCAGAACCACTG
GCGTTGATGGCAATGGATGGCCTCATTCCAAGCAAAATCGGGGCCATCAACAGCCGCGGTGCTGCCTGGATGGCTCAGCT
GATCTCCACCATCGTGATTCAGATTTTCATCATCATTTTCTTCCTCAACGAGACCACCTACGTCTCCATGGTGCAATTGG
CTACCAACCTATACTTAGTGCCTTACCTGTTCTCTGCCTTTTATCTGGTCATGCTGGCAACACGTGGAAAAGGAATCACC
CACCCACATGCCGGCACACGTTTTGATGATTCCGGTCCAGTTATTTCTCGCCGTGAAAACCGCAAACACCTCATCGTCGG
TGTGGTGGCAACCGTATATTCAGTGTGGTTGTTTTATGCTGCAGAACCGCAGTTTGTCCTCTTCGGAGCCATGGCAATGC
TTCCCGGCTTGATCCCCTATGTGTGGACCAGGCTTTATCGAGGCGAGCGAGTGTTTAACCGCTTTGAAATCGGCGTGGTT
GTTGTCCTGGTCGTTGCTGCCAGTGCGGGCGTTATTGGTTTGGTCAACGGATCACTATCGCTTTAA

Upstream 100 bases:

>100_bases
GTTCTCCAGCCTTTCTAAACAATTCATCTGCACTTGATTAATTGGTCCCAAGATTACGCGAAGTTTAGCGACTTCGCCGT
ACGTCAACTACGTTAAATGA

Downstream 100 bases:

>100_bases
GCAATCGCTTTAAGCACCGGAACCTTCCTGCTAGTTCACCAAGATTTTTAAGTTTTACCGCAATTTCTTGAGAGATTTGG
GAGGATAATGGCGGTGTGAA

Product: hypothetical protein

Products: NA

Alternate protein names: L-lysine permease [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MNTQTDSAGYQGAAATSRTVSIRTLIALIIGSTVGAGIFSIPQNIGSVAGPGAMLIGWLIAGVGMLSVAFVFHVLARRKP
HLDSGVYAYARVGLGDYVGFSSAWGYWLGSVIAQVGYATLFFSTLGHYVPLFSQDHPFVSALAVSALTWLVFGVVSRGIS
QAAFLTTVTTVAKILPLLCFIILVAFLGFSWEKFTVDLWARDGGVGSIFDQVRGIMVYTVWVFIGIEGASVYSRQARSRS
DVSRATVIGFVAVLLLLVSISSLSFGVLTQQELAALPDNSMASVLEAVVGPWGAALISLGLCLSVLGAYVSWQMLCAEPL
ALMAMDGLIPSKIGAINSRGAAWMAQLISTIVIQIFIIIFFLNETTYVSMVQLATNLYLVPYLFSAFYLVMLATRGKGIT
HPHAGTRFDDSGPVISRRENRKHLIVGVVATVYSVWLFYAAEPQFVLFGAMAMLPGLIPYVWTRLYRGERVFNRFEIGVV
VVLVVAASAGVIGLVNGSLSL

Sequences:

>Translated_501_residues
MNTQTDSAGYQGAAATSRTVSIRTLIALIIGSTVGAGIFSIPQNIGSVAGPGAMLIGWLIAGVGMLSVAFVFHVLARRKP
HLDSGVYAYARVGLGDYVGFSSAWGYWLGSVIAQVGYATLFFSTLGHYVPLFSQDHPFVSALAVSALTWLVFGVVSRGIS
QAAFLTTVTTVAKILPLLCFIILVAFLGFSWEKFTVDLWARDGGVGSIFDQVRGIMVYTVWVFIGIEGASVYSRQARSRS
DVSRATVIGFVAVLLLLVSISSLSFGVLTQQELAALPDNSMASVLEAVVGPWGAALISLGLCLSVLGAYVSWQMLCAEPL
ALMAMDGLIPSKIGAINSRGAAWMAQLISTIVIQIFIIIFFLNETTYVSMVQLATNLYLVPYLFSAFYLVMLATRGKGIT
HPHAGTRFDDSGPVISRRENRKHLIVGVVATVYSVWLFYAAEPQFVLFGAMAMLPGLIPYVWTRLYRGERVFNRFEIGVV
VVLVVAASAGVIGLVNGSLSL
>Mature_501_residues
MNTQTDSAGYQGAAATSRTVSIRTLIALIIGSTVGAGIFSIPQNIGSVAGPGAMLIGWLIAGVGMLSVAFVFHVLARRKP
HLDSGVYAYARVGLGDYVGFSSAWGYWLGSVIAQVGYATLFFSTLGHYVPLFSQDHPFVSALAVSALTWLVFGVVSRGIS
QAAFLTTVTTVAKILPLLCFIILVAFLGFSWEKFTVDLWARDGGVGSIFDQVRGIMVYTVWVFIGIEGASVYSRQARSRS
DVSRATVIGFVAVLLLLVSISSLSFGVLTQQELAALPDNSMASVLEAVVGPWGAALISLGLCLSVLGAYVSWQMLCAEPL
ALMAMDGLIPSKIGAINSRGAAWMAQLISTIVIQIFIIIFFLNETTYVSMVQLATNLYLVPYLFSAFYLVMLATRGKGIT
HPHAGTRFDDSGPVISRRENRKHLIVGVVATVYSVWLFYAAEPQFVLFGAMAMLPGLIPYVWTRLYRGERVFNRFEIGVV
VVLVVAASAGVIGLVNGSLSL

Specific function: Permease that is involved in the transport across the membrane of lysine [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=477, Percent_Identity=35.6394129979036, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI2367353, Length=432, Percent_Identity=24.537037037037, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790575, Length=394, Percent_Identity=22.8426395939086, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53705; Mature: 53705

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure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HHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1667221; 12948626 [H]