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The map label for this gene is ggt [H]

Identifier: 145295113

GI number: 145295113

Start: 1165012

End: 1166985

Strand: Reverse

Name: ggt [H]

Synonym: cgR_1056

Alternate gene names: 145295113

Gene position: 1166985-1165012 (Counterclockwise)

Preceding gene: 145295115

Following gene: 145295108

Centisome position: 35.21

GC content: 54.2

Gene sequence:

>1974_bases
ATGAAAGTGACCCAAAGCACATTCCTTAAATCGGTAGCTGTGTTCACTGTCGCAGCTTTAACCCTGACCATCTCTTCGTG
TTCCAGCGGTGAAGACACCTCCGCAAGCTCCACGGATGCTGAAAACTCCTCAACCCAAGCAGCAGCGTCTCCCCCACTTG
CGCCTTGTGAACTTCCCGCCGACGCTTCTGCTGAAGAGGAAGTAGAAGGCACTCACACAGGTGAAGATATTTCTGTTGCC
CCGGAAATCGGTACCGGCTACCGCGAGGGCATGACCCCCGTTCAAACCCAAGGTTATGCGGTGGCAACTGCAAACCCCAT
TGCTTCTGAAGCAGCCTGCGCGGTGTTAAGAGAAGGCGGCACTGCCGCTGATGCTCTTGTCACCGCGCAGTTTGTTTTGG
GACTGACGGAACCGCAGTCGTCTGGCCTTGGTGGCGGCGGATACATTCTGTACTACGACGCCGAAGCCAATGCGGTGACA
GCCATTGATGGCCGTGAAACAGCGCCAGTTGCTGCTGATGAAAACTATCTCATTCATGTTTCTGCAGAGGATCAAACGAC
ACCTGTTCCTGATGCCCGACGTTCCGGCAGGTCAATTGGTGTGCCAGGAATCGTGGCAGCCCTTGGACAGCTGCATGATT
CATTCGGAAAGACCTCCTGGCAGGACGTGCTGACAACTCCGCAGCAGCTCGCAACTGATGGGTTTTCCATCAGCCCTCGC
ATGTCAGCATCAATTGCTAACTCCGCTGAGGATCTCTCCCACGATCCGGAAGCTGCCGCATATTTCCTTGATGAAAACGG
TGATGCGAAGGCACCCGGCACACTTTTACAAAACCCTGACTATGCAGAAACGATTCGTCTCATCTCTGAAGGTGGCCCCG
ATGCGTTCTACACGGGTGAGATTGCAGCAGACATCGTGGAACGCGCCACCCGTGAGGTTGACGGTTTCACACCATCACTG
ATGAGCACGGCAGATTTGGCTGCCTACACTCCGGAAACTCGTGAAGCTTTGTGTGCTCCCTACCGCGACAAGATTGTTTG
TGGCATGCCACCGTCATCATCGGGTGGCGTCACAGTGATGGAAACCCTGGGTATCTTGAACAACTTTGATCTCGCCCAAT
ACCCACCCACTGAGGTTGGTTTGGATGGCGGATTGCCAAATGCGGAAGCTGTTCACCTGATTTCAGAGGCCGAGCGCCTG
GCTTATGCTGATCGCGATGCTTACATCGGTGATCCTGCTTTCGTGGAAGTTCCAGCAGGTGGTGTCGAAGAGTTGATCAG
CGATGTCTACACGGGTAAACGCTCAGAACTTATTGATCCAGAGCATTCAATGGGTCAGGCAACTGCTGGTCTGAGCCAGG
AACCAGTCATGGCTGCCCTGCCGGAAAGTGGCACCAGCCATATTTCCATCATCGATTCCTATGGCAACGCAGCATCGTTG
ACCACCAGTGTGGAAGCTGCTTTCGGTTCCTTCCACTTCACCCGTGGTTTCATTTTGAATAATCAGCTGACAGATTTCTC
CGCTGAACCACTTGATGAGGACGGCGAGCCCGTGGCCAATCGTGTCGAGTCAGCAAAGCGCCCACGGTCTTCCATGTCGC
CAATGCTAGTGTTCAACGCCAGTGGCGATGGTGAAATCGCGGATCTGAATATGGTGCTGGGCTCCCCTGGCGGATCCTTG
ATTATTCAGTACGTGGTGAAAACCCTGGTCAACATCATCGACTGGGATATGGATCCACAGCAGGCAGTGTCTGCGCCCAA
CTTTGGTGCGATGAACCAGCCTAAGACTGGACTGGGAAGCGAGCATCCGCTGATCGCCAATGATTCAGCAGAGCTTGTAA
CTGAACTGGAAAGCAAAGGCCACGAAGTTAACGTGGGCGAGCAATCCAGTGGCCTATCGGCGTTGGTGAAAAACGGTGAC
ACCATTGTCGGTGGCGCCGATCCACGTAGAGAAGGCGTGGTCTTGGGTGGCTAA

Upstream 100 bases:

>100_bases
ACGGCGAAACAAATGCAAGTCCCCAATCATGGGTTCTTACCAATTAAATTTTCTTTCGGAAAATATCTCCCCCATAAGAT
TTCCTTGATAGGCTCGAGAA

Downstream 100 bases:

>100_bases
TTAGCGCGCAGACCACGCTGACCACAGCGCTTCATAACGACCGCCGATTGCTCGGAGTTGTTCATGTGTTCCGGATTCTA
TGATTTCTCCGGAATCCATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 657; Mature: 657

Protein sequence:

>657_residues
MKVTQSTFLKSVAVFTVAALTLTISSCSSGEDTSASSTDAENSSTQAAASPPLAPCELPADASAEEEVEGTHTGEDISVA
PEIGTGYREGMTPVQTQGYAVATANPIASEAACAVLREGGTAADALVTAQFVLGLTEPQSSGLGGGGYILYYDAEANAVT
AIDGRETAPVAADENYLIHVSAEDQTTPVPDARRSGRSIGVPGIVAALGQLHDSFGKTSWQDVLTTPQQLATDGFSISPR
MSASIANSAEDLSHDPEAAAYFLDENGDAKAPGTLLQNPDYAETIRLISEGGPDAFYTGEIAADIVERATREVDGFTPSL
MSTADLAAYTPETREALCAPYRDKIVCGMPPSSSGGVTVMETLGILNNFDLAQYPPTEVGLDGGLPNAEAVHLISEAERL
AYADRDAYIGDPAFVEVPAGGVEELISDVYTGKRSELIDPEHSMGQATAGLSQEPVMAALPESGTSHISIIDSYGNAASL
TTSVEAAFGSFHFTRGFILNNQLTDFSAEPLDEDGEPVANRVESAKRPRSSMSPMLVFNASGDGEIADLNMVLGSPGGSL
IIQYVVKTLVNIIDWDMDPQQAVSAPNFGAMNQPKTGLGSEHPLIANDSAELVTELESKGHEVNVGEQSSGLSALVKNGD
TIVGGADPRREGVVLGG

Sequences:

>Translated_657_residues
MKVTQSTFLKSVAVFTVAALTLTISSCSSGEDTSASSTDAENSSTQAAASPPLAPCELPADASAEEEVEGTHTGEDISVA
PEIGTGYREGMTPVQTQGYAVATANPIASEAACAVLREGGTAADALVTAQFVLGLTEPQSSGLGGGGYILYYDAEANAVT
AIDGRETAPVAADENYLIHVSAEDQTTPVPDARRSGRSIGVPGIVAALGQLHDSFGKTSWQDVLTTPQQLATDGFSISPR
MSASIANSAEDLSHDPEAAAYFLDENGDAKAPGTLLQNPDYAETIRLISEGGPDAFYTGEIAADIVERATREVDGFTPSL
MSTADLAAYTPETREALCAPYRDKIVCGMPPSSSGGVTVMETLGILNNFDLAQYPPTEVGLDGGLPNAEAVHLISEAERL
AYADRDAYIGDPAFVEVPAGGVEELISDVYTGKRSELIDPEHSMGQATAGLSQEPVMAALPESGTSHISIIDSYGNAASL
TTSVEAAFGSFHFTRGFILNNQLTDFSAEPLDEDGEPVANRVESAKRPRSSMSPMLVFNASGDGEIADLNMVLGSPGGSL
IIQYVVKTLVNIIDWDMDPQQAVSAPNFGAMNQPKTGLGSEHPLIANDSAELVTELESKGHEVNVGEQSSGLSALVKNGD
TIVGGADPRREGVVLGG
>Mature_657_residues
MKVTQSTFLKSVAVFTVAALTLTISSCSSGEDTSASSTDAENSSTQAAASPPLAPCELPADASAEEEVEGTHTGEDISVA
PEIGTGYREGMTPVQTQGYAVATANPIASEAACAVLREGGTAADALVTAQFVLGLTEPQSSGLGGGGYILYYDAEANAVT
AIDGRETAPVAADENYLIHVSAEDQTTPVPDARRSGRSIGVPGIVAALGQLHDSFGKTSWQDVLTTPQQLATDGFSISPR
MSASIANSAEDLSHDPEAAAYFLDENGDAKAPGTLLQNPDYAETIRLISEGGPDAFYTGEIAADIVERATREVDGFTPSL
MSTADLAAYTPETREALCAPYRDKIVCGMPPSSSGGVTVMETLGILNNFDLAQYPPTEVGLDGGLPNAEAVHLISEAERL
AYADRDAYIGDPAFVEVPAGGVEELISDVYTGKRSELIDPEHSMGQATAGLSQEPVMAALPESGTSHISIIDSYGNAASL
TTSVEAAFGSFHFTRGFILNNQLTDFSAEPLDEDGEPVANRVESAKRPRSSMSPMLVFNASGDGEIADLNMVLGSPGGSL
IIQYVVKTLVNIIDWDMDPQQAVSAPNFGAMNQPKTGLGSEHPLIANDSAELVTELESKGHEVNVGEQSSGLSALVKNGD
TIVGGADPRREGVVLGG

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=548, Percent_Identity=25.1824817518248, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI73915090, Length=548, Percent_Identity=25.1824817518248, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI73915096, Length=548, Percent_Identity=25.1824817518248, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI73915094, Length=548, Percent_Identity=25.1824817518248, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI113429324, Length=554, Percent_Identity=25.4512635379061, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI109148539, Length=572, Percent_Identity=26.3986013986014, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI113429326, Length=553, Percent_Identity=25.3164556962025, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI153266885, Length=497, Percent_Identity=25.5533199195171, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI153266901, Length=498, Percent_Identity=25.3012048192771, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI153266907, Length=497, Percent_Identity=23.943661971831, Blast_Score=105, Evalue=1e-22,
Organism=Escherichia coli, GI1789856, Length=573, Percent_Identity=34.0314136125654, Blast_Score=257, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI72000294, Length=526, Percent_Identity=30.6083650190114, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI212646519, Length=526, Percent_Identity=30.6083650190114, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193208247, Length=569, Percent_Identity=30.0527240773286, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI193208245, Length=569, Percent_Identity=30.0527240773286, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17542894, Length=568, Percent_Identity=30.1056338028169, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17506189, Length=512, Percent_Identity=27.9296875, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17564448, Length=463, Percent_Identity=26.5658747300216, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI72001497, Length=237, Percent_Identity=25.3164556962025, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72001495, Length=237, Percent_Identity=25.3164556962025, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6323330, Length=494, Percent_Identity=24.8987854251012, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45551474, Length=571, Percent_Identity=27.84588441331, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24642670, Length=571, Percent_Identity=27.84588441331, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24642666, Length=571, Percent_Identity=27.84588441331, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI161077880, Length=571, Percent_Identity=27.84588441331, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI161077878, Length=571, Percent_Identity=27.84588441331, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI18859741, Length=572, Percent_Identity=27.0979020979021, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859893, Length=491, Percent_Identity=24.847250509165, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI161077496, Length=552, Percent_Identity=25, Blast_Score=118, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 68190; Mature: 68190

Theoretical pI: Translated: 3.92; Mature: 3.92

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTQSTFLKSVAVFTVAALTLTISSCSSGEDTSASSTDAENSSTQAAASPPLAPCELPA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DASAEEEVEGTHTGEDISVAPEIGTGYREGMTPVQTQGYAVATANPIASEAACAVLREGG
CCCCHHHCCCCCCCCCEEECCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
TAADALVTAQFVLGLTEPQSSGLGGGGYILYYDAEANAVTAIDGRETAPVAADENYLIHV
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEE
SAEDQTTPVPDARRSGRSIGVPGIVAALGQLHDSFGKTSWQDVLTTPQQLATDGFSISPR
ECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCCCC
MSASIANSAEDLSHDPEAAAYFLDENGDAKAPGTLLQNPDYAETIRLISEGGPDAFYTGE
HHHHHHCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEECHH
IAADIVERATREVDGFTPSLMSTADLAAYTPETREALCAPYRDKIVCGMPPSSSGGVTVM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCCCEEHH
ETLGILNNFDLAQYPPTEVGLDGGLPNAEAVHLISEAERLAYADRDAYIGDPAFVEVPAG
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
GVEELISDVYTGKRSELIDPEHSMGQATAGLSQEPVMAALPESGTSHISIIDSYGNAASL
CHHHHHHHHHCCCCCCCCCCCHHHCHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCH
TTSVEAAFGSFHFTRGFILNNQLTDFSAEPLDEDGEPVANRVESAKRPRSSMSPMLVFNA
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEC
SGDGEIADLNMVLGSPGGSLIIQYVVKTLVNIIDWDMDPQQAVSAPNFGAMNQPKTGLGS
CCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCC
EHPLIANDSAELVTELESKGHEVNVGEQSSGLSALVKNGDTIVGGADPRREGVVLGG
CCCEEECCHHHHHHHHHHCCCEECCCCCCCCHHHHHHCCCEEECCCCCCCCCEEECC
>Mature Secondary Structure
MKVTQSTFLKSVAVFTVAALTLTISSCSSGEDTSASSTDAENSSTQAAASPPLAPCELPA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DASAEEEVEGTHTGEDISVAPEIGTGYREGMTPVQTQGYAVATANPIASEAACAVLREGG
CCCCHHHCCCCCCCCCEEECCCCCCCHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
TAADALVTAQFVLGLTEPQSSGLGGGGYILYYDAEANAVTAIDGRETAPVAADENYLIHV
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCEEEEE
SAEDQTTPVPDARRSGRSIGVPGIVAALGQLHDSFGKTSWQDVLTTPQQLATDGFSISPR
ECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCCCCC
MSASIANSAEDLSHDPEAAAYFLDENGDAKAPGTLLQNPDYAETIRLISEGGPDAFYTGE
HHHHHHCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEECHH
IAADIVERATREVDGFTPSLMSTADLAAYTPETREALCAPYRDKIVCGMPPSSSGGVTVM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCEEECCCCCCCCCEEHH
ETLGILNNFDLAQYPPTEVGLDGGLPNAEAVHLISEAERLAYADRDAYIGDPAFVEVPAG
HHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
GVEELISDVYTGKRSELIDPEHSMGQATAGLSQEPVMAALPESGTSHISIIDSYGNAASL
CHHHHHHHHHCCCCCCCCCCCHHHCHHHCCCCCCCCEEECCCCCCCEEEEEECCCCCCCH
TTSVEAAFGSFHFTRGFILNNQLTDFSAEPLDEDGEPVANRVESAKRPRSSMSPMLVFNA
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEC
SGDGEIADLNMVLGSPGGSLIIQYVVKTLVNIIDWDMDPQQAVSAPNFGAMNQPKTGLGS
CCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCC
EHPLIANDSAELVTELESKGHEVNVGEQSSGLSALVKNGDTIVGGADPRREGVVLGG
CCCEEECCHHHHHHHHHHCCCEECCCCCCCCHHHHHHCCCEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]