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The map label for this gene is msbA [H]

Identifier: 145295111

GI number: 145295111

Start: 1161882

End: 1163282

Strand: Direct

Name: msbA [H]

Synonym: cgR_1054

Alternate gene names: 145295111

Gene position: 1161882-1163282 (Clockwise)

Preceding gene: 145295110

Following gene: 145295112

Centisome position: 35.06

GC content: 55.03

Gene sequence:

>1401_bases
ATGATCAGGCGGCAGCGGGGCAAGGTTGCGTTTGGCGCATTCTTTTTGGGGATGTGGCAGCTGTCGGAAGCGTTGGTGCC
GATTGCGATTGGTTTGATCGTTGATCATGCGGTTCTCACAAAAGATCTCCGCCGATTAGTGGTCGGGCTTGTCGCTTTTG
TTGTGCTGTTTGTGGTGTTGAGTTTTTCTTATCGTTTCGGTTCGCGCGCGTTGAATAGGGCCGTGAACTTTGAATCCCAT
GCGCTCCGCGTAGAGGTAGCCGATCATGCGTTGAAAAATCTGGATCCGCGCAATTTGGTGCCTGGCGAGGTGATGTCGCG
GTCCACCGCAGATGCGGATTCTTCGACGCGTATTTTCGGGCAGATCGGAACGGGTGTTTCGGCTGCGACGGGATTTCTTG
GTGCAGCGACCTACCTGTTGATCAGTGACTGGCTGGTCGGGTTGTTGGTGCTTGTGCTGGTACCGATCATTTCGGGAGTG
GTTGCACTGGCTAGCAAGGGCATTTCTAAAAGGAGTGTCACCCAGCAGGAGAAGTTGGCGGAGTCTGGTGCGCAGGCAAG
TGACATCATGATGGGGCTGCGCGTAATCAAGGCGATCGGTGGCGAGCGTTGGGCCGTGAAGACTTTTGAAAAGGCGTCGC
AGGCATCAGCGAGAGCGGCGGTTGATACTGCAGTTGCTTCGGGCAAAGTCGCTGGTATTGGTGAGTTGTCCATTGCGGTG
AATTTGGCTGCGGTGTTGTTGCTTGCTGGTTGGCGGGTCACCACGGGGGAGTTGGGGCCTGGCCAGTTGATCGCAATTGT
GGGTGTGGCGGTGTATTTGTCAGAGCCGATTCGCTTGCTGAGCAACTCGATTAATGCCTCAGCTATTGCGCACGGTGCAG
CTAAGCGGGTGGCTAATTTCTTAAACCTCGACGAATCTCAGGCACAGTACGAAAGCAGCGAAACAATCAATGACGGCGAA
TTCCTCGTCATCGTGCCCCCAGCCAGCACGCTTCCACACGGCGACAATATCTTGGCTACACCTCATGCTGCCGACATTTT
CGAAGGCACCTTGCGGTCAAATATTTCCATGAATCATGAGGACAACGTGCCAATTGATCCGCAGGTAATTCGCGCTTCTG
GTCTGACTGACATCATTGAGGTGGACGGACTTGATGCGCCGGTGCGCGATACGGGAAGCAATTTATCGGGTGGGCAGCGT
CAGCGAGTGGCTTTGGCCAGGGCGTTGCATGCAGACGCGGAAGTACTGGTGCTGATGGATCCAACCAGCGCGGTGGATTC
GGTGACGGAGGTGTCTATCGCGCAGGGGATTAAGCAGCTGCGAGCAGGCAAAACCACCATTGTGGTGAGTTCTTCGCCCG
CGTTTTACAACTTGGCGGATCGGGTGATTTCACATGTCTAA

Upstream 100 bases:

>100_bases
TAAGTCAGTGTTACCTAAGTTAGGCTGTTGGGAATTGAACTGACACATAGACAGGGTTTTGATGAGAACAACACACACCG
CTTCAAGCATTCTGCGAAGA

Downstream 100 bases:

>100_bases
TTTGATGGCATCATCGACACCGAAACAGGCGTTCAGCGCTGCTTTCACGCAACTGAAACCGCACCGGATCAAGTTATTTG
GGGTTGTTCTTTGTGGCGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MIRRQRGKVAFGAFFLGMWQLSEALVPIAIGLIVDHAVLTKDLRRLVVGLVAFVVLFVVLSFSYRFGSRALNRAVNFESH
ALRVEVADHALKNLDPRNLVPGEVMSRSTADADSSTRIFGQIGTGVSAATGFLGAATYLLISDWLVGLLVLVLVPIISGV
VALASKGISKRSVTQQEKLAESGAQASDIMMGLRVIKAIGGERWAVKTFEKASQASARAAVDTAVASGKVAGIGELSIAV
NLAAVLLLAGWRVTTGELGPGQLIAIVGVAVYLSEPIRLLSNSINASAIAHGAAKRVANFLNLDESQAQYESSETINDGE
FLVIVPPASTLPHGDNILATPHAADIFEGTLRSNISMNHEDNVPIDPQVIRASGLTDIIEVDGLDAPVRDTGSNLSGGQR
QRVALARALHADAEVLVLMDPTSAVDSVTEVSIAQGIKQLRAGKTTIVVSSSPAFYNLADRVISHV

Sequences:

>Translated_466_residues
MIRRQRGKVAFGAFFLGMWQLSEALVPIAIGLIVDHAVLTKDLRRLVVGLVAFVVLFVVLSFSYRFGSRALNRAVNFESH
ALRVEVADHALKNLDPRNLVPGEVMSRSTADADSSTRIFGQIGTGVSAATGFLGAATYLLISDWLVGLLVLVLVPIISGV
VALASKGISKRSVTQQEKLAESGAQASDIMMGLRVIKAIGGERWAVKTFEKASQASARAAVDTAVASGKVAGIGELSIAV
NLAAVLLLAGWRVTTGELGPGQLIAIVGVAVYLSEPIRLLSNSINASAIAHGAAKRVANFLNLDESQAQYESSETINDGE
FLVIVPPASTLPHGDNILATPHAADIFEGTLRSNISMNHEDNVPIDPQVIRASGLTDIIEVDGLDAPVRDTGSNLSGGQR
QRVALARALHADAEVLVLMDPTSAVDSVTEVSIAQGIKQLRAGKTTIVVSSSPAFYNLADRVISHV
>Mature_466_residues
MIRRQRGKVAFGAFFLGMWQLSEALVPIAIGLIVDHAVLTKDLRRLVVGLVAFVVLFVVLSFSYRFGSRALNRAVNFESH
ALRVEVADHALKNLDPRNLVPGEVMSRSTADADSSTRIFGQIGTGVSAATGFLGAATYLLISDWLVGLLVLVLVPIISGV
VALASKGISKRSVTQQEKLAESGAQASDIMMGLRVIKAIGGERWAVKTFEKASQASARAAVDTAVASGKVAGIGELSIAV
NLAAVLLLAGWRVTTGELGPGQLIAIVGVAVYLSEPIRLLSNSINASAIAHGAAKRVANFLNLDESQAQYESSETINDGE
FLVIVPPASTLPHGDNILATPHAADIFEGTLRSNISMNHEDNVPIDPQVIRASGLTDIIEVDGLDAPVRDTGSNLSGGQR
QRVALARALHADAEVLVLMDPTSAVDSVTEVSIAQGIKQLRAGKTTIVVSSSPAFYNLADRVISHV

Specific function: Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG1132

COG function: function code V; ABC-type multidrug transport system, ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955970, Length=380, Percent_Identity=24.2105263157895, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786653, Length=528, Percent_Identity=25, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787112, Length=140, Percent_Identity=30.7142857142857, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787143, Length=82, Percent_Identity=37.8048780487805, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=418, Percent_Identity=21.0526315789474, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17569143, Length=134, Percent_Identity=35.8208955223881, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=123, Percent_Identity=35.7723577235772, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=110, Percent_Identity=36.3636363636364, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533971, Length=211, Percent_Identity=22.7488151658768, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=137, Percent_Identity=30.6569343065693, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567269, Length=109, Percent_Identity=34.8623853211009, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17569145, Length=133, Percent_Identity=33.0827067669173, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320339, Length=129, Percent_Identity=34.1085271317829, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI85726357, Length=502, Percent_Identity=23.3067729083665, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR011917
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 49114; Mature: 49114

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRQRGKVAFGAFFLGMWQLSEALVPIAIGLIVDHAVLTKDLRRLVVGLVAFVVLFVVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFSYRFGSRALNRAVNFESHALRVEVADHALKNLDPRNLVPGEVMSRSTADADSSTRIFG
HHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEE
QIGTGVSAATGFLGAATYLLISDWLVGLLVLVLVPIISGVVALASKGISKRSVTQQEKLA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ESGAQASDIMMGLRVIKAIGGERWAVKTFEKASQASARAAVDTAVASGKVAGIGELSIAV
HCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NLAAVLLLAGWRVTTGELGPGQLIAIVGVAVYLSEPIRLLSNSINASAIAHGAAKRVANF
HHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LNLDESQAQYESSETINDGEFLVIVPPASTLPHGDNILATPHAADIFEGTLRSNISMNHE
HCCCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCC
DNVPIDPQVIRASGLTDIIEVDGLDAPVRDTGSNLSGGQRQRVALARALHADAEVLVLMD
CCCCCCHHHHECCCCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEC
PTSAVDSVTEVSIAQGIKQLRAGKTTIVVSSSPAFYNLADRVISHV
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIRRQRGKVAFGAFFLGMWQLSEALVPIAIGLIVDHAVLTKDLRRLVVGLVAFVVLFVVL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFSYRFGSRALNRAVNFESHALRVEVADHALKNLDPRNLVPGEVMSRSTADADSSTRIFG
HHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEE
QIGTGVSAATGFLGAATYLLISDWLVGLLVLVLVPIISGVVALASKGISKRSVTQQEKLA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ESGAQASDIMMGLRVIKAIGGERWAVKTFEKASQASARAAVDTAVASGKVAGIGELSIAV
HCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NLAAVLLLAGWRVTTGELGPGQLIAIVGVAVYLSEPIRLLSNSINASAIAHGAAKRVANF
HHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LNLDESQAQYESSETINDGEFLVIVPPASTLPHGDNILATPHAADIFEGTLRSNISMNHE
HCCCHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCC
DNVPIDPQVIRASGLTDIIEVDGLDAPVRDTGSNLSGGQRQRVALARALHADAEVLVLMD
CCCCCCHHHHECCCCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEC
PTSAVDSVTEVSIAQGIKQLRAGKTTIVVSSSPAFYNLADRVISHV
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]