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The map label for this gene is degP [H]

Identifier: 145295046

GI number: 145295046

Start: 1094876

End: 1096201

Strand: Direct

Name: degP [H]

Synonym: cgR_0990

Alternate gene names: 145295046

Gene position: 1094876-1096201 (Clockwise)

Preceding gene: 145295045

Following gene: 145295047

Centisome position: 33.04

GC content: 51.51

Gene sequence:

>1326_bases
ATGACAAATCAATTCCCCACAAACAACGGTGAGAACCCGGACCGCGCATCGGAAACTCCATCAGAAACCAACTCCTTCGA
ACATGTGCGTAGTTCATATCCGCAGTGGGGTAACACTGCTTCCAATCAAAACCCCTATCCTGGTGCGGGCTTCGGCTCTG
AACAAAACACTCAACAAGGAAATGAGCAACAAGCTCCAGCCTGGACCAGTTGGGATAATCAGCCTCTAAGCACAGATGTA
AAGCCAGCTAAAGAAAAGCGAAAAGTTGGCATCGGAACGGCACTCGCGTTAATGCTTGTTGGTTCTATTGCTACCGGTAG
CGTTGTGGGTGTTGCAGCAACCCAGCTTGGTTCGGACTCTTCAACCCCAGTTAATGCTCTCGAGCAGCCCAGCGTGCAGC
GCACCACTAATGCTGAACCAGGTTCAGCGGAACAGGTTGCTGCCGCAGTTTTGCCTTCTGTCGTCTCTATTCAGGCCATT
ACTAGGACGTCTGCTTCTGAGGGCTCTGGATCCATTATTTCCTCTGATGGTTACGTCATGACCAATAATCACGTCGTGGC
AGGCATTGAACAATCTGGTGTGTTGGAAGTAAGTTTCTCCGATGGAGCTACAGCGCAAGCTGATTTTATTGCTGGGGATC
CTTCCACAGATATTGCTGTGATCAAGATTAGGGATGTGTCCAACCTTCCAGTTATGAGCTTTGGAGATTCGGACGCATTA
GGCGTTGGACAAAGTGTGATGGCTGTTGGTTCTCCACTGGGTCTGAGCTCCACTGTGACCACCGGTATTGTGTCGGCCGT
GAACCGTCCTGTGCGAGCTTCTGGTGATGGCGGAGAGTCGTCCCTCATCGATGCTATCCAGACCGATGCTGCGATCAACC
CTGGTAACTCTGGTGGTCCGCTGGTTGATATGGATGGCAACCTCATTGGCATGAATTCGGTAATTGCATCGATTTCGAGC
ACCAGCGATTCCGCAGGTTCCATTGGTCTTGGTTTTGCTATCCCATCCAACTTTGCCAAGCGCGTGGCCGATCAATTGAT
CAGCACCGGCCAGGTAACTCAGCCGATGATCGGTGTGCAGGTTGGCACTGACAACTCAGTGACAGGCGCTGTGATCGCCA
GTGTTCAAGATGGTGGACCGGCCGCAGATGCTGGACTTCAGCCAGGTGATATCGTGACCAAGCTCAATGATCGAGTTATT
GATAGCCCAGACTCCTTGATCGCTGCTGTTCGTTCGCATGATTTTGGCGAAACCGTCACTTTAACAATTACACAGCCAGA
TACCTCGCAGAGCCGGGAGGTAGAGGTTACTCTGACGAGTGAGTAG

Upstream 100 bases:

>100_bases
GCGGGTTCGAAAATGTCGATGATTAAACCACTAAAGAGCTCACAGGAAGTGTTCAGACTACTTAGAGTGACGCCCCAGCC
ACAGGGTTCATAATCAAATC

Downstream 100 bases:

>100_bases
GTTTAAAAGAGTTAATCTGCATCTAATCAAGTAGCCAAGTATGAGTGAGGAACAATGAGCAAGGATCCATTGGGAAGTCT
TACCGATGTTGTAGACACAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTNQFPTNNGENPDRASETPSETNSFEHVRSSYPQWGNTASNQNPYPGAGFGSEQNTQQGNEQQAPAWTSWDNQPLSTDV
KPAKEKRKVGIGTALALMLVGSIATGSVVGVAATQLGSDSSTPVNALEQPSVQRTTNAEPGSAEQVAAAVLPSVVSIQAI
TRTSASEGSGSIISSDGYVMTNNHVVAGIEQSGVLEVSFSDGATAQADFIAGDPSTDIAVIKIRDVSNLPVMSFGDSDAL
GVGQSVMAVGSPLGLSSTVTTGIVSAVNRPVRASGDGGESSLIDAIQTDAAINPGNSGGPLVDMDGNLIGMNSVIASISS
TSDSAGSIGLGFAIPSNFAKRVADQLISTGQVTQPMIGVQVGTDNSVTGAVIASVQDGGPAADAGLQPGDIVTKLNDRVI
DSPDSLIAAVRSHDFGETVTLTITQPDTSQSREVEVTLTSE

Sequences:

>Translated_441_residues
MTNQFPTNNGENPDRASETPSETNSFEHVRSSYPQWGNTASNQNPYPGAGFGSEQNTQQGNEQQAPAWTSWDNQPLSTDV
KPAKEKRKVGIGTALALMLVGSIATGSVVGVAATQLGSDSSTPVNALEQPSVQRTTNAEPGSAEQVAAAVLPSVVSIQAI
TRTSASEGSGSIISSDGYVMTNNHVVAGIEQSGVLEVSFSDGATAQADFIAGDPSTDIAVIKIRDVSNLPVMSFGDSDAL
GVGQSVMAVGSPLGLSSTVTTGIVSAVNRPVRASGDGGESSLIDAIQTDAAINPGNSGGPLVDMDGNLIGMNSVIASISS
TSDSAGSIGLGFAIPSNFAKRVADQLISTGQVTQPMIGVQVGTDNSVTGAVIASVQDGGPAADAGLQPGDIVTKLNDRVI
DSPDSLIAAVRSHDFGETVTLTITQPDTSQSREVEVTLTSE
>Mature_440_residues
TNQFPTNNGENPDRASETPSETNSFEHVRSSYPQWGNTASNQNPYPGAGFGSEQNTQQGNEQQAPAWTSWDNQPLSTDVK
PAKEKRKVGIGTALALMLVGSIATGSVVGVAATQLGSDSSTPVNALEQPSVQRTTNAEPGSAEQVAAAVLPSVVSIQAIT
RTSASEGSGSIISSDGYVMTNNHVVAGIEQSGVLEVSFSDGATAQADFIAGDPSTDIAVIKIRDVSNLPVMSFGDSDALG
VGQSVMAVGSPLGLSSTVTTGIVSAVNRPVRASGDGGESSLIDAIQTDAAINPGNSGGPLVDMDGNLIGMNSVIASISST
SDSAGSIGLGFAIPSNFAKRVADQLISTGQVTQPMIGVQVGTDNSVTGAVIASVQDGGPAADAGLQPGDIVTKLNDRVID
SPDSLIAAVRSHDFGETVTLTITQPDTSQSREVEVTLTSE

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=279, Percent_Identity=34.7670250896057, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI22129776, Length=291, Percent_Identity=35.0515463917526, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7019477, Length=310, Percent_Identity=33.5483870967742, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI24308541, Length=309, Percent_Identity=32.0388349514563, Blast_Score=122, Evalue=6e-28,
Organism=Escherichia coli, GI1786356, Length=286, Percent_Identity=40.2097902097902, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789629, Length=283, Percent_Identity=40.2826855123675, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789630, Length=322, Percent_Identity=31.9875776397516, Blast_Score=136, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646839, Length=304, Percent_Identity=34.8684210526316, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 44831; Mature: 44699

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQFPTNNGENPDRASETPSETNSFEHVRSSYPQWGNTASNQNPYPGAGFGSEQNTQQG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NEQQAPAWTSWDNQPLSTDVKPAKEKRKVGIGTALALMLVGSIATGSVVGVAATQLGSDS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCCC
STPVNALEQPSVQRTTNAEPGSAEQVAAAVLPSVVSIQAITRTSASEGSGSIISSDGYVM
CCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEE
TNNHVVAGIEQSGVLEVSFSDGATAQADFIAGDPSTDIAVIKIRDVSNLPVMSFGDSDAL
ECCEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCEEECCCCCCC
GVGQSVMAVGSPLGLSSTVTTGIVSAVNRPVRASGDGGESSLIDAIQTDAAINPGNSGGP
CCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
LVDMDGNLIGMNSVIASISSTSDSAGSIGLGFAIPSNFAKRVADQLISTGQVTQPMIGVQ
EEECCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEE
VGTDNSVTGAVIASVQDGGPAADAGLQPGDIVTKLNDRVIDSPDSLIAAVRSHDFGETVT
ECCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEE
LTITQPDTSQSREVEVTLTSE
EEEECCCCCCCCEEEEEEECC
>Mature Secondary Structure 
TNQFPTNNGENPDRASETPSETNSFEHVRSSYPQWGNTASNQNPYPGAGFGSEQNTQQG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NEQQAPAWTSWDNQPLSTDVKPAKEKRKVGIGTALALMLVGSIATGSVVGVAATQLGSDS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCCC
STPVNALEQPSVQRTTNAEPGSAEQVAAAVLPSVVSIQAITRTSASEGSGSIISSDGYVM
CCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEE
TNNHVVAGIEQSGVLEVSFSDGATAQADFIAGDPSTDIAVIKIRDVSNLPVMSFGDSDAL
ECCEEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCEEEEEEECCCCCCEEECCCCCCC
GVGQSVMAVGSPLGLSSTVTTGIVSAVNRPVRASGDGGESSLIDAIQTDAAINPGNSGGP
CCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
LVDMDGNLIGMNSVIASISSTSDSAGSIGLGFAIPSNFAKRVADQLISTGQVTQPMIGVQ
EEECCCCEEEHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEE
VGTDNSVTGAVIASVQDGGPAADAGLQPGDIVTKLNDRVIDSPDSLIAAVRSHDFGETVT
ECCCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEE
LTITQPDTSQSREVEVTLTSE
EEEECCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]