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The map label for this gene is nei [C]

Identifier: 145295018

GI number: 145295018

Start: 1069166

End: 1069936

Strand: Direct

Name: nei [C]

Synonym: cgR_0962

Alternate gene names: 145295018

Gene position: 1069166-1069936 (Clockwise)

Preceding gene: 145295017

Following gene: 145295019

Centisome position: 32.26

GC content: 55.25

Gene sequence:

>771_bases
ATGCCAGAAGGTGATTCCGTATTCCAACTCTCCCGCAAACTTCAATTCATGCGCGGAAGAGAAGTGCTGGAAACCTCCCT
GCGTGTGCCATCAGTGGCACTTCACGATTTCACCGGTCAAACCGTCAACCGCGTATGGCCCTACGGAAAACACCTCTTCA
TGCAATTCGGTGAAGAGATCCTTCACACCCACCTCAAAATGGAAGGGACGTGGGCTGTCCACCGCAAAGGCGATCGCTGG
CGCAAACCTGGACACACCGCGAGGGTAGTGCTTGTGCTGTCGGAAAACATTGAGGTGGTGGGGCATTCCCTCGGCTTTGT
CAGAGTGTTCCCCGCAAACCGCTACTCCGAAGAGATCGCTTACCTCGGACCCGACGTCCTTGCCGAAGAATTCGACATCA
ACACAGCACGGAACAATATTGCATCGAACCCTTCCCGAACAATTGGCGAAGCCCTCCTCGACCAATCCAACCTCGCTGGA
GTAGGCAACGAATACCGCGCTGAGATCTGCTTCCTCATGGGCGTCCACCCGGCGACACAAGTGGGATACGTTGACGTCGA
AAAGGCTCTGAAGATTACCCGAAGACTCATGTGGGAAAATCGAAATTCGCCGATTCGAGTGACCACTGGGGTTCGACGCG
CCGGGGAATCCACCTACGTGTTCGGGCGTAACAAAAAACCGTGCAGGAGATGCCGAACCCCAATCGTGAAAGCCGAGTTG
GGGGAGCGAATAATCTGGTGGTGTCCGCGCTGCCAACCGCTAAACTCGTGA

Upstream 100 bases:

>100_bases
GGGAATGCGATTTCGACCACCAGTGGCACGGGAAACCCCCGCAGATACGCTTCCCACCAGGCCTTTTCGTGGAGGCTTCG
GACGGCGCTAACCTGATGAC

Downstream 100 bases:

>100_bases
AGCATGAGACTAATACTCAACCTGATTTGGTTATTCTTCGGTGGCATTTGGCTCGCGTTGGGATACGTATTCTTCGGAAT
CATCGCATGTATCTTCATCG

Product: hypothetical protein

Products: NA

Alternate protein names: Putative DNA-(apurinic or apyrimidinic site) lyase SCO5760; Putative AP lyase SCO5760 [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPEGDSVFQLSRKLQFMRGREVLETSLRVPSVALHDFTGQTVNRVWPYGKHLFMQFGEEILHTHLKMEGTWAVHRKGDRW
RKPGHTARVVLVLSENIEVVGHSLGFVRVFPANRYSEEIAYLGPDVLAEEFDINTARNNIASNPSRTIGEALLDQSNLAG
VGNEYRAEICFLMGVHPATQVGYVDVEKALKITRRLMWENRNSPIRVTTGVRRAGESTYVFGRNKKPCRRCRTPIVKAEL
GERIIWWCPRCQPLNS

Sequences:

>Translated_256_residues
MPEGDSVFQLSRKLQFMRGREVLETSLRVPSVALHDFTGQTVNRVWPYGKHLFMQFGEEILHTHLKMEGTWAVHRKGDRW
RKPGHTARVVLVLSENIEVVGHSLGFVRVFPANRYSEEIAYLGPDVLAEEFDINTARNNIASNPSRTIGEALLDQSNLAG
VGNEYRAEICFLMGVHPATQVGYVDVEKALKITRRLMWENRNSPIRVTTGVRRAGESTYVFGRNKKPCRRCRTPIVKAEL
GERIIWWCPRCQPLNS
>Mature_255_residues
PEGDSVFQLSRKLQFMRGREVLETSLRVPSVALHDFTGQTVNRVWPYGKHLFMQFGEEILHTHLKMEGTWAVHRKGDRWR
KPGHTARVVLVLSENIEVVGHSLGFVRVFPANRYSEEIAYLGPDVLAEEFDINTARNNIASNPSRTIGEALLDQSNLAGV
GNEYRAEICFLMGVHPATQVGYVDVEKALKITRRLMWENRNSPIRVTTGVRRAGESTYVFGRNKKPCRRCRTPIVKAELG
ERIIWWCPRCQPLNS

Specific function: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA b

COG id: COG0266

COG function: function code L; Formamidopyrimidine-DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FPG-type zinc finger [H]

Homologues:

Organism=Homo sapiens, GI157388969, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015886
- InterPro:   IPR015887
- InterPro:   IPR012319
- InterPro:   IPR010979
- InterPro:   IPR000214 [H]

Pfam domain/function: PF01149 Fapy_DNA_glyco; PF06831 H2TH [H]

EC number: =4.2.99.18 [H]

Molecular weight: Translated: 29228; Mature: 29097

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS51066 ZF_FPG_2 ; PS51068 FPG_CAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGDSVFQLSRKLQFMRGREVLETSLRVPSVALHDFTGQTVNRVWPYGKHLFMQFGEEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCHHHHHHHHHHHH
LHTHLKMEGTWAVHRKGDRWRKPGHTARVVLVLSENIEVVGHSLGFVRVFPANRYSEEIA
HHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCEEEECCCCEEEEECCCCCHHHHH
YLGPDVLAEEFDINTARNNIASNPSRTIGEALLDQSNLAGVGNEYRAEICFLMGVHPATQ
HCCHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHEEEEEEECCCCHH
VGYVDVEKALKITRRLMWENRNSPIRVTTGVRRAGESTYVFGRNKKPCRRCRTPIVKAEL
CCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCEEEECCCCCHHHHHCCCCHHHHH
GERIIWWCPRCQPLNS
CCEEEEECCCCCCCCC
>Mature Secondary Structure 
PEGDSVFQLSRKLQFMRGREVLETSLRVPSVALHDFTGQTVNRVWPYGKHLFMQFGEEI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCHHHHHHHHHHHH
LHTHLKMEGTWAVHRKGDRWRKPGHTARVVLVLSENIEVVGHSLGFVRVFPANRYSEEIA
HHHHHCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCEEEECCCCEEEEECCCCCHHHHH
YLGPDVLAEEFDINTARNNIASNPSRTIGEALLDQSNLAGVGNEYRAEICFLMGVHPATQ
HCCHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHEEEEEEECCCCHH
VGYVDVEKALKITRRLMWENRNSPIRVTTGVRRAGESTYVFGRNKKPCRRCRTPIVKAEL
CCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCEEEECCCCCHHHHHCCCCHHHHH
GERIIWWCPRCQPLNS
CCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]