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The map label for this gene is aroA

Identifier: 145294927

GI number: 145294927

Start: 961438

End: 962730

Strand: Reverse

Name: aroA

Synonym: cgR_0873

Alternate gene names: 145294927

Gene position: 962730-961438 (Counterclockwise)

Preceding gene: 145294929

Following gene: 145294926

Centisome position: 29.05

GC content: 53.05

Gene sequence:

>1293_bases
ATGGTCTTTGTGTCTGATTCGTCTATCTCTTTGCCCATTTGGGATGCTCCGCGCGCTCGCGGCCCCATAGTCTCGGACCT
GGCTATCCCTGGTTCCAAGTCGATCACCAACCGCGCCCTCATCTTGGCTGCGCTCGCATCAACTCCATCCACCATCATTG
ATGTCCTTCGTAGTCGTGATACCGATCTCATGACTGATGGTCTACGCAGCCTCGGAATCACCATTACTGAAGAGGCAGTC
GATCGCTACCGCGTTGAGCCCGGACAGTTGTCTGCTGGCTCCGTTGAGTGTGGTCTTGCTGGTACGGTCATGCGCTTTTT
GCCTCCTGTTGCTGCTTTCGCTGATGGTCCTGTTCATTTTGATGGCGATCCTCAAGCTCGTGTTCGTCCGATGACCAGCA
TTTTGGATGCGCTGCGTTCGCTTGGTGTGGAGGTGGACAACAACAATCTGCCTTTCACTGTTAATGCTGGTGAGGTCCCT
GAGGGTGGCGTGGTTGAGATTGATGCTTCCGGCTCATCTCAGTTTGTTTCTGGTCTTTTGCTTTCAGCGCCTCGTTTTAA
AAATGGCGTCACCGTTAAGCACGTCGGTGGTCGTCTGCCGAGCATGCCGCATATTGAGATGACCGTCGATATGCTTCGTT
CCGCAGGCATTGAGATCGAAGAGTCAGAAAATCAGTGGGTTGTTCATCCTGGTGAGATCTTGGGTCGGACCTGGCGCATT
GAGCCGGATCTTTCTAATGCGACTCCGTTCCTAGCTGCCGCTGCGGTCACTGGTGGAACCATCAAGATTAATCACTGGCC
AATCAAAACTACTCAGCCTGGCGATGCTATTCGTTCGATTCTTGAGCGCATGGGCTGCGAAGTTGAGCTGGTTGCTCAGG
GTGAAGGTTACGATCTGTCGGTGACTGGTCCGGTTGCTCTCAAGGGCATTGAGATCGATATGTCCGATATCGGTGAGTTG
ACCCCTACCGTGGCGGCGTTGGCTGCGTTGGCGTCGACAGAGTCTCGTTTGACCGGTATTGCTCATCTTCGTGGCCATGA
GACGGATCGTTTGGCTGCGTTGACTGCGGAGATCAACAAACTTGGTGGAAAGTGCACTGAGCTTAAGGATGGTCTGTTGA
TTGAGCCTGCGTCGCTGCACGGTGGTGTGTGGCATTCATATGCTGATCATCGTATGGCTACTGCTGGTGCGATCATTGGC
CTCGCGGTTGATGACGTTCAGGTTGAAGACATTAAGACCACTTCCAAGACTTTCCCTGGTTTTGAAAATGTTTGGGAGGA
GATGGTTGGCTAG

Upstream 100 bases:

>100_bases
TTGCGGAGCCACGACTGATCCGTCAAGTGCTATCTCGGTTGCGTCAATAAGCGAATCACCGGTGGTGAACAAAACAAATC
TTCCACACATAACATCTATT

Downstream 100 bases:

>100_bases
ACGCAGCTATGACGAATCCGATGTTCGTGTTCGCCCAGGTAAAGGTACCCGCCCTCGTACGAAGGATCGGCCATCGCATG
AGAATGCTCTAGTGGGCATG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRDTDLMTDGLRSLGITITEEAV
DRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHFDGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVP
EGGVVEIDASGSSQFVSGLLLSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLSVTGPVALKGIEIDMSDIGEL
TPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINKLGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIG
LAVDDVQVEDIKTTSKTFPGFENVWEEMVG

Sequences:

>Translated_430_residues
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRDTDLMTDGLRSLGITITEEAV
DRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHFDGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVP
EGGVVEIDASGSSQFVSGLLLSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLSVTGPVALKGIEIDMSDIGEL
TPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINKLGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIG
LAVDDVQVEDIKTTSKTFPGFENVWEEMVG
>Mature_430_residues
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRDTDLMTDGLRSLGITITEEAV
DRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHFDGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVP
EGGVVEIDASGSSQFVSGLLLSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLSVTGPVALKGIEIDMSDIGEL
TPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINKLGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIG
LAVDDVQVEDIKTTSKTFPGFENVWEEMVG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=410, Percent_Identity=35.1219512195122, Blast_Score=182, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6320332, Length=480, Percent_Identity=31.25, Blast_Score=165, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_CORGB (A4QC99)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137748.1
- ProteinModelPortal:   A4QC99
- SMR:   A4QC99
- STRING:   A4QC99
- GeneID:   4992659
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0873
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   HRMATAG
- ProtClustDB:   PRK02427
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45586; Mature: 45586

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRD
CEEECCCCEEEEECCCCCCCCCCEEHEECCCCCCHHHHHEEEEEHHCCHHHHHHHHHCCC
TDLMTDGLRSLGITITEEAVDRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHF
CHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEE
DGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVPEGGVVEIDASGSSQFVSGLL
CCCCCHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHH
LSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
HCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCEEEE
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLS
CCCCCCCCCHHEEHEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEE
VTGPVALKGIEIDMSDIGELTPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINK
EECCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIGLAVDDVQVEDIKTTSKTFPG
HCCCHHHCCCCEEEECHHCCCCHHHHHHHHHHHHHCEEEEEEECCEEEEEECCCCCCCCC
FENVWEEMVG
HHHHHHHHCC
>Mature Secondary Structure
MVFVSDSSISLPIWDAPRARGPIVSDLAIPGSKSITNRALILAALASTPSTIIDVLRSRD
CEEECCCCEEEEECCCCCCCCCCEEHEECCCCCCHHHHHEEEEEHHCCHHHHHHHHHCCC
TDLMTDGLRSLGITITEEAVDRYRVEPGQLSAGSVECGLAGTVMRFLPPVAAFADGPVHF
CHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEE
DGDPQARVRPMTSILDALRSLGVEVDNNNLPFTVNAGEVPEGGVVEIDASGSSQFVSGLL
CCCCCHHHHHHHHHHHHHHHCCCEECCCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHH
LSAPRFKNGVTVKHVGGRLPSMPHIEMTVDMLRSAGIEIEESENQWVVHPGEILGRTWRI
HCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEECHHHCCCEEEE
EPDLSNATPFLAAAAVTGGTIKINHWPIKTTQPGDAIRSILERMGCEVELVAQGEGYDLS
CCCCCCCCCHHEEHEECCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEE
VTGPVALKGIEIDMSDIGELTPTVAALAALASTESRLTGIAHLRGHETDRLAALTAEINK
EECCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LGGKCTELKDGLLIEPASLHGGVWHSYADHRMATAGAIIGLAVDDVQVEDIKTTSKTFPG
HCCCHHHCCCCEEEECHHCCCCHHHHHHHHHHHHHCEEEEEEECCEEEEEECCCCCCCCC
FENVWEEMVG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA