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The map label for this gene is yfhA [H]

Identifier: 145294840

GI number: 145294840

Start: 870413

End: 871474

Strand: Reverse

Name: yfhA [H]

Synonym: cgR_0787

Alternate gene names: 145294840

Gene position: 871474-870413 (Counterclockwise)

Preceding gene: 145294841

Following gene: 145294839

Centisome position: 26.3

GC content: 56.5

Gene sequence:

>1062_bases
TTGGATTATTCGTCGTCAGAAAGTCAAAGAGCTATGAGCCTTAGCCATCAACTCAAGCGCCAGCGCGCATCGCGCAACTC
CCGCAGGTGGCTGATTGTTGCGGCATTGGGCGTCGTCACGCTTGGTGTTTTTACTTTTTCTTTGATGTGGGGCGAGGTGT
TTTATGGTCCTGCTCAGGTGCTGAAAGTGTTGTCTGGGCAGCAGGTTCCCGGTGCGAGTTATTCCGTTGGCGTGTTGCGT
TTGCCGCGTGCGGTGATGGGTTTGACTGCGGGTTTGGCGTTTGGCGCGGCGGGCGTGATTTTTCAGACGTTGTTGCGTAA
TCAGTTGGCGTCGCCGGATATTATCGGCATTTCTTCTGGCGCGTCGGCGGCGGGCGTGATTTGCATTGTGTTTTTCGGGA
TGTCGCAGTCTGCGGTATCGGCGATTTCTTTGTGTGCGTCCTTGGCTGTGGCGTTGTTGATTTATCTGGTGGCGTATCGC
GGTGGTTTTTCGGCCACGCGTCTGATTCTTACCGGCATTGGTATTGCTGCGATGCTGAATTCATTAGTGTCGTATTCGCT
GTCCAAGGCTGATTCTTGGGATCTGCCGACCGCGACGCGCTGGCTTACCGGCTCGCTCAATGGTGCGACGTGGGATCGTG
CGATGCCGCTGATTGTCACCACTGTGGTACTCATTCCGCTGCTGGTGGCTAATGCGCGCAATGTGGATCTTATGCGTTTG
GGCAATGATTCCGCGGTGGGTTTGGGTGTTGCTACTAATCGCACGCGCGTCATTGCGATTATTGCCGCTGTTGCGCTCAT
CGCCGTTGCTACCGCTGCATGCGGCCCGATCGCATTCGTGGCGTTTGTGTCTGGCCCCATTGCCGCGCGCATTTTAGGCT
CCGGCGGATCGCTCATCATCCCCTCCGCATTCATCGGCGGGTTGATCGTGCTCATCGCCGACCTGATTGGCCAATACTTC
CTCGGCACCCGCTACCCCGTCGGAGTTGTCACCGGCGCATTCGGCGCCCCATTCCTTATCTATTTACTCATTCGTTCCAA
CCGCGCGGGAGTAACCCTGTGA

Upstream 100 bases:

>100_bases
TGTTGATTGTTGCGGCGGATACTTTTGGGCGCGTGGTGACTCGTCCGAGTGAAATTGCCGTGGGCATCATCATGCCGCTC
ATTGGTGCGCCACTGTTTAT

Downstream 100 bases:

>100_bases
CCACCAACCATCAACTATCCGCCGAAGAAATTTCCCTGGCGTACGGCGAGCGCACCATCATTGATTCGCTCAGCGTCGAC
ATCGTCCCCGGCAAAATCAC

Product: hypothetical protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MDYSSSESQRAMSLSHQLKRQRASRNSRRWLIVAALGVVTLGVFTFSLMWGEVFYGPAQVLKVLSGQQVPGASYSVGVLR
LPRAVMGLTAGLAFGAAGVIFQTLLRNQLASPDIIGISSGASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYR
GGFSATRLILTGIGIAAMLNSLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRL
GNDSAVGLGVATNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSAFIGGLIVLIADLIGQYF
LGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL

Sequences:

>Translated_353_residues
MDYSSSESQRAMSLSHQLKRQRASRNSRRWLIVAALGVVTLGVFTFSLMWGEVFYGPAQVLKVLSGQQVPGASYSVGVLR
LPRAVMGLTAGLAFGAAGVIFQTLLRNQLASPDIIGISSGASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYR
GGFSATRLILTGIGIAAMLNSLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRL
GNDSAVGLGVATNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSAFIGGLIVLIADLIGQYF
LGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL
>Mature_353_residues
MDYSSSESQRAMSLSHQLKRQRASRNSRRWLIVAALGVVTLGVFTFSLMWGEVFYGPAQVLKVLSGQQVPGASYSVGVLR
LPRAVMGLTAGLAFGAAGVIFQTLLRNQLASPDIIGISSGASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYR
GGFSATRLILTGIGIAAMLNSLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRL
GNDSAVGLGVATNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSAFIGGLIVLIADLIGQYF
LGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=302, Percent_Identity=37.0860927152318, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790740, Length=276, Percent_Identity=34.4202898550725, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786347, Length=296, Percent_Identity=32.7702702702703, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786805, Length=315, Percent_Identity=34.2857142857143, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=29.8245614035088, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790741, Length=275, Percent_Identity=27.6363636363636, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36623; Mature: 36623

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYSSSESQRAMSLSHQLKRQRASRNSRRWLIVAALGVVTLGVFTFSLMWGEVFYGPAQV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LKVLSGQQVPGASYSVGVLRLPRAVMGLTAGLAFGAAGVIFQTLLRNQLASPDIIGISSG
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
ASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILTGIGIAAMLN
CCHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRL
HHHHHHHCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GNDSAVGLGVATNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLII
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEE
PSAFIGGLIVLIADLIGQYFLGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDYSSSESQRAMSLSHQLKRQRASRNSRRWLIVAALGVVTLGVFTFSLMWGEVFYGPAQV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LKVLSGQQVPGASYSVGVLRLPRAVMGLTAGLAFGAAGVIFQTLLRNQLASPDIIGISSG
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
ASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILTGIGIAAMLN
CCHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
SLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRL
HHHHHHHCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GNDSAVGLGVATNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLII
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEE
PSAFIGGLIVLIADLIGQYFLGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]