Click here to switch to the map view.

The map label for this gene is 145294624

Identifier: 145294624

GI number: 145294624

Start: 633103

End: 634557

Strand: Reverse

Name: 145294624

Synonym: cgR_0575

Alternate gene names: NA

Gene position: 634557-633103 (Counterclockwise)

Preceding gene: 145294630

Following gene: 145294616

Centisome position: 19.15

GC content: 56.29

Gene sequence:

>1455_bases
GTGGGAACGGGTTGGAACGGTTCGGCCGCTACTCATTCATCGCTACCTTTGGTGATCGAGTGTGGATTCATTCTTTCGGT
GAATCCAGTGAAATGGACAAAAAGCTTTTTGTTTAACCGTAGTCGACGGAAGGCACTTGAAGCACCTTGGGTTAGTCTTC
TTGCTCTCCGGACTGAGACAATGGGGTTTGTGTCTACAACTTTTGATGTGTTGATCATCGGCGCGGGCCCCTCAGGTGCC
AGCGCCGCCGTCCATGCGGCCAGGGCTGGGCTTCAAACATTGCTTATCGACGCCTCCTCCTTCCCGCGGGATAAAACGTG
TGGCGATGGCCTTACTCCCCGTGCGATTCACCAGTTAGAACTTCTAGGTGTTGCTGATCAGGTTACCGGGGATTATTTCA
ACAAGGGCTTGAAACTGCATGGTTTTGGTGGCTCTGTTGAGGCGCCGTGGCCGGAGACATATTTCACGAATAAGGGTTCC
GCGATGTCGCGGATGGAGTTCGATGATTTGTTATTCCGCTTGGCAAAATCTCATGAGGAAGTAACCACGTGGGAGAACGC
GAGCGCCCAAGACCCCATTTTGAGGGGGAATTTCTTGGAAGGCGTTGTGATTAATCACGCAGGGCAAGAGAAAACCGTCA
AGGCGAAGCATGTGATTATTGCGGATGGCGTCCGCTCCCCTTTCGGTAAGAAACTGGGTAGGCAGTGGCATCGCGATGAG
GTGTATGGCATTGCGGCTCGTGCTTATTGTGAAACTCCGCTGTCTGATGAACCGTGGATTCACTCCCATGTGGAACTGCG
CGATGAAGATGGTGTGGTGCAGCCAGGATATGGGTGGATTTTCCCGCTGGGCAACGGCACGGTGAATTTGGGTTGTGGCG
CGCTCTCGACTGATAAGAGACCAGCGAAGATCAATACGAAGAAATTGTTGAGCTTCTATGCGGGTCAGCGTCGTAAAGCA
TGGCAACTCGGGCCCGAGCACGACGTCGCCTCTGCCCTGCTGCCTATGGGCGGCGCGGTGTCAAATGTGGCTGGCGCGAA
CTGGATGCTGATCGGCGATTCCGCCGCGTGTGTGAACCCGCTGAACGGCGAAGGCATCGACTATGGCCTGGAAACCGCGG
CGATGGCCGTCGACACGCTTGTGGAAAACCCCAAGCGCGATTTGACCTTGGTATGGCCACATAGGTTGCGCGACGCGTAC
GGCGAGACCTTCATGTTGGCGCGCACGGCTGCTCGACTGCTGACGTACCCGCAGTTTTTGCCGATGGCTGGGCCGCTCGC
ATTCCGCGGGCCGCTGCAAAAGGCCATCATGCCGGCGGCTGCGCGTTTGATGGGCAACCTGATCACAGAGGAGGATAAAG
ACCTGCTCGCCAGGGGTTGGCAGGCCGCCGGATCCGCGATTAGTTGGGCGCGGAAGGGCTCCCCTCTGTGGGACTCGACT
AGTTCTCTGGTTTAA

Upstream 100 bases:

>100_bases
CTACCTGCACCATGGCGTCATTGATCCTGGCCGTTAGCTCGGGATCACCAAACTCGACCTGAGATGCTCCTGTGGTGGAT
ACACCTTCTTTTCCGAGCCC

Downstream 100 bases:

>100_bases
TCGCCGAGTGCAGCGCGACGATGCCGAAGGTCAGGTTCTGCCAACCGCAATCTGACCAACCATTCTGGTTGATCTCCCGT
GCTAGTTCCGCCTGGCTAGG

Product: hypothetical protein

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MGTGWNGSAATHSSLPLVIECGFILSVNPVKWTKSFLFNRSRRKALEAPWVSLLALRTETMGFVSTTFDVLIIGAGPSGA
SAAVHAARAGLQTLLIDASSFPRDKTCGDGLTPRAIHQLELLGVADQVTGDYFNKGLKLHGFGGSVEAPWPETYFTNKGS
AMSRMEFDDLLFRLAKSHEEVTTWENASAQDPILRGNFLEGVVINHAGQEKTVKAKHVIIADGVRSPFGKKLGRQWHRDE
VYGIAARAYCETPLSDEPWIHSHVELRDEDGVVQPGYGWIFPLGNGTVNLGCGALSTDKRPAKINTKKLLSFYAGQRRKA
WQLGPEHDVASALLPMGGAVSNVAGANWMLIGDSAACVNPLNGEGIDYGLETAAMAVDTLVENPKRDLTLVWPHRLRDAY
GETFMLARTAARLLTYPQFLPMAGPLAFRGPLQKAIMPAAARLMGNLITEEDKDLLARGWQAAGSAISWARKGSPLWDST
SSLV

Sequences:

>Translated_484_residues
MGTGWNGSAATHSSLPLVIECGFILSVNPVKWTKSFLFNRSRRKALEAPWVSLLALRTETMGFVSTTFDVLIIGAGPSGA
SAAVHAARAGLQTLLIDASSFPRDKTCGDGLTPRAIHQLELLGVADQVTGDYFNKGLKLHGFGGSVEAPWPETYFTNKGS
AMSRMEFDDLLFRLAKSHEEVTTWENASAQDPILRGNFLEGVVINHAGQEKTVKAKHVIIADGVRSPFGKKLGRQWHRDE
VYGIAARAYCETPLSDEPWIHSHVELRDEDGVVQPGYGWIFPLGNGTVNLGCGALSTDKRPAKINTKKLLSFYAGQRRKA
WQLGPEHDVASALLPMGGAVSNVAGANWMLIGDSAACVNPLNGEGIDYGLETAAMAVDTLVENPKRDLTLVWPHRLRDAY
GETFMLARTAARLLTYPQFLPMAGPLAFRGPLQKAIMPAAARLMGNLITEEDKDLLARGWQAAGSAISWARKGSPLWDST
SSLV
>Mature_483_residues
GTGWNGSAATHSSLPLVIECGFILSVNPVKWTKSFLFNRSRRKALEAPWVSLLALRTETMGFVSTTFDVLIIGAGPSGAS
AAVHAARAGLQTLLIDASSFPRDKTCGDGLTPRAIHQLELLGVADQVTGDYFNKGLKLHGFGGSVEAPWPETYFTNKGSA
MSRMEFDDLLFRLAKSHEEVTTWENASAQDPILRGNFLEGVVINHAGQEKTVKAKHVIIADGVRSPFGKKLGRQWHRDEV
YGIAARAYCETPLSDEPWIHSHVELRDEDGVVQPGYGWIFPLGNGTVNLGCGALSTDKRPAKINTKKLLSFYAGQRRKAW
QLGPEHDVASALLPMGGAVSNVAGANWMLIGDSAACVNPLNGEGIDYGLETAAMAVDTLVENPKRDLTLVWPHRLRDAYG
ETFMLARTAARLLTYPQFLPMAGPLAFRGPLQKAIMPAAARLMGNLITEEDKDLLARGWQAAGSAISWARKGSPLWDSTS
SLV

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: NA

Molecular weight: Translated: 52448; Mature: 52317

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTGWNGSAATHSSLPLVIECGFILSVNPVKWTKSFLFNRSRRKALEAPWVSLLALRTET
CCCCCCCCCCCCCCCCEEEECCEEEECCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHH
MGFVSTTFDVLIIGAGPSGASAAVHAARAGLQTLLIDASSFPRDKTCGDGLTPRAIHQLE
HHHHEEEEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LLGVADQVTGDYFNKGLKLHGFGGSVEAPWPETYFTNKGSAMSRMEFDDLLFRLAKSHEE
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCCHHHHCCHHHHHHHHHHCCHH
VTTWENASAQDPILRGNFLEGVVINHAGQEKTVKAKHVIIADGVRSPFGKKLGRQWHRDE
HHCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCHHH
VYGIAARAYCETPLSDEPWIHSHVELRDEDGVVQPGYGWIFPLGNGTVNLGCGALSTDKR
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCCCCEEEECCCCEEEECCCCCCCCCC
PAKINTKKLLSFYAGQRRKAWQLGPEHDVASALLPMGGAVSNVAGANWMLIGDSAACVNP
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCEEEEEECCHHCCCC
LNGEGIDYGLETAAMAVDTLVENPKRDLTLVWPHRLRDAYGETFMLARTAARLLTYPQFL
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCHHHHHHHHHHHHCCHHHH
PMAGPLAFRGPLQKAIMPAAARLMGNLITEEDKDLLARGWQAAGSAISWARKGSPLWDST
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
SSLV
CCCC
>Mature Secondary Structure 
GTGWNGSAATHSSLPLVIECGFILSVNPVKWTKSFLFNRSRRKALEAPWVSLLALRTET
CCCCCCCCCCCCCCCEEEECCEEEECCCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHH
MGFVSTTFDVLIIGAGPSGASAAVHAARAGLQTLLIDASSFPRDKTCGDGLTPRAIHQLE
HHHHEEEEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
LLGVADQVTGDYFNKGLKLHGFGGSVEAPWPETYFTNKGSAMSRMEFDDLLFRLAKSHEE
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCCHHHHCCHHHHHHHHHHCCHH
VTTWENASAQDPILRGNFLEGVVINHAGQEKTVKAKHVIIADGVRSPFGKKLGRQWHRDE
HHCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCHHH
VYGIAARAYCETPLSDEPWIHSHVELRDEDGVVQPGYGWIFPLGNGTVNLGCGALSTDKR
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEECCCCCEEEECCCCEEEECCCCCCCCCC
PAKINTKKLLSFYAGQRRKAWQLGPEHDVASALLPMGGAVSNVAGANWMLIGDSAACVNP
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCEEEEEECCHHCCCC
LNGEGIDYGLETAAMAVDTLVENPKRDLTLVWPHRLRDAYGETFMLARTAARLLTYPQFL
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCHHHHHHHHHHHHCCHHHH
PMAGPLAFRGPLQKAIMPAAARLMGNLITEEDKDLLARGWQAAGSAISWARKGSPLWDST
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
SSLV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA