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The map label for this gene is rfbC [H]

Identifier: 145294461

GI number: 145294461

Start: 453826

End: 455178

Strand: Reverse

Name: rfbC [H]

Synonym: cgR_0416

Alternate gene names: 145294461

Gene position: 455178-453826 (Counterclockwise)

Preceding gene: 145294462

Following gene: 145294460

Centisome position: 13.73

GC content: 59.5

Gene sequence:

>1353_bases
ATGTTTAACAAAGAACTCACCTCGCGCGACACCGACATCGAAGGTCTGCTGGTTTTCGATTTCCCCGTCCACGGCGACAA
CCGCGGCTGGTTCAAGGAAAATTGGCAGCGCACCAAGATGACCAACCTGGGTCTGCCTGATTTCGGCCCCGTCCAAAACA
ACATGAGCTACAACGCCACCGCCGGCACCACTCGCGGTATGCACGCTGAGCCGTGGGATAAATTTGTGTCCGTCGCGGTG
GGTTCCGTTTTCGGAGCTTGGGTGGATCTGCGCGCGGGCTCGAGCACGTACGGTAACGTCGTAACGCAAAAAATTACCCC
TGACGTGGGAGTTTACGTCCCGCGTGGTGTGGCAAACGGCTTCCAGGCGCTCGAGGACGGCACGCTGTACACCTACCTCG
TCAACGATCATTGGTCCCCCGACGCGCATTACGCCAACGTCAACCTCAACATGATCGACTGGCCGCTGCCCATCACCGAG
ATCTCCGAAAAAGATAAAAAACATCCCACGCTTGATCACGCCACCCCCCTGCCCGCCCGCCAGGTTCTAGTGGTCGGCGC
CGGCGGACAACTGGGAACCGCGCTACGCGCGCAGTTCCCAGACGCGGAATTTGTCACGCGCGAGGAACTCGATATCACCT
CAGATCTCACCGGGGCTCGTGCCTGGAAGCAGTACTCCACCATCATCAACGCCGCCGCCTACACTGCCGTTGACCAGGCA
GAACACGACCGCGCAGCGGCGTGGGCGATCAATGCCACTGCCGTGGCGAACTTGGCGACCATCGCGCGCGAAAACAACCT
CACCCTCGTGCACGTGTCCTCAGATTATGTCTTCGACGGTGCGGCCGAATCCTACGATGAAAACGCACCATTTTCCCCGC
TGGGTGTTTATGGACAGTCCAAAGCAGCCGGCGATATTGCAGCTGCGACCGCACCGCGCCACTACATTGTGCGCACCAGC
TGGGTCATTGGCGATGGCAATAATTTTGTCCGCACCATGAAATCCCTCGACGAACGCGGCATCGCACCTTCGGTTGTCGA
CGACCAAATCGGCCGCCTAACCTTCACCGAAGACATCGCAGCCGGCATCGCGCACCTTTTGGAAGTGGGTGCAGCATATG
GCACCTACAACCTCACCAACACCGGCGAACCCGCAAGCTGGGCCGATGTTGCCCGCGCAGTGTTCTCCGACCCCAGCAAG
GTCACCGGAGTGAGCACCGCGGAGTACTTCGCCGACAAAGACGCAGCACCCCGCCCACTGCGCTCCGTGCTGAATCTAGG
CAAGATCGAAGCAACAGGATTTAGCGCACCCACCTGGCAAACCCGCCTCAACAACTACCTCAAGGAGCTGTAA

Upstream 100 bases:

>100_bases
AAGGCCTAGAGCAGACCATCGATTGGTACCGCGAAAACGAGGCCTGGTGGCGCGGCACCAAGGACAACGTCGAAGCAACC
TACGCAAAGCAAGGCCAATA

Downstream 100 bases:

>100_bases
ATGAAAGGCATCATCCTCGCAGGCGGCTCCGGCACCCGGCTCTACCCCATCACCAAGGGCATCTCCAAGCAACTCATGCC
CATCTACGACAAGCCGATGG

Product: hypothetical protein

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MFNKELTSRDTDIEGLLVFDFPVHGDNRGWFKENWQRTKMTNLGLPDFGPVQNNMSYNATAGTTRGMHAEPWDKFVSVAV
GSVFGAWVDLRAGSSTYGNVVTQKITPDVGVYVPRGVANGFQALEDGTLYTYLVNDHWSPDAHYANVNLNMIDWPLPITE
ISEKDKKHPTLDHATPLPARQVLVVGAGGQLGTALRAQFPDAEFVTREELDITSDLTGARAWKQYSTIINAAAYTAVDQA
EHDRAAAWAINATAVANLATIARENNLTLVHVSSDYVFDGAAESYDENAPFSPLGVYGQSKAAGDIAAATAPRHYIVRTS
WVIGDGNNFVRTMKSLDERGIAPSVVDDQIGRLTFTEDIAAGIAHLLEVGAAYGTYNLTNTGEPASWADVARAVFSDPSK
VTGVSTAEYFADKDAAPRPLRSVLNLGKIEATGFSAPTWQTRLNNYLKEL

Sequences:

>Translated_450_residues
MFNKELTSRDTDIEGLLVFDFPVHGDNRGWFKENWQRTKMTNLGLPDFGPVQNNMSYNATAGTTRGMHAEPWDKFVSVAV
GSVFGAWVDLRAGSSTYGNVVTQKITPDVGVYVPRGVANGFQALEDGTLYTYLVNDHWSPDAHYANVNLNMIDWPLPITE
ISEKDKKHPTLDHATPLPARQVLVVGAGGQLGTALRAQFPDAEFVTREELDITSDLTGARAWKQYSTIINAAAYTAVDQA
EHDRAAAWAINATAVANLATIARENNLTLVHVSSDYVFDGAAESYDENAPFSPLGVYGQSKAAGDIAAATAPRHYIVRTS
WVIGDGNNFVRTMKSLDERGIAPSVVDDQIGRLTFTEDIAAGIAHLLEVGAAYGTYNLTNTGEPASWADVARAVFSDPSK
VTGVSTAEYFADKDAAPRPLRSVLNLGKIEATGFSAPTWQTRLNNYLKEL
>Mature_450_residues
MFNKELTSRDTDIEGLLVFDFPVHGDNRGWFKENWQRTKMTNLGLPDFGPVQNNMSYNATAGTTRGMHAEPWDKFVSVAV
GSVFGAWVDLRAGSSTYGNVVTQKITPDVGVYVPRGVANGFQALEDGTLYTYLVNDHWSPDAHYANVNLNMIDWPLPITE
ISEKDKKHPTLDHATPLPARQVLVVGAGGQLGTALRAQFPDAEFVTREELDITSDLTGARAWKQYSTIINAAAYTAVDQA
EHDRAAAWAINATAVANLATIARENNLTLVHVSSDYVFDGAAESYDENAPFSPLGVYGQSKAAGDIAAATAPRHYIVRTS
WVIGDGNNFVRTMKSLDERGIAPSVVDDQIGRLTFTEDIAAGIAHLLEVGAAYGTYNLTNTGEPASWADVARAVFSDPSK
VTGVSTAEYFADKDAAPRPLRSVLNLGKIEATGFSAPTWQTRLNNYLKEL

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788352, Length=295, Percent_Identity=33.5593220338983, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788350, Length=178, Percent_Identity=31.4606741573034, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 48894; Mature: 48894

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKELTSRDTDIEGLLVFDFPVHGDNRGWFKENWQRTKMTNLGLPDFGPVQNNMSYNAT
CCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCC
AGTTRGMHAEPWDKFVSVAVGSVFGAWVDLRAGSSTYGNVVTQKITPDVGVYVPRGVANG
CCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCCCEEECCCHHHH
FQALEDGTLYTYLVNDHWSPDAHYANVNLNMIDWPLPITEISEKDKKHPTLDHATPLPAR
HHHHCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCC
QVLVVGAGGQLGTALRAQFPDAEFVTREELDITSDLTGARAWKQYSTIINAAAYTAVDQA
EEEEEECCCCCCHHHHHCCCCCHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EHDRAAAWAINATAVANLATIARENNLTLVHVSSDYVFDGAAESYDENAPFSPLGVYGQS
CCCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCEEECCCHHCCCCCCCCCCCCCCCCC
KAAGDIAAATAPRHYIVRTSWVIGDGNNFVRTMKSLDERGIAPSVVDDQIGRLTFTEDIA
CCCCCHHHCCCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEHHHHH
AGIAHLLEVGAAYGTYNLTNTGEPASWADVARAVFSDPSKVTGVSTAEYFADKDAAPRPL
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHH
RSVLNLGKIEATGFSAPTWQTRLNNYLKEL
HHHHCCCCEEECCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MFNKELTSRDTDIEGLLVFDFPVHGDNRGWFKENWQRTKMTNLGLPDFGPVQNNMSYNAT
CCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCCCC
AGTTRGMHAEPWDKFVSVAVGSVFGAWVDLRAGSSTYGNVVTQKITPDVGVYVPRGVANG
CCCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEECCCCCCEEECCCHHHH
FQALEDGTLYTYLVNDHWSPDAHYANVNLNMIDWPLPITEISEKDKKHPTLDHATPLPAR
HHHHCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCC
QVLVVGAGGQLGTALRAQFPDAEFVTREELDITSDLTGARAWKQYSTIINAAAYTAVDQA
EEEEEECCCCCCHHHHHCCCCCHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EHDRAAAWAINATAVANLATIARENNLTLVHVSSDYVFDGAAESYDENAPFSPLGVYGQS
CCCCCEEEEECHHHHHHHHHHHCCCCEEEEEECCCEEECCCHHCCCCCCCCCCCCCCCCC
KAAGDIAAATAPRHYIVRTSWVIGDGNNFVRTMKSLDERGIAPSVVDDQIGRLTFTEDIA
CCCCCHHHCCCCCEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEHHHHH
AGIAHLLEVGAAYGTYNLTNTGEPASWADVARAVFSDPSKVTGVSTAEYFADKDAAPRPL
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHH
RSVLNLGKIEATGFSAPTWQTRLNNYLKEL
HHHHCCCCEEECCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA