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The map label for this gene is mdcB [H]

Identifier: 145294401

GI number: 145294401

Start: 391692

End: 392549

Strand: Reverse

Name: mdcB [H]

Synonym: cgR_0356

Alternate gene names: 145294401

Gene position: 392549-391692 (Counterclockwise)

Preceding gene: 145294402

Following gene: 145294400

Centisome position: 11.84

GC content: 50.58

Gene sequence:

>858_bases
ATGCACAACACTGTTAAAGTTCAACAAGCACCAATTGGCCGTTTAGCTACACAGGCTTTATTGGCTGAGGTTAATCTTCC
TCATAAACCAGGTTTGGTTGGCCCTGATGGTTCTCGCGGACACCAGGACATGGATATCGAGCTGATGCGGAAATCAGCGA
AGGTGTTGGAGCCAACGTTTTCAGAGCTTGCAGAAGCTGGCAAGACAATTGAGCTTGGTCAAGAGCTGCGCGATGAGATC
GGCAAGATTGGTCGGCGTGGTGAAGCCACAATGATGAACGCAACTGGCGGGGTAAATACTCACCGCGGGGCGATCTGGAA
TGTGGGGCTTTTAGTCACTGCTGCCTCAGGTTTGATGACACAGGAAGATCAGCCATTCACCGCTTTTTCCATTACACAGC
GTGCAGGCTCTCTGGCATCCATTCCCGATTCTTTTATTGATAGTTCTCCACGACCAGGGGCAACTGCGAGGAAGAAGTAC
AAAGTGGGAGGTGCCGTATCGGAAGCAGCCTCAGGTTTTCCTCATGTCATCGCCATCTTGCAGGCCATGGGCTTTTATGC
AGGCAATTTCACTCCGTCTCGTGAGCTGCAAATCAAAGGATTAATAACGTGTATGAGCAGCCTTGATGACACGTGTATTT
TGCACCGGGGCGGCGCCGAAGCTTTAGCTTTCGTGCATGGGTGGGCCACAGATTTATTGGTGGAAAGCCCACCGAATGAG
GGGTTGGACGTCGAAAAGCTATCTGCTTTTGATCAACACCTGACCAACCGCAACCTTTCCCCGGGCGGCAGTGCGGATCT
GCTTGCTGGCGCCTTATTTTTAACCTCGATTTTTGGAGAATCTCATGCAAATCATTAA

Upstream 100 bases:

>100_bases
CAAGTCGCACATTGCTTGCTGCTCATTCCATGGAATCACTTGTCGAATGGTCCGGCGGATTGTATGAGCCTCCAGCCAAG
TTCAAGAGTAGGTAAAAATG

Downstream 100 bases:

>100_bases
TGAAACTTTTCCTGCAACTATCCCTTTTCAACACGATATTCACGTTGGCGTCGTGGGCTCGGGTGATATGGAAATTCTGA
TTTCTGCACCCCGCAATGCT

Product: hypothetical protein

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MHNTVKVQQAPIGRLATQALLAEVNLPHKPGLVGPDGSRGHQDMDIELMRKSAKVLEPTFSELAEAGKTIELGQELRDEI
GKIGRRGEATMMNATGGVNTHRGAIWNVGLLVTAASGLMTQEDQPFTAFSITQRAGSLASIPDSFIDSSPRPGATARKKY
KVGGAVSEAASGFPHVIAILQAMGFYAGNFTPSRELQIKGLITCMSSLDDTCILHRGGAEALAFVHGWATDLLVESPPNE
GLDVEKLSAFDQHLTNRNLSPGGSADLLAGALFLTSIFGESHANH

Sequences:

>Translated_285_residues
MHNTVKVQQAPIGRLATQALLAEVNLPHKPGLVGPDGSRGHQDMDIELMRKSAKVLEPTFSELAEAGKTIELGQELRDEI
GKIGRRGEATMMNATGGVNTHRGAIWNVGLLVTAASGLMTQEDQPFTAFSITQRAGSLASIPDSFIDSSPRPGATARKKY
KVGGAVSEAASGFPHVIAILQAMGFYAGNFTPSRELQIKGLITCMSSLDDTCILHRGGAEALAFVHGWATDLLVESPPNE
GLDVEKLSAFDQHLTNRNLSPGGSADLLAGALFLTSIFGESHANH
>Mature_285_residues
MHNTVKVQQAPIGRLATQALLAEVNLPHKPGLVGPDGSRGHQDMDIELMRKSAKVLEPTFSELAEAGKTIELGQELRDEI
GKIGRRGEATMMNATGGVNTHRGAIWNVGLLVTAASGLMTQEDQPFTAFSITQRAGSLASIPDSFIDSSPRPGATARKKY
KVGGAVSEAASGFPHVIAILQAMGFYAGNFTPSRELQIKGLITCMSSLDDTCILHRGGAEALAFVHGWATDLLVESPPNE
GLDVEKLSAFDQHLTNRNLSPGGSADLLAGALFLTSIFGESHANH

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=271, Percent_Identity=33.210332103321, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 30177; Mature: 30177

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNTVKVQQAPIGRLATQALLAEVNLPHKPGLVGPDGSRGHQDMDIELMRKSAKVLEPTF
CCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHH
SELAEAGKTIELGQELRDEIGKIGRRGEATMMNATGGVNTHRGAIWNVGLLVTAASGLMT
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
QEDQPFTAFSITQRAGSLASIPDSFIDSSPRPGATARKKYKVGGAVSEAASGFPHVIAIL
CCCCCCCHHHHHHHCCCHHCCCHHHHCCCCCCCCCHHHHEECCCHHHHHHCCCHHHHHHH
QAMGFYAGNFTPSRELQIKGLITCMSSLDDTCILHRGGAEALAFVHGWATDLLVESPPNE
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEECCCCC
GLDVEKLSAFDQHLTNRNLSPGGSADLLAGALFLTSIFGESHANH
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHNTVKVQQAPIGRLATQALLAEVNLPHKPGLVGPDGSRGHQDMDIELMRKSAKVLEPTF
CCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHH
SELAEAGKTIELGQELRDEIGKIGRRGEATMMNATGGVNTHRGAIWNVGLLVTAASGLMT
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCC
QEDQPFTAFSITQRAGSLASIPDSFIDSSPRPGATARKKYKVGGAVSEAASGFPHVIAIL
CCCCCCCHHHHHHHCCCHHCCCHHHHCCCCCCCCCHHHHEECCCHHHHHHCCCHHHHHHH
QAMGFYAGNFTPSRELQIKGLITCMSSLDDTCILHRGGAEALAFVHGWATDLLVESPPNE
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEECCCCC
GLDVEKLSAFDQHLTNRNLSPGGSADLLAGALFLTSIFGESHANH
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA