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The map label for this gene is lrp [H]

Identifier: 145294379

GI number: 145294379

Start: 374403

End: 374867

Strand: Reverse

Name: lrp [H]

Synonym: cgR_0334

Alternate gene names: 145294379

Gene position: 374867-374403 (Counterclockwise)

Preceding gene: 145294382

Following gene: 145294376

Centisome position: 11.31

GC content: 49.89

Gene sequence:

>465_bases
GTGCAATATATGAAGCTAGATTCCATTGATCGCGCAATTATTGCGGAGCTTAGCGCGAATGCGCGCATCTCAAATCTCGC
ACTGGCTGACAAGGTGCATCTCACTCCGGGACCTTGCTTGAGGAGGGTGCAGCGTTTGGAAGCCGAAGGAATCATTTTGG
GCTACAGCGCGGACATTCACCCTGCGGTGATGAATCGTGGATTTGAGGTGACCGTGGATGTCACTCTCAGCAACTTCGAC
CGCTCCACTGTAGACAATTTTGAAAGCTCCGTTGCGCAGCATGATGAAGTACTGGAGTTGCACAGGCTTTTTGGTTCGCC
AGATTATTTTGTTCGCATCGGCGTTGCTGATTTGGAGGCGTATGAGCAATTTTTGTCCAATCACATTCAAACCGTGCCAG
GAATTGCAAAGATCTCATCACGTTTTGCTATGAAAGTGGTGAAACCAGCTCGCCCCCAGGTGTGA

Upstream 100 bases:

>100_bases
TCCAGGCTTGAATGAATCTCTTGCGTTTTTTGCACACTACAATCATCACACAATTGCCGGATAGTTTTGTTGCCAGTTTG
CACACCTCAACTAGGCTATT

Downstream 100 bases:

>100_bases
AGCATGTATTTTGGAGCATGAATCTTTTTCATCTAGTGAAGGACTGATCCCATGCGTATGAAATCAATCGCAGCAATTGC
AATCGCTACCGCCGCCCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MQYMKLDSIDRAIIAELSANARISNLALADKVHLTPGPCLRRVQRLEAEGIILGYSADIHPAVMNRGFEVTVDVTLSNFD
RSTVDNFESSVAQHDEVLELHRLFGSPDYFVRIGVADLEAYEQFLSNHIQTVPGIAKISSRFAMKVVKPARPQV

Sequences:

>Translated_154_residues
MQYMKLDSIDRAIIAELSANARISNLALADKVHLTPGPCLRRVQRLEAEGIILGYSADIHPAVMNRGFEVTVDVTLSNFD
RSTVDNFESSVAQHDEVLELHRLFGSPDYFVRIGVADLEAYEQFLSNHIQTVPGIAKISSRFAMKVVKPARPQV
>Mature_154_residues
MQYMKLDSIDRAIIAELSANARISNLALADKVHLTPGPCLRRVQRLEAEGIILGYSADIHPAVMNRGFEVTVDVTLSNFD
RSTVDNFESSVAQHDEVLELHRLFGSPDYFVRIGVADLEAYEQFLSNHIQTVPGIAKISSRFAMKVVKPARPQV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=145, Percent_Identity=35.8620689655172, Blast_Score=104, Evalue=2e-24,
Organism=Escherichia coli, GI87081742, Length=143, Percent_Identity=34.965034965035, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17152; Mature: 17152

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYMKLDSIDRAIIAELSANARISNLALADKVHLTPGPCLRRVQRLEAEGIILGYSADIH
CCCCCCCCHHHHHHHHHCCCCEEHHEEEECEEECCCCHHHHHHHHHCCCCEEEEECCCCC
PAVMNRGFEVTVDVTLSNFDRSTVDNFESSVAQHDEVLELHRLFGSPDYFVRIGVADLEA
HHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHH
YEQFLSNHIQTVPGIAKISSRFAMKVVKPARPQV
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQYMKLDSIDRAIIAELSANARISNLALADKVHLTPGPCLRRVQRLEAEGIILGYSADIH
CCCCCCCCHHHHHHHHHCCCCEEHHEEEECEEECCCCHHHHHHHHHCCCCEEEEECCCCC
PAVMNRGFEVTVDVTLSNFDRSTVDNFESSVAQHDEVLELHRLFGSPDYFVRIGVADLEA
HHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHH
YEQFLSNHIQTVPGIAKISSRFAMKVVKPARPQV
HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]