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The map label for this gene is moaE2 [H]

Identifier: 145294336

GI number: 145294336

Start: 317211

End: 318398

Strand: Reverse

Name: moaE2 [H]

Synonym: cgR_0291

Alternate gene names: 145294336

Gene position: 318398-317211 (Counterclockwise)

Preceding gene: 145294337

Following gene: 145294335

Centisome position: 9.61

GC content: 55.72

Gene sequence:

>1188_bases
TTGATGTCTCGTTCGCCGGAGCAACATTTGGCAGAAATTTCCGCGCTGCTTCCCCCACAAAAGTCCACGTTCGTGAATCT
GCGCGAAGCGTTGGGACGCCGCACGTTTACAGCGGTCACTGCGCAGTGGGATTCGCCACGTTTTGATAATTCCCAAATGG
ATGGCTTCGCACTTGGCCCCTCACATTTAAACGGTGGCACCTTCGCAGTCGGTCCAACCATCCCCGCTGGTCATGATCCT
GATCAGTGGTACCCACGAGGCATCGAAAAAGACATCGCGCCGATTATGACGGGTGCGCGCCTTCCTAAAAACACCGCCGC
GATCATTCCTGTGGAGAAAACTACACCGGGAAATTTCGACGCCCCGCAGGTAGAAATCCCCGCCACCCCGCAAGGTCAGT
TCATACGGTTGCAGGGCTCGGATATTACTGCTGGCGACGAGATCATTCCAGGAGGTACGGAGCTTAACTCGATGCACATC
GGGGTGTTGGCTAGTCAGTCGATCAAGAGTATTGAAGTCGCAGCAAAGCCACGTGTCCTGATCATTACCGGCGGGTCTGA
AATTTCAGAACAGCACGGCCCCGCCACGATCCCTGATGCCAACGGCCCTCTGCTTCGTTCCCTGTGCGCCCGCAACAACA
TCGAGGTCATCGCAGGACTACACACCAACGACGATCCTGAACGACTCCGCTTTGAACTGGACAACGCCATTGACCAGTAC
CAACCAGATGCCATCATCACCTCTGGCGGTATCAGCCACGGAAAATTTGAGGTGTTTAGGCAGATCCTTGAAGGCTCCCC
GAACTCCTGGTTTGGGCATGTCGATCAGCAACCTGGCGGCCCACAAGGCATCTCCACTTTTGCTGAAACTCCTGTCATTT
CACTTCCCGGAAATCCGATTTCCACTTTGGTGAGTTTCACACTTTTCGTCGCGCCAGCGCTCAACCGCCAGCCGCTCCGC
CACCTCGATGCCCACATCACCGCTCCGGTCCAGGGCTTGCAAGACAACCGGGAACAATTCCTTCGCGGAACCATCAATTA
TGCCAACGGCAAGGTCCTCGCCACGCCTCTCCTCGGCACCAGTTCCCACCTGCTGGTTCAAGCTGCCACAGCCAACTGTC
TGATCAGGATCCCGGCGCGGACTACGGTGGAGGAAAACGACATCGTTAAGATCTACCCATTCAACTAA

Upstream 100 bases:

>100_bases
TAAAGCCTTGGGAGCGGTGATTATGCTTTTGGCTGTCTATGTCCTCATCATTGGAGCCATCGGAGCGTTACGATTGTTTT
CCAAGGTGAGAAAGGTTTAA

Downstream 100 bases:

>100_bases
CAGGAGTTAATTTAATGAGCAAGCTCACCCACGTTCGAGAAGACGGTTCCGCGCATATGGTGGATGTGACGGGCAAAAAT
GAAACGTCGAGAACTGCTGT

Product: hypothetical protein

Products: NA

Alternate protein names: MPT Mo-transferase 2 [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MMSRSPEQHLAEISALLPPQKSTFVNLREALGRRTFTAVTAQWDSPRFDNSQMDGFALGPSHLNGGTFAVGPTIPAGHDP
DQWYPRGIEKDIAPIMTGARLPKNTAAIIPVEKTTPGNFDAPQVEIPATPQGQFIRLQGSDITAGDEIIPGGTELNSMHI
GVLASQSIKSIEVAAKPRVLIITGGSEISEQHGPATIPDANGPLLRSLCARNNIEVIAGLHTNDDPERLRFELDNAIDQY
QPDAIITSGGISHGKFEVFRQILEGSPNSWFGHVDQQPGGPQGISTFAETPVISLPGNPISTLVSFTLFVAPALNRQPLR
HLDAHITAPVQGLQDNREQFLRGTINYANGKVLATPLLGTSSHLLVQAATANCLIRIPARTTVEENDIVKIYPFN

Sequences:

>Translated_395_residues
MMSRSPEQHLAEISALLPPQKSTFVNLREALGRRTFTAVTAQWDSPRFDNSQMDGFALGPSHLNGGTFAVGPTIPAGHDP
DQWYPRGIEKDIAPIMTGARLPKNTAAIIPVEKTTPGNFDAPQVEIPATPQGQFIRLQGSDITAGDEIIPGGTELNSMHI
GVLASQSIKSIEVAAKPRVLIITGGSEISEQHGPATIPDANGPLLRSLCARNNIEVIAGLHTNDDPERLRFELDNAIDQY
QPDAIITSGGISHGKFEVFRQILEGSPNSWFGHVDQQPGGPQGISTFAETPVISLPGNPISTLVSFTLFVAPALNRQPLR
HLDAHITAPVQGLQDNREQFLRGTINYANGKVLATPLLGTSSHLLVQAATANCLIRIPARTTVEENDIVKIYPFN
>Mature_395_residues
MMSRSPEQHLAEISALLPPQKSTFVNLREALGRRTFTAVTAQWDSPRFDNSQMDGFALGPSHLNGGTFAVGPTIPAGHDP
DQWYPRGIEKDIAPIMTGARLPKNTAAIIPVEKTTPGNFDAPQVEIPATPQGQFIRLQGSDITAGDEIIPGGTELNSMHI
GVLASQSIKSIEVAAKPRVLIITGGSEISEQHGPATIPDANGPLLRSLCARNNIEVIAGLHTNDDPERLRFELDNAIDQY
QPDAIITSGGISHGKFEVFRQILEGSPNSWFGHVDQQPGGPQGISTFAETPVISLPGNPISTLVSFTLFVAPALNRQPLR
HLDAHITAPVQGLQDNREQFLRGTINYANGKVLATPLLGTSSHLLVQAATANCLIRIPARTTVEENDIVKIYPFN

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=327, Percent_Identity=28.7461773700306, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI10880983, Length=327, Percent_Identity=28.7461773700306, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1787049, Length=380, Percent_Identity=28.6842105263158, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25147659, Length=337, Percent_Identity=29.9703264094956, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562606, Length=384, Percent_Identity=24.4791666666667, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI17136978, Length=354, Percent_Identity=27.683615819209, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638841, Length=354, Percent_Identity=27.683615819209, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 42516; Mature: 42516

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSRSPEQHLAEISALLPPQKSTFVNLREALGRRTFTAVTAQWDSPRFDNSQMDGFALGP
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEECC
SHLNGGTFAVGPTIPAGHDPDQWYPRGIEKDIAPIMTGARLPKNTAAIIPVEKTTPGNFD
CCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
APQVEIPATPQGQFIRLQGSDITAGDEIIPGGTELNSMHIGVLASQSIKSIEVAAKPRVL
CCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEE
IITGGSEISEQHGPATIPDANGPLLRSLCARNNIEVIAGLHTNDDPERLRFELDNAIDQY
EEECCCHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHC
QPDAIITSGGISHGKFEVFRQILEGSPNSWFGHVDQQPGGPQGISTFAETPVISLPGNPI
CCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEECCCCHH
STLVSFTLFVAPALNRQPLRHLDAHITAPVQGLQDNREQFLRGTINYANGKVLATPLLGT
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCEEEEEECCCC
SSHLLVQAATANCLIRIPARTTVEENDIVKIYPFN
CCCEEEEEECCCEEEECCCCCEECCCCEEEEEECC
>Mature Secondary Structure
MMSRSPEQHLAEISALLPPQKSTFVNLREALGRRTFTAVTAQWDSPRFDNSQMDGFALGP
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEECC
SHLNGGTFAVGPTIPAGHDPDQWYPRGIEKDIAPIMTGARLPKNTAAIIPVEKTTPGNFD
CCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCC
APQVEIPATPQGQFIRLQGSDITAGDEIIPGGTELNSMHIGVLASQSIKSIEVAAKPRVL
CCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEE
IITGGSEISEQHGPATIPDANGPLLRSLCARNNIEVIAGLHTNDDPERLRFELDNAIDQY
EEECCCHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHC
QPDAIITSGGISHGKFEVFRQILEGSPNSWFGHVDQQPGGPQGISTFAETPVISLPGNPI
CCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCEEECCCCHH
STLVSFTLFVAPALNRQPLRHLDAHITAPVQGLQDNREQFLRGTINYANGKVLATPLLGT
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCEEEEEECCCC
SSHLLVQAATANCLIRIPARTTVEENDIVKIYPFN
CCCEEEEEECCCEEEECCCCCEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]