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The map label for this gene is moaC

Identifier: 145294335

GI number: 145294335

Start: 316726

End: 317196

Strand: Reverse

Name: moaC

Synonym: cgR_0290

Alternate gene names: 145294335

Gene position: 317196-316726 (Counterclockwise)

Preceding gene: 145294336

Following gene: 145294334

Centisome position: 9.57

GC content: 54.35

Gene sequence:

>471_bases
ATGAGCAAGCTCACCCACGTTCGAGAAGACGGTTCCGCGCATATGGTGGATGTGACGGGCAAAAATGAAACGTCGAGAAC
TGCTGTTGCCGAAGGGTTTGTGAAGATGAGGGGGGACGTCGTAAAGCAGCTTTTTAGCGCTGGCCTGCCTAAAGGTGACG
CGTTACCTGTAGCGCGGATTGCGGGTATCATGGGCGCGAAGAAGACGCCGGACATTATCCCTTTATGCCACCCGTTGCCG
CTGGGCAAAATTACTGTGGATTTTTTTGAGCTTGCTGATGGTGTTCGGATTGAGGCTTCGGTGAAAACGCGTGGGGTTAC
TGGTGTGGAAATGGAGGCGTTGACGGCCGTGAGCACTGCGGCGCTGACGGTGTACGACATGATCAAGGCTGTGGACAAGA
TGGCCGTGATTGATGGCATTCGTGTGCTGTCGAAAACTGGCGGTAAATCTGGGGATTGGTCCGTGCAGTGA

Upstream 100 bases:

>100_bases
CTGCCACAGCCAACTGTCTGATCAGGATCCCGGCGCGGACTACGGTGGAGGAAAACGACATCGTTAAGATCTACCCATTC
AACTAACAGGAGTTAATTTA

Downstream 100 bases:

>100_bases
CAGCTCTGGTTATCGTTGCGTCCACTCGCGCCGCTGCGGGGGTGTATGAGGATCGCTCTGGCCCAATTTTGGTGTCGTGG
CTGCGTGCAAAAGGTTTTGA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSKLTHVREDGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARIAGIMGAKKTPDIIPLCHPLP
LGKITVDFFELADGVRIEASVKTRGVTGVEMEALTAVSTAALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ

Sequences:

>Translated_156_residues
MSKLTHVREDGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARIAGIMGAKKTPDIIPLCHPLP
LGKITVDFFELADGVRIEASVKTRGVTGVEMEALTAVSTAALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ
>Mature_155_residues
SKLTHVREDGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARIAGIMGAKKTPDIIPLCHPLPL
GKITVDFFELADGVRIEASVKTRGVTGVEMEALTAVSTAALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=53.7974683544304, Blast_Score=159, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=41.6107382550336, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=51.3333333333333, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28574492, Length=138, Percent_Identity=52.8985507246377, Blast_Score=129, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_CORGB (A4QAK7)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001137156.1
- ProteinModelPortal:   A4QAK7
- SMR:   A4QAK7
- STRING:   A4QAK7
- GeneID:   4994465
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_0290
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16465; Mature: 16334

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLTHVREDGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARI
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AGIMGAKKTPDIIPLCHPLPLGKITVDFFELADGVRIEASVKTRGVTGVEMEALTAVSTA
HHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHH
ALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SKLTHVREDGSAHMVDVTGKNETSRTAVAEGFVKMRGDVVKQLFSAGLPKGDALPVARI
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AGIMGAKKTPDIIPLCHPLPLGKITVDFFELADGVRIEASVKTRGVTGVEMEALTAVSTA
HHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHH
ALTVYDMIKAVDKMAVIDGIRVLSKTGGKSGDWSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA