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The map label for this gene is agaR [H]

Identifier: 145294224

GI number: 145294224

Start: 198981

End: 199769

Strand: Reverse

Name: agaR [H]

Synonym: cgR_0180

Alternate gene names: 145294224

Gene position: 199769-198981 (Counterclockwise)

Preceding gene: 145294228

Following gene: 145294223

Centisome position: 6.03

GC content: 61.22

Gene sequence:

>789_bases
GTGGCGGATTCTGATCATATGGAACGCGAACAACGGCACAAAGTGATCATGCGGACGGTCGACCGGCCCGGAATCACCCG
CATTGATGCCCTCACCGAACTGACTGGGGTGTCTGCGGTGACCATCCGCCGAGATCTCGCCGATCTGGAGCAAGCAGGCT
TTCTCGCACGCACCCACGGCGGAGCGAAACGAGTCCTCAAACGTGGCGCTCCGCAACCGTTTGCCGTGCGCCGTGCCGAG
GATCGGGCCGCCAAACACATCCTGGCGCAGGCCACTGCCCGACTAATTGCCGATGATGAAGCAGTGATTATCGACAACGG
CACCACCTGCCAGGCAGTGGCCCAGGAGTTGGCAGGGCGTCCTATCACGGCGTTGTGCCTGTCTCTACATTCAGCGGTCG
CCCTGGGAAGCCGGGCCGGGACACACATTTTCATCCCCGGTGGACCCGTGGAAAACGACACCCTTGCCTTATCCGGGCCG
GCAGTAATTACCGCGGTACGAGACTTCTCCGCTGACGCAGTGATCCTCGGATCCTGCTCCACATCGTTAAGCCACGGATT
AGCCACCACCACCTACGACGACGCTGAGAACAAACGCGCGGCCATCAATGCTGCCACCCGACGAATCCTCGTGGTGGCCG
CCCGCAAACTCAACCACGTCTCCACATTCCGCTTCGCAGACGTCACAGACCTGCACCAGCTGGTTACTACCTCCGATGCC
CCGAGGGAGATCCTCGCCGAGATCCGGGACCTCGGCGTTCAAGTCATTACTGTTCCCGCTCCTGACTAG

Upstream 100 bases:

>100_bases
TATTGGGATGCCCGATTCTCTGCACGGTCTCCGATTTAGAATATAAAGGCCTTATAGGCTGTATTTTTACGGAGAACGTG
GGGTTGACATCCGCTGGAAA

Downstream 100 bases:

>100_bases
TGGCATGGCCAGCTAAGAAATTCGAACCGACTTCATTGATCCTTGGCTCGACTCGCTCAGCGACGAAGTTTATGACGCAG
TACTTGCCGCCATTGAATAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MADSDHMEREQRHKVIMRTVDRPGITRIDALTELTGVSAVTIRRDLADLEQAGFLARTHGGAKRVLKRGAPQPFAVRRAE
DRAAKHILAQATARLIADDEAVIIDNGTTCQAVAQELAGRPITALCLSLHSAVALGSRAGTHIFIPGGPVENDTLALSGP
AVITAVRDFSADAVILGSCSTSLSHGLATTTYDDAENKRAAINAATRRILVVAARKLNHVSTFRFADVTDLHQLVTTSDA
PREILAEIRDLGVQVITVPAPD

Sequences:

>Translated_262_residues
MADSDHMEREQRHKVIMRTVDRPGITRIDALTELTGVSAVTIRRDLADLEQAGFLARTHGGAKRVLKRGAPQPFAVRRAE
DRAAKHILAQATARLIADDEAVIIDNGTTCQAVAQELAGRPITALCLSLHSAVALGSRAGTHIFIPGGPVENDTLALSGP
AVITAVRDFSADAVILGSCSTSLSHGLATTTYDDAENKRAAINAATRRILVVAARKLNHVSTFRFADVTDLHQLVTTSDA
PREILAEIRDLGVQVITVPAPD
>Mature_261_residues
ADSDHMEREQRHKVIMRTVDRPGITRIDALTELTGVSAVTIRRDLADLEQAGFLARTHGGAKRVLKRGAPQPFAVRRAED
RAAKHILAQATARLIADDEAVIIDNGTTCQAVAQELAGRPITALCLSLHSAVALGSRAGTHIFIPGGPVENDTLALSGPA
VITAVRDFSADAVILGSCSTSLSHGLATTTYDDAENKRAAINAATRRILVVAARKLNHVSTFRFADVTDLHQLVTTSDAP
REILAEIRDLGVQVITVPAPD

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=255, Percent_Identity=29.0196078431373, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789829, Length=250, Percent_Identity=26.4, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=28.3261802575107, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=22.8346456692913, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=25.296442687747, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=26.4957264957265, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789170, Length=210, Percent_Identity=24.2857142857143, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27927; Mature: 27796

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSDHMEREQRHKVIMRTVDRPGITRIDALTELTGVSAVTIRRDLADLEQAGFLARTHG
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCC
GAKRVLKRGAPQPFAVRRAEDRAAKHILAQATARLIADDEAVIIDNGTTCQAVAQELAGR
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCC
PITALCLSLHSAVALGSRAGTHIFIPGGPVENDTLALSGPAVITAVRDFSADAVILGSCS
CHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCEEEEEECCCCCCEEEEECCC
TSLSHGLATTTYDDAENKRAAINAATRRILVVAARKLNHVSTFRFADVTDLHQLVTTSDA
HHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHCCCC
PREILAEIRDLGVQVITVPAPD
HHHHHHHHHHCCEEEEEECCCC
>Mature Secondary Structure 
ADSDHMEREQRHKVIMRTVDRPGITRIDALTELTGVSAVTIRRDLADLEQAGFLARTHG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCC
GAKRVLKRGAPQPFAVRRAEDRAAKHILAQATARLIADDEAVIIDNGTTCQAVAQELAGR
CHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCC
PITALCLSLHSAVALGSRAGTHIFIPGGPVENDTLALSGPAVITAVRDFSADAVILGSCS
CHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEECCCEEEEEECCCCCCEEEEECCC
TSLSHGLATTTYDDAENKRAAINAATRRILVVAARKLNHVSTFRFADVTDLHQLVTTSDA
HHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHCCCC
PREILAEIRDLGVQVITVPAPD
HHHHHHHHHHCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]