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The map label for this gene is mnmG

Identifier: 138897066

GI number: 138897066

Start: 3544411

End: 3546300

Strand: Reverse

Name: mnmG

Synonym: GTNG_3439

Alternate gene names: 138897066

Gene position: 3546300-3544411 (Counterclockwise)

Preceding gene: 138897067

Following gene: 138897065

Centisome position: 99.89

GC content: 51.38

Gene sequence:

>1890_bases
ATGGAGTATCACGGAGGATCGTATGACGTCATCGTCATCGGTGCTGGTCATGCCGGCTGCGAGGCGGCTCTGGCGTCTGC
GCGCATCGGTGCGAAAACGCTCGTCATTACGCTTAACCTCGATATGATCGCATTTATGCCATGCAATCCGTCGATTGGCG
GCCCAGCGAAAGGGATCGTCGTGCGCGAAATCGATGCTCTCGGCGGAGAAATGGGGAAAAACATTGATAAAACATACATT
CAAATTCGGATGCTCAACACCGGCAAGGGGCCGGCTGTCCGCGCGTTGCGTGCGCAAGCGGACAAAGTGCTTTACCAGCG
GGAAATGAAAAAGACGCTCGAAAACCAGAAAAATTTGACGTTGCTGCAGGGGAAAGTCGAGCGGCTCATCGTCGAAGATG
GCGTCTGCAAAGGCGTCATTACGCAAACAGGAGCGCATTATTACGCCAAAGCGGTTGTCATTACGACTGGGACGTTTCTA
CGTGGGGAAATTATTATTGGCGATATTAAATATTCAAGCGGACCGAACAACCAGCAGCCGTCGATTAAGCTGTCTGAGCA
TTTAGAAGAGCTTGGGTTCGAGCTCGTTCGCTTCAAAACGGGAACGCCGCCGCGCGTTAACAGCCGGACAATTGACTACA
GCAAAACAGAAATTCAGCCGGGCGACGAGGAACCGCGGGCTTTTTCGTACGAAACGACGAAATACATCACCGACCAACTG
CCTTGCTGGCTGACGTATACGACAGAGGAAACTCATCGCATCATTGACGAAAACTTGCATTTGTCGCCGATGTACTCCGG
CATGATTAAAGGAACCGGACCGCGCTATTGTCCGTCGATCGAGGATAAAGTCGTCCGATTCCACGACAAACCGCGTCATC
AAATTTTCCTCGAGCCGGAAGGGCGGGAAACGGAAGAAGTGTACGTGCAAGGATTGTCGACAAGCTTGCCGGAACATATT
CAACGCAAGTTGCTTGAGACTATTCCTGGACTTGAGAAAGCGCAGCTTATGCGGGCTGGCTATGCGATCGAGTACGATGC
GATTGTGCCGACACAGTTATGGCCGACGTTGGAAACCAAGTTGGTGAAAAACTTATACACCGCTGGTCAAATTAACGGTA
CGTCCGGCTACGAAGAAGCGGCGGGTCAAGGCATTATGGCCGGCATTAACGCCGCCCATCGCGCGCTCGGCCGCGAGGAA
ATCATTTTAAGTCGTTCGGATGCCTATATCGGTGTCTTGATCGACGATTTAGTAACAAAAGGGACAAACGAGCCGTACCG
CTTGTTGACATCACGCGCTGAATATCGGCTGTTGCTCCGCCACGACAATGCTGATTTGCGCCTGACCGAGCTCGGCTATC
GGATCGGCCTTATTTCCGAAGAGAGGTACCAAGCGTTCTTGGCGAAAAAAGAGGCAATCGAACGGGAGAAAAAACGGTTG
CAAACGGTCATCATCAAACCGACGCCAGAAGTGCAGGAAGTGATCCGCCAAGCAGGGGGAAGCGAGCTGAAAGATGGCAT
CCGCGCTGCAGACTTGCTCCGGCGCCCAGAAATGACGTACGAACATATTCAAAAACTCGCGCCGGCTGACGAAGACATCG
CTCCAGAAGTGGCTGAGCAAGTTGAAATTCAAATCAAATATGAAGGGTATATTCAAAAATCGTTGCAAGAAGTTGAACGG
CTCAAAAAAATGGAAAACAAAAAAATTCCGGAAGATATCGATTACGACGCTATCCAAGGACTGGCGACCGAGGCGCGGCA
AAAGCTGAAACAAGTGCGCCCGCTCTCGATTGCCCAAGCATCGCGCATTTCGGGCGTCAATCCGGCCGATATTTCGATAT
TATTAGTGTATTTGGAACAAGGAAGAATCGCGCGCGTGTCGAATGAATAA

Upstream 100 bases:

>100_bases
GAGCTGCTTGGCGAAATCGTTGGCGATACAGTGCATGAAAGCCTGATTGATCAGCTGTTTGCCCAATTTTGTTTAGGAAA
ATAAACAAGGAGGAACCGAA

Downstream 100 bases:

>100_bases
ATCATGAGGGAAAGGATTGGCTTATGGAGGCGACACAATTTCAAGCCATGCTCGAAGAGAGGGGAATTTCCCTCTCTTCC
CAGGCGCTTGCACAGTTTGA

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 629; Mature: 629

Protein sequence:

>629_residues
MEYHGGSYDVIVIGAGHAGCEAALASARIGAKTLVITLNLDMIAFMPCNPSIGGPAKGIVVREIDALGGEMGKNIDKTYI
QIRMLNTGKGPAVRALRAQADKVLYQREMKKTLENQKNLTLLQGKVERLIVEDGVCKGVITQTGAHYYAKAVVITTGTFL
RGEIIIGDIKYSSGPNNQQPSIKLSEHLEELGFELVRFKTGTPPRVNSRTIDYSKTEIQPGDEEPRAFSYETTKYITDQL
PCWLTYTTEETHRIIDENLHLSPMYSGMIKGTGPRYCPSIEDKVVRFHDKPRHQIFLEPEGRETEEVYVQGLSTSLPEHI
QRKLLETIPGLEKAQLMRAGYAIEYDAIVPTQLWPTLETKLVKNLYTAGQINGTSGYEEAAGQGIMAGINAAHRALGREE
IILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTELGYRIGLISEERYQAFLAKKEAIEREKKRL
QTVIIKPTPEVQEVIRQAGGSELKDGIRAADLLRRPEMTYEHIQKLAPADEDIAPEVAEQVEIQIKYEGYIQKSLQEVER
LKKMENKKIPEDIDYDAIQGLATEARQKLKQVRPLSIAQASRISGVNPADISILLVYLEQGRIARVSNE

Sequences:

>Translated_629_residues
MEYHGGSYDVIVIGAGHAGCEAALASARIGAKTLVITLNLDMIAFMPCNPSIGGPAKGIVVREIDALGGEMGKNIDKTYI
QIRMLNTGKGPAVRALRAQADKVLYQREMKKTLENQKNLTLLQGKVERLIVEDGVCKGVITQTGAHYYAKAVVITTGTFL
RGEIIIGDIKYSSGPNNQQPSIKLSEHLEELGFELVRFKTGTPPRVNSRTIDYSKTEIQPGDEEPRAFSYETTKYITDQL
PCWLTYTTEETHRIIDENLHLSPMYSGMIKGTGPRYCPSIEDKVVRFHDKPRHQIFLEPEGRETEEVYVQGLSTSLPEHI
QRKLLETIPGLEKAQLMRAGYAIEYDAIVPTQLWPTLETKLVKNLYTAGQINGTSGYEEAAGQGIMAGINAAHRALGREE
IILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTELGYRIGLISEERYQAFLAKKEAIEREKKRL
QTVIIKPTPEVQEVIRQAGGSELKDGIRAADLLRRPEMTYEHIQKLAPADEDIAPEVAEQVEIQIKYEGYIQKSLQEVER
LKKMENKKIPEDIDYDAIQGLATEARQKLKQVRPLSIAQASRISGVNPADISILLVYLEQGRIARVSNE
>Mature_629_residues
MEYHGGSYDVIVIGAGHAGCEAALASARIGAKTLVITLNLDMIAFMPCNPSIGGPAKGIVVREIDALGGEMGKNIDKTYI
QIRMLNTGKGPAVRALRAQADKVLYQREMKKTLENQKNLTLLQGKVERLIVEDGVCKGVITQTGAHYYAKAVVITTGTFL
RGEIIIGDIKYSSGPNNQQPSIKLSEHLEELGFELVRFKTGTPPRVNSRTIDYSKTEIQPGDEEPRAFSYETTKYITDQL
PCWLTYTTEETHRIIDENLHLSPMYSGMIKGTGPRYCPSIEDKVVRFHDKPRHQIFLEPEGRETEEVYVQGLSTSLPEHI
QRKLLETIPGLEKAQLMRAGYAIEYDAIVPTQLWPTLETKLVKNLYTAGQINGTSGYEEAAGQGIMAGINAAHRALGREE
IILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTELGYRIGLISEERYQAFLAKKEAIEREKKRL
QTVIIKPTPEVQEVIRQAGGSELKDGIRAADLLRRPEMTYEHIQKLAPADEDIAPEVAEQVEIQIKYEGYIQKSLQEVER
LKKMENKKIPEDIDYDAIQGLATEARQKLKQVRPLSIAQASRISGVNPADISILLVYLEQGRIARVSNE

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=631, Percent_Identity=43.7400950871632, Blast_Score=474, Evalue=1e-134,
Organism=Homo sapiens, GI19882217, Length=656, Percent_Identity=42.0731707317073, Blast_Score=460, Evalue=1e-129,
Organism=Homo sapiens, GI183227703, Length=670, Percent_Identity=41.044776119403, Blast_Score=456, Evalue=1e-128,
Organism=Escherichia coli, GI2367273, Length=626, Percent_Identity=52.2364217252396, Blast_Score=636, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=624, Percent_Identity=41.3461538461538, Blast_Score=468, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6321202, Length=634, Percent_Identity=45.1104100946372, Blast_Score=496, Evalue=1e-141,
Organism=Drosophila melanogaster, GI24658174, Length=640, Percent_Identity=42.8125, Blast_Score=457, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_GEOTN (A4ITX0)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001127519.1
- ProteinModelPortal:   A4ITX0
- SMR:   A4ITX0
- STRING:   A4ITX0
- GeneID:   4968360
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_3439
- NMPDR:   fig|420246.5.peg.3285
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   A4ITX0
- ProtClustDB:   PRK05192
- BioCyc:   GTHE420246:GTNG_3439-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 70355; Mature: 70355

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: BINDING 126-126 BINDING 181-181 BINDING 370-370

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYHGGSYDVIVIGAGHAGCEAALASARIGAKTLVITLNLDMIAFMPCNPSIGGPAKGIV
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEEECCEEEEECCCCCCCCCCCCEE
VREIDALGGEMGKNIDKTYIQIRMLNTGKGPAVRALRAQADKVLYQREMKKTLENQKNLT
EEEHHHHCHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LLQGKVERLIVEDGVCKGVITQTGAHYYAKAVVITTGTFLRGEIIIGDIKYSSGPNNQQP
EEHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEEECCEEEEEEEEEEEEECCCCCCCCC
SIKLSEHLEELGFELVRFKTGTPPRVNSRTIDYSKTEIQPGDEEPRAFSYETTKYITDQL
CEEHHHHHHHHCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCEECCHHHHHHHCCC
PCWLTYTTEETHRIIDENLHLSPMYSGMIKGTGPRYCPSIEDKVVRFHDKPRHQIFLEPE
CEEEEECCCHHHHHHHCCCEECHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCC
GRETEEVYVQGLSTSLPEHIQRKLLETIPGLEKAQLMRAGYAIEYDAIVPTQLWPTLETK
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCHHCHHHHHH
LVKNLYTAGQINGTSGYEEAAGQGIMAGINAAHRALGREEIILSRSDAYIGVLIDDLVTK
HHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCHHEEEECCCCEEEEEHHHHHHC
GTNEPYRLLTSRAEYRLLLRHDNADLRLTELGYRIGLISEERYQAFLAKKEAIEREKKRL
CCCCCHHHHHCCCCEEEEEEECCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHE
QTVIIKPTPEVQEVIRQAGGSELKDGIRAADLLRRPEMTYEHIQKLAPADEDIAPEVAEQ
EEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHC
VEIQIKYEGYIQKSLQEVERLKKMENKKIPEDIDYDAIQGLATEARQKLKQVRPLSIAQA
EEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
SRISGVNPADISILLVYLEQGRIARVSNE
HHCCCCCCCCCEEEEEEECCCCEEECCCC
>Mature Secondary Structure
MEYHGGSYDVIVIGAGHAGCEAALASARIGAKTLVITLNLDMIAFMPCNPSIGGPAKGIV
CCCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEEEEECCEEEEECCCCCCCCCCCCEE
VREIDALGGEMGKNIDKTYIQIRMLNTGKGPAVRALRAQADKVLYQREMKKTLENQKNLT
EEEHHHHCHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LLQGKVERLIVEDGVCKGVITQTGAHYYAKAVVITTGTFLRGEIIIGDIKYSSGPNNQQP
EEHHHHHHHHHHCCCCCCHHHHCCCCCEEEEEEEEECCEEEEEEEEEEEEECCCCCCCCC
SIKLSEHLEELGFELVRFKTGTPPRVNSRTIDYSKTEIQPGDEEPRAFSYETTKYITDQL
CEEHHHHHHHHCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCEECCHHHHHHHCCC
PCWLTYTTEETHRIIDENLHLSPMYSGMIKGTGPRYCPSIEDKVVRFHDKPRHQIFLEPE
CEEEEECCCHHHHHHHCCCEECHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCC
GRETEEVYVQGLSTSLPEHIQRKLLETIPGLEKAQLMRAGYAIEYDAIVPTQLWPTLETK
CCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCCCCHHCHHHHHH
LVKNLYTAGQINGTSGYEEAAGQGIMAGINAAHRALGREEIILSRSDAYIGVLIDDLVTK
HHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCHHEEEECCCCEEEEEHHHHHHC
GTNEPYRLLTSRAEYRLLLRHDNADLRLTELGYRIGLISEERYQAFLAKKEAIEREKKRL
CCCCCHHHHHCCCCEEEEEEECCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHE
QTVIIKPTPEVQEVIRQAGGSELKDGIRAADLLRRPEMTYEHIQKLAPADEDIAPEVAEQ
EEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHC
VEIQIKYEGYIQKSLQEVERLKKMENKKIPEDIDYDAIQGLATEARQKLKQVRPLSIAQA
EEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHH
SRISGVNPADISILLVYLEQGRIARVSNE
HHCCCCCCCCCEEEEEEECCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA