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The map label for this gene is kynB

Identifier: 138896806

GI number: 138896806

Start: 3271416

End: 3272045

Strand: Direct

Name: kynB

Synonym: GTNG_3169

Alternate gene names: 138896806

Gene position: 3271416-3272045 (Clockwise)

Preceding gene: 138896805

Following gene: 138896815

Centisome position: 92.14

GC content: 46.03

Gene sequence:

>630_bases
ATGATGAATCCATGGATCGATATCTCCCAACGACTTGATGAGCATATTCCAGTATGGCCAGGCGATACACCTTTTTCCTA
TCGCACTCGTTGGAACAAGGCGGAAAGTGGATCCGTGAATGTGGGCCAAATCACGATGAGCACACATACAGGCACACACA
TTGATGCTCCCTTTCACTTTGATAACGAAGGAAAGAGAGTCATCGATCTTGATTTAAATATCTATATCGGACCTGCCCGT
GTGATTCATCTTTCGAATCCGAAAAAAATTGGGATCGATGAATTGCAAACGATAGATTTACATGGAGTGACGCGCTTATT
AATCTACACGGGGGCATGGACGAATCGGACAACATTCCCTGAAACTATTCCCTATATTGATCCGCCACTCGCTCCATACT
TGAAAAAATATGGAGTTCGTCTGATCGGGATCGATTTGCCCTCTGTCGACCCGTTAACAAGCAAACAATTGCCTGCCCAT
CACGAATTGCATCGTTGTGGAATTCATATTTTAGAAGGGCTCGTGTTAGACCATGTTTCCCCTGGGGACTATGAACTAGC
GGCTCTTCCTCTCCCCTTAGTCAATGCCGATGGAAGCCCTGTGCGGGCGGCATTACGAAAGATGGGATAA

Upstream 100 bases:

>100_bases
GGGCGTCTCCTACTTAAAAAAATCGCTCGATCGCTCGTTCTTTCCTGAGCTATGGACATTAAGAACAAAACTATAGATTC
AGAGAACTTCAGGAGGCAAA

Downstream 100 bases:

>100_bases
AACCATACAAAAGCATTGGCTTGTTGCTTCGCGTCGGTCGAATACCCATGTCATACAACATGAAAGGTGATGGACCCCAA
AATATGTCTGCCTATCTTCG

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MMNPWIDISQRLDEHIPVWPGDTPFSYRTRWNKAESGSVNVGQITMSTHTGTHIDAPFHFDNEGKRVIDLDLNIYIGPAR
VIHLSNPKKIGIDELQTIDLHGVTRLLIYTGAWTNRTTFPETIPYIDPPLAPYLKKYGVRLIGIDLPSVDPLTSKQLPAH
HELHRCGIHILEGLVLDHVSPGDYELAALPLPLVNADGSPVRAALRKMG

Sequences:

>Translated_209_residues
MMNPWIDISQRLDEHIPVWPGDTPFSYRTRWNKAESGSVNVGQITMSTHTGTHIDAPFHFDNEGKRVIDLDLNIYIGPAR
VIHLSNPKKIGIDELQTIDLHGVTRLLIYTGAWTNRTTFPETIPYIDPPLAPYLKKYGVRLIGIDLPSVDPLTSKQLPAH
HELHRCGIHILEGLVLDHVSPGDYELAALPLPLVNADGSPVRAALRKMG
>Mature_209_residues
MMNPWIDISQRLDEHIPVWPGDTPFSYRTRWNKAESGSVNVGQITMSTHTGTHIDAPFHFDNEGKRVIDLDLNIYIGPAR
VIHLSNPKKIGIDELQTIDLHGVTRLLIYTGAWTNRTTFPETIPYIDPPLAPYLKKYGVRLIGIDLPSVDPLTSKQLPAH
HELHRCGIHILEGLVLDHVSPGDYELAALPLPLVNADGSPVRAALRKMG

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_GEOTN (A4IT60)

Other databases:

- EMBL:   CP000557
- RefSeq:   YP_001127259.1
- ProteinModelPortal:   A4IT60
- SMR:   A4IT60
- STRING:   A4IT60
- GeneID:   4968095
- GenomeReviews:   CP000557_GR
- KEGG:   gtn:GTNG_3169
- NMPDR:   fig|420246.5.peg.3032
- eggNOG:   COG1878
- HOGENOM:   HBG686791
- OMA:   FHFDNDG
- ProtClustDB:   CLSK2787299
- BioCyc:   GTHE420246:GTNG_3169-MONOMER
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 23327; Mature: 23327

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNPWIDISQRLDEHIPVWPGDTPFSYRTRWNKAESGSVNVGQITMSTHTGTHIDAPFHF
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCEEE
DNEGKRVIDLDLNIYIGPARVIHLSNPKKIGIDELQTIDLHGVTRLLIYTGAWTNRTTFP
CCCCCEEEEEEEEEEECCEEEEECCCCCEECCCCEEEECHHHHEEEEEEECCCCCCCCCC
ETIPYIDPPLAPYLKKYGVRLIGIDLPSVDPLTSKQLPAHHELHRCGIHILEGLVLDHVS
CCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PGDYELAALPLPLVNADGSPVRAALRKMG
CCCEEEEEECEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MMNPWIDISQRLDEHIPVWPGDTPFSYRTRWNKAESGSVNVGQITMSTHTGTHIDAPFHF
CCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEECCCEEE
DNEGKRVIDLDLNIYIGPARVIHLSNPKKIGIDELQTIDLHGVTRLLIYTGAWTNRTTFP
CCCCCEEEEEEEEEEECCEEEEECCCCCEECCCCEEEECHHHHEEEEEEECCCCCCCCCC
ETIPYIDPPLAPYLKKYGVRLIGIDLPSVDPLTSKQLPAHHELHRCGIHILEGLVLDHVS
CCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PGDYELAALPLPLVNADGSPVRAALRKMG
CCCEEEEEECEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA