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The map label for this gene is ybgF [H]

Identifier: 138896804

GI number: 138896804

Start: 3269070

End: 3270509

Strand: Direct

Name: ybgF [H]

Synonym: GTNG_3167

Alternate gene names: 138896804

Gene position: 3269070-3270509 (Clockwise)

Preceding gene: 138896803

Following gene: 138896805

Centisome position: 92.08

GC content: 43.4

Gene sequence:

>1440_bases
ATGGCCAAGCAAAATCATGATACGCGTAAATCGCAAGAAAAGGACACCGGATTACATCGTGAATTAAAGACGAACCAACT
AACCATGATCGCTATGGGATGTGCCATTGGCACTGGGCTGTTCCTTGGGAGCGGCCTTGCTATTCAAACGGCGGGACCTA
GCGTTTTACTTAGTTATGCCATTGGCGCTTTCATTGTATTGTTGTTGATGGGGTGTTTGGCTGAAATGACGGTCGCCCAT
CCAACATCAGGTTCCTTTGGAACCATTGCTGACCGGTACATCCACCCCTATGCAGGTTTTATCGTCCGCTATTCGTATTG
GATCGCCAATGTCCTAGCCGTAGGGGTGGAAGTGAGTGCCATTGCCGTTTATATGAGATACTGGTTTCCGCATACACCAG
GGATCCTATGGATTCTACTATTTGGAGGCATTCTCATTTACGTCAATGCTACCAACGTCCATACGTTTGCTACTTTTGAG
TACTGGTTCTCGATGATCAAGGTGAGTGCAGTCATCCTTTTTATTCTCCTTGGAACATATGTTATATTCGGAGCATCAGA
ACAATCTGGAATTGGCCCTGCCAATTTCGTCAATGATGGTGGATTTCTCCCATTTGGCTGGTGGGGCATGTGGGTAGCTA
TTTTTATTTCCCTATTTAGTTTCTTAGGAACAGAAATGATAGCGGTTACATCGGGTGAAGCAAAGGAGCCCGAAATTGCC
GTTCCCAAAGCATTAAAAGCAACGGTTTTTCGTTTGTCTACTTTTTATGTACTCACGCTCGCCATCATGTTGATGATCGT
TCCGTGGAAAGCAGCAGGAATTGACAAAAGTCCTTTTGTGAAAGTAATGGAAATCTTAAACATCCCTAGTGCTTCCGGTG
TGGTAAATTTCATTGTTCTCACTGCGGCGCTATCGGCCATGAATAGTCAGTTATATGCATCAACGAGAATGATGTTCTCA
TTGGCGCAAGAAAAGTATGCTCCCTCTTTCTTTGCTGAGGTGAACAAAAAAGGAGTCCCGATCAAGGCATTACTTATTTC
TACTGCTGGAATTGCCATTTCAGCCATCGTTTCAGCTTTTCTTCCTGATACATCGTATACTGTCATGATGGGGATTTCGA
TGTTTGGGGCAATTTTCACTTGGTTTATGGTTTTTGTTTCCCATCTCTTTTTCCGAAACAAGTGGAATCAAATGAATGGT
CGACCATTGCCCATCAAAATGATTGGATTTCCTTACTTAACCATTTTAGGTGGCGTATTATTACTCAGCTTGATGATTAC
GACATGGTTTACACCATTTAAAACGATGCTGCAATTCGGAATTCCTTGGTTACTGTTGCTATCCATTGCGTATGTCCTTT
GGAAAAGGGTTCATACCACATACCATAACGCAACTCCTTCTACACCATCCGATGAAACAGTCACTAGCGCGAATCAATGA

Upstream 100 bases:

>100_bases
AACGTTGTACAAATTATGAAGAAAATCATGCAAGAGAAACAGTATAAGAAGTTTTCCAACGAGCGTGAAGTAGTCGCCTA
AATATAAGGGGGGAGAGAGA

Downstream 100 bases:

>100_bases
TCGTATCAATCTACCATTCTACGAAAAGGGTGAGAACATATGCAAAATAAACAAAATCAATTCGAACTGGAGAAAGGCAT
TCATACAGATTTCCAAGAAG

Product: amino acid permease

Products: Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MAKQNHDTRKSQEKDTGLHRELKTNQLTMIAMGCAIGTGLFLGSGLAIQTAGPSVLLSYAIGAFIVLLLMGCLAEMTVAH
PTSGSFGTIADRYIHPYAGFIVRYSYWIANVLAVGVEVSAIAVYMRYWFPHTPGILWILLFGGILIYVNATNVHTFATFE
YWFSMIKVSAVILFILLGTYVIFGASEQSGIGPANFVNDGGFLPFGWWGMWVAIFISLFSFLGTEMIAVTSGEAKEPEIA
VPKALKATVFRLSTFYVLTLAIMLMIVPWKAAGIDKSPFVKVMEILNIPSASGVVNFIVLTAALSAMNSQLYASTRMMFS
LAQEKYAPSFFAEVNKKGVPIKALLISTAGIAISAIVSAFLPDTSYTVMMGISMFGAIFTWFMVFVSHLFFRNKWNQMNG
RPLPIKMIGFPYLTILGGVLLLSLMITTWFTPFKTMLQFGIPWLLLLSIAYVLWKRVHTTYHNATPSTPSDETVTSANQ

Sequences:

>Translated_479_residues
MAKQNHDTRKSQEKDTGLHRELKTNQLTMIAMGCAIGTGLFLGSGLAIQTAGPSVLLSYAIGAFIVLLLMGCLAEMTVAH
PTSGSFGTIADRYIHPYAGFIVRYSYWIANVLAVGVEVSAIAVYMRYWFPHTPGILWILLFGGILIYVNATNVHTFATFE
YWFSMIKVSAVILFILLGTYVIFGASEQSGIGPANFVNDGGFLPFGWWGMWVAIFISLFSFLGTEMIAVTSGEAKEPEIA
VPKALKATVFRLSTFYVLTLAIMLMIVPWKAAGIDKSPFVKVMEILNIPSASGVVNFIVLTAALSAMNSQLYASTRMMFS
LAQEKYAPSFFAEVNKKGVPIKALLISTAGIAISAIVSAFLPDTSYTVMMGISMFGAIFTWFMVFVSHLFFRNKWNQMNG
RPLPIKMIGFPYLTILGGVLLLSLMITTWFTPFKTMLQFGIPWLLLLSIAYVLWKRVHTTYHNATPSTPSDETVTSANQ
>Mature_478_residues
AKQNHDTRKSQEKDTGLHRELKTNQLTMIAMGCAIGTGLFLGSGLAIQTAGPSVLLSYAIGAFIVLLLMGCLAEMTVAHP
TSGSFGTIADRYIHPYAGFIVRYSYWIANVLAVGVEVSAIAVYMRYWFPHTPGILWILLFGGILIYVNATNVHTFATFEY
WFSMIKVSAVILFILLGTYVIFGASEQSGIGPANFVNDGGFLPFGWWGMWVAIFISLFSFLGTEMIAVTSGEAKEPEIAV
PKALKATVFRLSTFYVLTLAIMLMIVPWKAAGIDKSPFVKVMEILNIPSASGVVNFIVLTAALSAMNSQLYASTRMMFSL
AQEKYAPSFFAEVNKKGVPIKALLISTAGIAISAIVSAFLPDTSYTVMMGISMFGAIFTWFMVFVSHLFFRNKWNQMNGR
PLPIKMIGFPYLTILGGVLLLSLMITTWFTPFKTMLQFGIPWLLLLSIAYVLWKRVHTTYHNATPSTPSDETVTSANQ

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of Phenylalanine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=364, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI181337167, Length=356, Percent_Identity=24.1573033707865, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI258645169, Length=439, Percent_Identity=23.2346241457859, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786789, Length=423, Percent_Identity=37.5886524822695, Blast_Score=292, Evalue=3e-80,
Organism=Escherichia coli, GI1786302, Length=448, Percent_Identity=34.375, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI87081708, Length=451, Percent_Identity=36.3636363636364, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI1786602, Length=451, Percent_Identity=33.4811529933481, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI48994972, Length=446, Percent_Identity=33.6322869955157, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788480, Length=488, Percent_Identity=34.8360655737705, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1790653, Length=407, Percent_Identity=32.4324324324324, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87081915, Length=425, Percent_Identity=31.0588235294118, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789017, Length=410, Percent_Identity=32.1951219512195, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI2367353, Length=351, Percent_Identity=24.5014245014245, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081869, Length=239, Percent_Identity=25.1046025104602, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532491, Length=365, Percent_Identity=24.3835616438356, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320772, Length=453, Percent_Identity=29.3598233995585, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324061, Length=427, Percent_Identity=29.03981264637, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6324990, Length=406, Percent_Identity=32.0197044334975, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324553, Length=384, Percent_Identity=28.6458333333333, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321629, Length=406, Percent_Identity=28.0788177339901, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322892, Length=396, Percent_Identity=29.7979797979798, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324059, Length=453, Percent_Identity=28.2560706401766, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324924, Length=445, Percent_Identity=29.2134831460674, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6320251, Length=415, Percent_Identity=26.0240963855422, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321053, Length=445, Percent_Identity=25.8426966292135, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319542, Length=414, Percent_Identity=25.3623188405797, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6319824, Length=427, Percent_Identity=24.1217798594848, Blast_Score=146, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=410, Percent_Identity=24.6341463414634, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319543, Length=396, Percent_Identity=25.5050505050505, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319608, Length=530, Percent_Identity=26.2264150943396, Blast_Score=136, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6322967, Length=387, Percent_Identity=27.390180878553, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324981, Length=421, Percent_Identity=30.166270783848, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320364, Length=500, Percent_Identity=23.6, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667468, Length=373, Percent_Identity=23.3243967828418, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221512776, Length=432, Percent_Identity=21.7592592592593, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24666159, Length=432, Percent_Identity=21.7592592592593, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161077963, Length=343, Percent_Identity=25.9475218658892, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52724; Mature: 52593

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQNHDTRKSQEKDTGLHRELKTNQLTMIAMGCAIGTGLFLGSGLAIQTAGPSVLLSYA
CCCCCCCHHHHHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHH
IGAFIVLLLMGCLAEMTVAHPTSGSFGTIADRYIHPYAGFIVRYSYWIANVLAVGVEVSA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IAVYMRYWFPHTPGILWILLFGGILIYVNATNVHTFATFEYWFSMIKVSAVILFILLGTY
HHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
VIFGASEQSGIGPANFVNDGGFLPFGWWGMWVAIFISLFSFLGTEMIAVTSGEAKEPEIA
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
VPKALKATVFRLSTFYVLTLAIMLMIVPWKAAGIDKSPFVKVMEILNIPSASGVVNFIVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
TAALSAMNSQLYASTRMMFSLAQEKYAPSFFAEVNKKGVPIKALLISTAGIAISAIVSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LPDTSYTVMMGISMFGAIFTWFMVFVSHLFFRNKWNQMNGRPLPIKMIGFPYLTILGGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHH
LLSLMITTWFTPFKTMLQFGIPWLLLLSIAYVLWKRVHTTYHNATPSTPSDETVTSANQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKQNHDTRKSQEKDTGLHRELKTNQLTMIAMGCAIGTGLFLGSGLAIQTAGPSVLLSYA
CCCCCCHHHHHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHH
IGAFIVLLLMGCLAEMTVAHPTSGSFGTIADRYIHPYAGFIVRYSYWIANVLAVGVEVSA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
IAVYMRYWFPHTPGILWILLFGGILIYVNATNVHTFATFEYWFSMIKVSAVILFILLGTY
HHHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
VIFGASEQSGIGPANFVNDGGFLPFGWWGMWVAIFISLFSFLGTEMIAVTSGEAKEPEIA
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
VPKALKATVFRLSTFYVLTLAIMLMIVPWKAAGIDKSPFVKVMEILNIPSASGVVNFIVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHH
TAALSAMNSQLYASTRMMFSLAQEKYAPSFFAEVNKKGVPIKALLISTAGIAISAIVSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LPDTSYTVMMGISMFGAIFTWFMVFVSHLFFRNKWNQMNGRPLPIKMIGFPYLTILGGVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHH
LLSLMITTWFTPFKTMLQFGIPWLLLLSIAYVLWKRVHTTYHNATPSTPSDETVTSANQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-phenylalanine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-phenylalanine [Periplasm] = Proton [Cytoplasm] + L-phenylalanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]