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The map label for this gene is ytjP [H]

Identifier: 138896372

GI number: 138896372

Start: 2852485

End: 2853897

Strand: Reverse

Name: ytjP [H]

Synonym: GTNG_2735

Alternate gene names: 138896372

Gene position: 2853897-2852485 (Counterclockwise)

Preceding gene: 138896373

Following gene: 138896371

Centisome position: 80.38

GC content: 57.04

Gene sequence:

>1413_bases
ATGACGTTGAACATCAACTGGATTGAGGAGGCACGGAAACGGAAAGACGATTTAGTTCGCGATGTGCAAGCGCTTGTCCG
CATTCCGAGCGTTCGTGATGACAGCGAGGCGCAGCCAGGAGCGCCGTTTGGACTGAAAGTGGCAGAAGCGCTCGATTATA
TGTTAACCCGCGGTCAAGCGGAAGGGTTTCGCGTCAAAAACGTCGACGGGTTTGCCGGACATGTGGAAATGGGGCAAGGG
GAGAAGCTTATCGGTGTGCTCGGCCATATCGACGTCGTGCCGCCCGGGGATGGCTGGACGGTTGATCCGTTCTCCGCTCA
TGTGAGGGACGGCCGCATTTACGGGCGTGGGGCCATCGATGACAAAGGGCCGACCATCGCTGCGTTTTACGCAATGAAAA
TCGTGAAAGAACTCGGCCTGCCGCTGAGCAAGCGGGTTCGTCTCATCATCGGAGGGGATGAGGAAAGCGATTGGCGGTGT
GTCGACCATTATTTCAAGCATGAAGAGATGCCGGACATTGGGTTTGTCCCGGACGCTGATTTTCCGATTATTTATGCGGA
AAAAGGGATTATTGACGCTGATTTGCAATATCGGCTGACGGGGAGCGAAGAAACGGGAGAAATGACGCTTCGCTCGTTTC
AAGCAGGCCGCCGCTACAATATGGTGCCTGATGCGGCCGAAGCCGTTGTCGAAGGAGCCGGGCTGGAGGAATGGTCTAGC
CGGTATGAGCGCTTTTGCCGTGACCACGGATTAAACGGGAACATCCACCATAGCGGCGAAGCGGCTGTGCTTACGCTGGA
AGGAGTGGCTGCTCATGGCGCCGAACCGGAGCGCGGCAAAAATGCCGGCGTCTACTTGGCGCAATTTTTAGCGAGCCTTC
CGCTAGATGGCGGTAGCCGGCCGTTTGTCCAGTTTGTGGCGTCCTCGTTTTTCGGCGACACGCGCGGACGGAAGCTCGGT
CTGGCGTATCGGGATGAGCGGAGCGGTGAGCTGACCGTGAATGTCGGCGTGTTGTCATACGACCGTGCGCAGGGCGGGAC
CATCGGGTTGAACATTCGCTATCCGGTGACGGCCGACGGGGAAACGATCCGTCAAACGTTGTCCAACGTGGCTGTTGAAC
GCGGCCTGACGCTCGGGCGTTTCCATGATACGAAACCGCATTACGTCGATCCGGATCATGAGTGGATCCGCACGCTTCAA
CGCATCTATGAAGAACAAACCGGTGAGCCTGGTCGGCTGTTGGCGATTGGCGGCGGCACGTATGCCCGCTCGTTGACCGC
CGGGGTGGCGTTCGGTGCTTTGTTTCCTGGCCGCCCTGATGTCGCCCATCAAAAAGATGAATATGTCGAGATTGACGATT
TAGTGAAAGCGACTGCCATTTACGCTCAGGCGATCTATGAGCTGGCCAAATAA

Upstream 100 bases:

>100_bases
TGTAGCAAAAATGAAACGAAGTTGTGACAAATGAAAAATTTTGACAACCTTTTTTTGATATGATACGTTGGCAACAAAGA
GTGATAAAAAGAAAGGGAGA

Downstream 100 bases:

>100_bases
ACCGCTGCTTCGGAACGGCTTAAGAAATAGAATGGTTGCCCCACAAGACAGCAATGTTGTGACAAGGAAAGGGGAGAACG
GGATGGAAGCAGCCTTAAAA

Product: Xaa-His dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTLNINWIEEARKRKDDLVRDVQALVRIPSVRDDSEAQPGAPFGLKVAEALDYMLTRGQAEGFRVKNVDGFAGHVEMGQG
EKLIGVLGHIDVVPPGDGWTVDPFSAHVRDGRIYGRGAIDDKGPTIAAFYAMKIVKELGLPLSKRVRLIIGGDEESDWRC
VDHYFKHEEMPDIGFVPDADFPIIYAEKGIIDADLQYRLTGSEETGEMTLRSFQAGRRYNMVPDAAEAVVEGAGLEEWSS
RYERFCRDHGLNGNIHHSGEAAVLTLEGVAAHGAEPERGKNAGVYLAQFLASLPLDGGSRPFVQFVASSFFGDTRGRKLG
LAYRDERSGELTVNVGVLSYDRAQGGTIGLNIRYPVTADGETIRQTLSNVAVERGLTLGRFHDTKPHYVDPDHEWIRTLQ
RIYEEQTGEPGRLLAIGGGTYARSLTAGVAFGALFPGRPDVAHQKDEYVEIDDLVKATAIYAQAIYELAK

Sequences:

>Translated_470_residues
MTLNINWIEEARKRKDDLVRDVQALVRIPSVRDDSEAQPGAPFGLKVAEALDYMLTRGQAEGFRVKNVDGFAGHVEMGQG
EKLIGVLGHIDVVPPGDGWTVDPFSAHVRDGRIYGRGAIDDKGPTIAAFYAMKIVKELGLPLSKRVRLIIGGDEESDWRC
VDHYFKHEEMPDIGFVPDADFPIIYAEKGIIDADLQYRLTGSEETGEMTLRSFQAGRRYNMVPDAAEAVVEGAGLEEWSS
RYERFCRDHGLNGNIHHSGEAAVLTLEGVAAHGAEPERGKNAGVYLAQFLASLPLDGGSRPFVQFVASSFFGDTRGRKLG
LAYRDERSGELTVNVGVLSYDRAQGGTIGLNIRYPVTADGETIRQTLSNVAVERGLTLGRFHDTKPHYVDPDHEWIRTLQ
RIYEEQTGEPGRLLAIGGGTYARSLTAGVAFGALFPGRPDVAHQKDEYVEIDDLVKATAIYAQAIYELAK
>Mature_469_residues
TLNINWIEEARKRKDDLVRDVQALVRIPSVRDDSEAQPGAPFGLKVAEALDYMLTRGQAEGFRVKNVDGFAGHVEMGQGE
KLIGVLGHIDVVPPGDGWTVDPFSAHVRDGRIYGRGAIDDKGPTIAAFYAMKIVKELGLPLSKRVRLIIGGDEESDWRCV
DHYFKHEEMPDIGFVPDADFPIIYAEKGIIDADLQYRLTGSEETGEMTLRSFQAGRRYNMVPDAAEAVVEGAGLEEWSSR
YERFCRDHGLNGNIHHSGEAAVLTLEGVAAHGAEPERGKNAGVYLAQFLASLPLDGGSRPFVQFVASSFFGDTRGRKLGL
AYRDERSGELTVNVGVLSYDRAQGGTIGLNIRYPVTADGETIRQTLSNVAVERGLTLGRFHDTKPHYVDPDHEWIRTLQR
IYEEQTGEPGRLLAIGGGTYARSLTAGVAFGALFPGRPDVAHQKDEYVEIDDLVKATAIYAQAIYELAK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17563146, Length=100, Percent_Identity=35, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211059, Length=80, Percent_Identity=37.5, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585880, Length=106, Percent_Identity=34.9056603773585, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 51677; Mature: 51546

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNINWIEEARKRKDDLVRDVQALVRIPSVRDDSEAQPGAPFGLKVAEALDYMLTRGQA
CEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
EGFRVKNVDGFAGHVEMGQGEKLIGVLGHIDVVPPGDGWTVDPFSAHVRDGRIYGRGAID
CCEEEECCCCCCCEEECCCCCEEEEEECCEEEECCCCCCEECCCHHHCCCCEEEECCCCC
DKGPTIAAFYAMKIVKELGLPLSKRVRLIIGGDEESDWRCVDHYFKHEEMPDIGFVPDAD
CCCCCHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
FPIIYAEKGIIDADLQYRLTGSEETGEMTLRSFQAGRRYNMVPDAAEAVVEGAGLEEWSS
CCEEEECCCEEECCCEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHH
RYERFCRDHGLNGNIHHSGEAAVLTLEGVAAHGAEPERGKNAGVYLAQFLASLPLDGGSR
HHHHHHHHCCCCCCEECCCCEEEEEEECHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
PFVQFVASSFFGDTRGRKLGLAYRDERSGELTVNVGVLSYDRAQGGTIGLNIRYPVTADG
HHHHHHHHHHCCCCCCCEECEEEECCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCCH
ETIRQTLSNVAVERGLTLGRFHDTKPHYVDPDHEWIRTLQRIYEEQTGEPGRLLAIGGGT
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCH
YARSLTAGVAFGALFPGRPDVAHQKDEYVEIDDLVKATAIYAQAIYELAK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TLNINWIEEARKRKDDLVRDVQALVRIPSVRDDSEAQPGAPFGLKVAEALDYMLTRGQA
EEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
EGFRVKNVDGFAGHVEMGQGEKLIGVLGHIDVVPPGDGWTVDPFSAHVRDGRIYGRGAID
CCEEEECCCCCCCEEECCCCCEEEEEECCEEEECCCCCCEECCCHHHCCCCEEEECCCCC
DKGPTIAAFYAMKIVKELGLPLSKRVRLIIGGDEESDWRCVDHYFKHEEMPDIGFVPDAD
CCCCCHHHHHHHHHHHHHCCCHHHCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
FPIIYAEKGIIDADLQYRLTGSEETGEMTLRSFQAGRRYNMVPDAAEAVVEGAGLEEWSS
CCEEEECCCEEECCCEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHH
RYERFCRDHGLNGNIHHSGEAAVLTLEGVAAHGAEPERGKNAGVYLAQFLASLPLDGGSR
HHHHHHHHCCCCCCEECCCCEEEEEEECHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
PFVQFVASSFFGDTRGRKLGLAYRDERSGELTVNVGVLSYDRAQGGTIGLNIRYPVTADG
HHHHHHHHHHCCCCCCCEECEEEECCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCCH
ETIRQTLSNVAVERGLTLGRFHDTKPHYVDPDHEWIRTLQRIYEEQTGEPGRLLAIGGGT
HHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCH
YARSLTAGVAFGALFPGRPDVAHQKDEYVEIDDLVKATAIYAQAIYELAK
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]