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The map label for this gene is murC [H]

Identifier: 138896357

GI number: 138896357

Start: 2835736

End: 2837040

Strand: Reverse

Name: murC [H]

Synonym: GTNG_2720

Alternate gene names: 138896357

Gene position: 2837040-2835736 (Counterclockwise)

Preceding gene: 138896358

Following gene: 138896356

Centisome position: 79.91

GC content: 50.11

Gene sequence:

>1305_bases
ATGACAGTTTACCATTTTGTTGGCATTAAAGGCACGGGGATGAGCGCGCTCGCGCAAGTGCTTTATGATCTCGGCTATAC
AGTGCAAGGATCGGACGTAGAAAAATGGTTTTTTACACAAAAGGCACTTGAAGAGCGGGGAATCCCGGTTTTGCCTTTTT
CAAAAGATAATGTTCACCCGGGTTATACGGTCATTGCCGGCAATGCATTTCCGGACACGCACGAGGAAATCGAAGCCGCT
CGTCAGCTCAGTGTTCCTGTCATTCGGTACCATCGCTTTTTAGGTGAGTTGGCAAGCAAGTTTACGAGTATAGCGGTGAC
CGGCTCGCACGGAAAGACGACGACGACGGGGCTGCTCGCTCATGTGATGCAAGGGGCGCATCCAACGTCGTATTTAATCG
GAGATGGAACGGGAAAAGGGGAGCCGGGGAGCAAATACTTTGTATTTGAAGCGTGTGAATACCGAAGACACTTTCTCTCC
TATTTTCCAGATTATGCAATTATCACGAACATTGACTTCGACCACCCAGATTATTTTGCCAATATCGACGACGTCTTTTC
TGCTTTCCAGCAGATGGCGCAACAAGTGAAAAAAGGGATTGTCGCTTGTGGGGACGATCCGTATTTGCAAAATATTCAAG
CCAAAGTGCCGATCTTGTTTTATGGGCTTGGCGAAGAAAATGATTTTCAGGCGCGCAACATCGTGAAAACGACAGAAGGA
ACGGCGTTTGACGTATTTGTGCGCAACACGTTTTTCGCCTCGTTTACCATTCCGCGCTTCGGCACTCATAACGTGCTGAA
TGCGCTCGCGGTCATCGCCCTTTGTCATTACGAGGGAATTGACGCTGGCACGATCGCTGCGCGGCTGCAAACGTTCCAAG
GAGTGAAGCGCCGCTTTACCGAAAAAACGGTCGGGCGCCAAGTGTTAATTGACGATTATGCGCATCATCCGCGCGAAATT
ATGGCGACATTGGAAGCAGCTAGACAAAAATACCCGGGGCGCGAAGTCGTCGCTATTTTTCAGCCGCACACGTATACGCG
GACGCAAACATTTTTGAGTGAGTTTGCCGAAAGCTTGCAGCAGGCCGACTATGTTTATTTGTGCGACATTTTCGGCTCGG
CGCGCGAACATCATGGCAAGCTGTCTATTCGGGACTTACAGGAGAAAATCCCGCGCTCGCAGCTGCTTGAGGAGCAAAAC
GTGTCGGTGTTGAAGCAGCATCGCGATGCAGTGCTTGTGTTTATGGGTGCCGGCGACATTCAAAAGTTTCAACATGCATA
CGAACAGGCCGTTCTCTCCGCCTGA

Upstream 100 bases:

>100_bases
GGGAAATGAGACAGTTGGTACAGTAGGATGAAATAAATGGCAAAAATAGATAAATATCATATACTGTCTTACAGAGAGAC
GATGGTTGGAGGGCTTAGCG

Downstream 100 bases:

>100_bases
CGGCCGACAGGAAGCAGGCCGTGATCAAGACGGCCTGTTTTTTATGGGAAGACGTTTACTCGTAAACGAAGCAAACGGAA
TGAGAAATGCGGTTCGTCTT

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTVYHFVGIKGTGMSALAQVLYDLGYTVQGSDVEKWFFTQKALEERGIPVLPFSKDNVHPGYTVIAGNAFPDTHEEIEAA
RQLSVPVIRYHRFLGELASKFTSIAVTGSHGKTTTTGLLAHVMQGAHPTSYLIGDGTGKGEPGSKYFVFEACEYRRHFLS
YFPDYAIITNIDFDHPDYFANIDDVFSAFQQMAQQVKKGIVACGDDPYLQNIQAKVPILFYGLGEENDFQARNIVKTTEG
TAFDVFVRNTFFASFTIPRFGTHNVLNALAVIALCHYEGIDAGTIAARLQTFQGVKRRFTEKTVGRQVLIDDYAHHPREI
MATLEAARQKYPGREVVAIFQPHTYTRTQTFLSEFAESLQQADYVYLCDIFGSAREHHGKLSIRDLQEKIPRSQLLEEQN
VSVLKQHRDAVLVFMGAGDIQKFQHAYEQAVLSA

Sequences:

>Translated_434_residues
MTVYHFVGIKGTGMSALAQVLYDLGYTVQGSDVEKWFFTQKALEERGIPVLPFSKDNVHPGYTVIAGNAFPDTHEEIEAA
RQLSVPVIRYHRFLGELASKFTSIAVTGSHGKTTTTGLLAHVMQGAHPTSYLIGDGTGKGEPGSKYFVFEACEYRRHFLS
YFPDYAIITNIDFDHPDYFANIDDVFSAFQQMAQQVKKGIVACGDDPYLQNIQAKVPILFYGLGEENDFQARNIVKTTEG
TAFDVFVRNTFFASFTIPRFGTHNVLNALAVIALCHYEGIDAGTIAARLQTFQGVKRRFTEKTVGRQVLIDDYAHHPREI
MATLEAARQKYPGREVVAIFQPHTYTRTQTFLSEFAESLQQADYVYLCDIFGSAREHHGKLSIRDLQEKIPRSQLLEEQN
VSVLKQHRDAVLVFMGAGDIQKFQHAYEQAVLSA
>Mature_433_residues
TVYHFVGIKGTGMSALAQVLYDLGYTVQGSDVEKWFFTQKALEERGIPVLPFSKDNVHPGYTVIAGNAFPDTHEEIEAAR
QLSVPVIRYHRFLGELASKFTSIAVTGSHGKTTTTGLLAHVMQGAHPTSYLIGDGTGKGEPGSKYFVFEACEYRRHFLSY
FPDYAIITNIDFDHPDYFANIDDVFSAFQQMAQQVKKGIVACGDDPYLQNIQAKVPILFYGLGEENDFQARNIVKTTEGT
AFDVFVRNTFFASFTIPRFGTHNVLNALAVIALCHYEGIDAGTIAARLQTFQGVKRRFTEKTVGRQVLIDDYAHHPREIM
ATLEAARQKYPGREVVAIFQPHTYTRTQTFLSEFAESLQQADYVYLCDIFGSAREHHGKLSIRDLQEKIPRSQLLEEQNV
SVLKQHRDAVLVFMGAGDIQKFQHAYEQAVLSA

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=389, Percent_Identity=31.8766066838046, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790680, Length=386, Percent_Identity=29.5336787564767, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 48693; Mature: 48561

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYHFVGIKGTGMSALAQVLYDLGYTVQGSDVEKWFFTQKALEERGIPVLPFSKDNVHP
CEEEEEEEECCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCC
GYTVIAGNAFPDTHEEIEAARQLSVPVIRYHRFLGELASKFTSIAVTGSHGKTTTTGLLA
CEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHH
HVMQGAHPTSYLIGDGTGKGEPGSKYFVFEACEYRRHFLSYFPDYAIITNIDFDHPDYFA
HHHHCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCHHHC
NIDDVFSAFQQMAQQVKKGIVACGDDPYLQNIQAKVPILFYGLGEENDFQARNIVKTTEG
CHHHHHHHHHHHHHHHHCCEEECCCCHHHHCCCCCCCEEEEECCCCCCCCHHCEEECCCC
TAFDVFVRNTFFASFTIPRFGTHNVLNALAVIALCHYEGIDAGTIAARLQTFQGVKRRFT
CEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EKTVGRQVLIDDYAHHPREIMATLEAARQKYPGREVVAIFQPHTYTRTQTFLSEFAESLQ
HHHHCCEEEEHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
QADYVYLCDIFGSAREHHGKLSIRDLQEKIPRSQLLEEQNVSVLKQHRDAVLVFMGAGDI
HCCEEEEEEHHHCHHHHCCCCCHHHHHHHCCHHHHHHHCCHHHHHHCCCEEEEEECCCHH
QKFQHAYEQAVLSA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
TVYHFVGIKGTGMSALAQVLYDLGYTVQGSDVEKWFFTQKALEERGIPVLPFSKDNVHP
EEEEEEEECCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCEEECCCCCCCCC
GYTVIAGNAFPDTHEEIEAARQLSVPVIRYHRFLGELASKFTSIAVTGSHGKTTTTGLLA
CEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHH
HVMQGAHPTSYLIGDGTGKGEPGSKYFVFEACEYRRHFLSYFPDYAIITNIDFDHPDYFA
HHHHCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCHHHC
NIDDVFSAFQQMAQQVKKGIVACGDDPYLQNIQAKVPILFYGLGEENDFQARNIVKTTEG
CHHHHHHHHHHHHHHHHCCEEECCCCHHHHCCCCCCCEEEEECCCCCCCCHHCEEECCCC
TAFDVFVRNTFFASFTIPRFGTHNVLNALAVIALCHYEGIDAGTIAARLQTFQGVKRRFT
CEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EKTVGRQVLIDDYAHHPREIMATLEAARQKYPGREVVAIFQPHTYTRTQTFLSEFAESLQ
HHHHCCEEEEHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
QADYVYLCDIFGSAREHHGKLSIRDLQEKIPRSQLLEEQNVSVLKQHRDAVLVFMGAGDI
HCCEEEEEEHHHCHHHHCCCCCHHHHHHHCCHHHHHHHCCHHHHHHCCCEEEEEECCCHH
QKFQHAYEQAVLSA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA