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The map label for this gene is nrnA [H]

Identifier: 138896308

GI number: 138896308

Start: 2781825

End: 2782772

Strand: Reverse

Name: nrnA [H]

Synonym: GTNG_2671

Alternate gene names: 138896308

Gene position: 2782772-2781825 (Counterclockwise)

Preceding gene: 138896310

Following gene: 138896305

Centisome position: 78.38

GC content: 54.43

Gene sequence:

>948_bases
ATGAGAGAACAATGCCGACAAATTTTAGATGCGATTCGCCAATTTGACACGATCATCATTCACCGCCATGTGCGTCCAGA
TCCGGATGCGTACGGGTCGCAAGGTGGATTGGCGGCGCTGCTTCAAGCGTCATTTCCGGAAAAACGGGTGTATGCAGTCG
GGACAGATGATCCGTCGTTGTCATTTTTGCGGAAAATGGATGTCATTGACGACGATGTGTATGAACAGGCGCTTGTGATC
GTCTGCGATACGGCCAATGAGGAGCGGATTTGTGACGGCCGCTACCGGCTTGGACGGAAACTCATCAAAATCGACCACCA
CCCGAACGACACGCCGTACGGTGATATGATGTGGGTCGATACCACAGCCAGCTCGACAAGCGAAATGATTTACGAGTTCT
ATTTGGCGGGGAAAGATCACGGGCTGACGATGACGGTGGAGGCGGCACGCTTAATCTACGCCGGTATTGTCGGGGATACG
GGCCGCTTTTTGTTTCCGCGCACGAGTGAAAAAACGTTCCGTTACGCCGGGGAGCTCATTTCGTACGGCTTTTCGCTCTC
AGAGTTGTATGACGGGCTGTATCGAACAAGCTTGCCGCTCGCGCGTTTGAGCGGTTACGTGCTGTCGAATTTCACGATCG
ACGAAGGAGTGGCGGCGGTGAAAATGCCGCGGGCGCTTCTTGAGGAGTACGGCGTTGCTCCGCTTGAAGCGTCGCAGCTT
GTCGGATTGCTCGGCAATATCGATGGCATTGTTGCCTGGGTGTTTTTCATTGAGGAAGAGAAGGAGATTCGCGTCCGCTT
CCGGTCAAAAGGACCGATCATCAATGTTGTCGCCAAACAGTACGGCGGCGGAGGCCATCCGCTTGCGGCCGGTGCTTCCA
TCGCTTCATGGGAAGAAGCTGACCGTATTGTTGAAGATGTGAAAGCCGTCTGTCGGGCCGAGCGGTAA

Upstream 100 bases:

>100_bases
AGATGATCCCTCCGTTGTCCATTTCTTTTCCCATTGTACATAGAAACGGAAAAAAAGGCCAGCGGTTGAAAATGACAGGT
AATCCAAAAGGGGAAGAACG

Downstream 100 bases:

>100_bases
AGGAAGGAGTTGTTCTTCCGGAAAAAGCCCATATGCGCCGATATGGTCATGAGAAAAGGTGTCCCGACCTTTGGGGACAC
CCTCTTTTGCCGCCGGCGGA

Product: phosphoesterase, DHH family protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MREQCRQILDAIRQFDTIIIHRHVRPDPDAYGSQGGLAALLQASFPEKRVYAVGTDDPSLSFLRKMDVIDDDVYEQALVI
VCDTANEERICDGRYRLGRKLIKIDHHPNDTPYGDMMWVDTTASSTSEMIYEFYLAGKDHGLTMTVEAARLIYAGIVGDT
GRFLFPRTSEKTFRYAGELISYGFSLSELYDGLYRTSLPLARLSGYVLSNFTIDEGVAAVKMPRALLEEYGVAPLEASQL
VGLLGNIDGIVAWVFFIEEEKEIRVRFRSKGPIINVVAKQYGGGGHPLAAGASIASWEEADRIVEDVKAVCRAER

Sequences:

>Translated_315_residues
MREQCRQILDAIRQFDTIIIHRHVRPDPDAYGSQGGLAALLQASFPEKRVYAVGTDDPSLSFLRKMDVIDDDVYEQALVI
VCDTANEERICDGRYRLGRKLIKIDHHPNDTPYGDMMWVDTTASSTSEMIYEFYLAGKDHGLTMTVEAARLIYAGIVGDT
GRFLFPRTSEKTFRYAGELISYGFSLSELYDGLYRTSLPLARLSGYVLSNFTIDEGVAAVKMPRALLEEYGVAPLEASQL
VGLLGNIDGIVAWVFFIEEEKEIRVRFRSKGPIINVVAKQYGGGGHPLAAGASIASWEEADRIVEDVKAVCRAER
>Mature_315_residues
MREQCRQILDAIRQFDTIIIHRHVRPDPDAYGSQGGLAALLQASFPEKRVYAVGTDDPSLSFLRKMDVIDDDVYEQALVI
VCDTANEERICDGRYRLGRKLIKIDHHPNDTPYGDMMWVDTTASSTSEMIYEFYLAGKDHGLTMTVEAARLIYAGIVGDT
GRFLFPRTSEKTFRYAGELISYGFSLSELYDGLYRTSLPLARLSGYVLSNFTIDEGVAAVKMPRALLEEYGVAPLEASQL
VGLLGNIDGIVAWVFFIEEEKEIRVRFRSKGPIINVVAKQYGGGGHPLAAGASIASWEEADRIVEDVKAVCRAER

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 35116; Mature: 35116

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREQCRQILDAIRQFDTIIIHRHVRPDPDAYGSQGGLAALLQASFPEKRVYAVGTDDPSL
CCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCHH
SFLRKMDVIDDDVYEQALVIVCDTANEERICDGRYRLGRKLIKIDHHPNDTPYGDMMWVD
HHHHHHHCCCHHHHCCEEEEEEECCCCCCCCCCHHHHCCEEEEECCCCCCCCCCCEEEEE
TTASSTSEMIYEFYLAGKDHGLTMTVEAARLIYAGIVGDTGRFLFPRTSEKTFRYAGELI
CCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHEECCCCCEECCCCCCHHHHHHHHHH
SYGFSLSELYDGLYRTSLPLARLSGYVLSNFTIDEGVAAVKMPRALLEEYGVAPLEASQL
HHCCCHHHHHHHHHHHCCCHHHHCCHHHCCCCHHCCHHHHHHHHHHHHHCCCCCCCHHHH
VGLLGNIDGIVAWVFFIEEEKEIRVRFRSKGPIINVVAKQYGGGGHPLAAGASIASWEEA
HHHHHCHHHHEEEEHEEECCCEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCHHHHHHH
DRIVEDVKAVCRAER
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MREQCRQILDAIRQFDTIIIHRHVRPDPDAYGSQGGLAALLQASFPEKRVYAVGTDDPSL
CCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCHH
SFLRKMDVIDDDVYEQALVIVCDTANEERICDGRYRLGRKLIKIDHHPNDTPYGDMMWVD
HHHHHHHCCCHHHHCCEEEEEEECCCCCCCCCCHHHHCCEEEEECCCCCCCCCCCEEEEE
TTASSTSEMIYEFYLAGKDHGLTMTVEAARLIYAGIVGDTGRFLFPRTSEKTFRYAGELI
CCCCHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHEECCCCCEECCCCCCHHHHHHHHHH
SYGFSLSELYDGLYRTSLPLARLSGYVLSNFTIDEGVAAVKMPRALLEEYGVAPLEASQL
HHCCCHHHHHHHHHHHCCCHHHHCCHHHCCCCHHCCHHHHHHHHHHHHHCCCCCCCHHHH
VGLLGNIDGIVAWVFFIEEEKEIRVRFRSKGPIINVVAKQYGGGGHPLAAGASIASWEEA
HHHHHCHHHHEEEEHEEECCCEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCHHHHHHH
DRIVEDVKAVCRAER
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]