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The map label for this gene is nrdR [H]

Identifier: 138896284

GI number: 138896284

Start: 2755811

End: 2756308

Strand: Reverse

Name: nrdR [H]

Synonym: GTNG_2647

Alternate gene names: 138896284

Gene position: 2756308-2755811 (Counterclockwise)

Preceding gene: 138896285

Following gene: 138896283

Centisome position: 77.64

GC content: 48.19

Gene sequence:

>498_bases
ATGATAGAAAATAAGAAGACAAACGGAGTGAATGTTATGCGGTGTCCGTCATGCCATCATCAAGGCACGCGCGTGCTTGA
TTCGCGTCCAGCCGAGGAAGGCCGTTCGATCCGTCGTCGGCGGGAGTGTGAACGGTGCCATTATCGGTTTACGACGTTTG
AGCGGATCGAGGAGCCGCCGCTCATTGTCGTGAAAAAAGAAGGGACGCGCGAAGAATTCAGCCGAGAAAAAATTTTGCGT
GGCTTGATTAAAGCGTGTGAAAAACGGCCGGTGGCGTTGGAAGAACTGGAAAAAGTGACGCAAGAAATCGAGCGAGAGTT
GCGTAATCAAGGCGTATCGGAAGTGAAAAGCGAAACGATCGGTGAAATGGTCATGGAGCGGCTGTCGCGCATCGATGAAG
TGGCTTATGTCCGTTTTGCTTCCGTCTATCGCCAGTTTAAAGATATTAATGTATTTATTGAAGAACTAAAAGAGTTGATT
AAAAAAGGACAGCGGTAA

Upstream 100 bases:

>100_bases
GTGATCCTCGAATTGTACCGGAAGCTTGATGCCCGTCTGCCGTATATCGGCTCCGGGTTAAACGGCTAACTATGGCTTGT
CTGCTTTTCTCCATTCCGGT

Downstream 100 bases:

>100_bases
AAGGGCTTTCGCGTTAGGCAGCAAGCCCTTTTTTCAACGTTTTTTCGGGCAGGAAAGGAGAGAGGCGGGTTGAAACGAAT
ACGACGAAATGGAAGGTTGG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MIENKKTNGVNVMRCPSCHHQGTRVLDSRPAEEGRSIRRRRECERCHYRFTTFERIEEPPLIVVKKEGTREEFSREKILR
GLIKACEKRPVALEELEKVTQEIERELRNQGVSEVKSETIGEMVMERLSRIDEVAYVRFASVYRQFKDINVFIEELKELI
KKGQR

Sequences:

>Translated_165_residues
MIENKKTNGVNVMRCPSCHHQGTRVLDSRPAEEGRSIRRRRECERCHYRFTTFERIEEPPLIVVKKEGTREEFSREKILR
GLIKACEKRPVALEELEKVTQEIERELRNQGVSEVKSETIGEMVMERLSRIDEVAYVRFASVYRQFKDINVFIEELKELI
KKGQR
>Mature_165_residues
MIENKKTNGVNVMRCPSCHHQGTRVLDSRPAEEGRSIRRRRECERCHYRFTTFERIEEPPLIVVKKEGTREEFSREKILR
GLIKACEKRPVALEELEKVTQEIERELRNQGVSEVKSETIGEMVMERLSRIDEVAYVRFASVYRQFKDINVFIEELKELI
KKGQR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=48.9795918367347, Blast_Score=137, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 19567; Mature: 19567

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIENKKTNGVNVMRCPSCHHQGTRVLDSRPAEEGRSIRRRRECERCHYRFTTFERIEEPP
CCCCCCCCCCCEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LIVVKKEGTREEFSREKILRGLIKACEKRPVALEELEKVTQEIERELRNQGVSEVKSETI
EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GEMVMERLSRIDEVAYVRFASVYRQFKDINVFIEELKELIKKGQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIENKKTNGVNVMRCPSCHHQGTRVLDSRPAEEGRSIRRRRECERCHYRFTTFERIEEPP
CCCCCCCCCCCEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LIVVKKEGTREEFSREKILRGLIKACEKRPVALEELEKVTQEIERELRNQGVSEVKSETI
EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
GEMVMERLSRIDEVAYVRFASVYRQFKDINVFIEELKELIKKGQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA