Click here to switch to the map view.

The map label for this gene is sdhB [H]

Identifier: 138896236

GI number: 138896236

Start: 2707353

End: 2708114

Strand: Reverse

Name: sdhB [H]

Synonym: GTNG_2599

Alternate gene names: 138896236

Gene position: 2708114-2707353 (Counterclockwise)

Preceding gene: 138896237

Following gene: 138896235

Centisome position: 76.28

GC content: 55.12

Gene sequence:

>762_bases
ATGAGCGAGAACAAAACGGTTCGATTCATCATTACGCGCCAAGATCGTCCGGACTCTGCACCATATGAAGAAGAGTTTGT
CATCCCGTACCGTCCGAACATGAACGTCATTTCGGCGCTCATGGAAATTCGCCGCAATCCGGTTAACGCCAAAGGGGAAA
AAACAACACCAGTCGTTTGGGAAATGAACTGTTTGGAAGAAGTGTGCGGAGCATGTTCGATGGTGATTAACGGCAAGCCG
CGCCAAGCGTGTGCGGCCTTGATCGACCAGCTTGAGCAGCCGATCCGCCTCGAGCCGATGCGCACGTTCCCAGTCATCCG
TGACTTGGCGATCGACCGTAGCCGGATGTTTGACGCCTTAAAGAGAGTAAAAGCGTGGATCCCGATCGACGGGACGTATG
ACTTAGGTCCTGGCCCGCGCATGCCGGAGCGGAAACGGCAGTGGGCATACGAGTTGTCAAAATGCATGACGTGCGGCGTG
TGCCTTGAGGCGTGTCCGAATGTCAACAGCAAGTCGAACTTTATCGGCCCGGCGCCGCTGTCGCAAGTGCGGCTGTTCAA
CGCCCATCCGACCGGAGCGATGCATAAAGCGGAACGGCTGCGGACTATTATGGGCGACGGCGGCTTGGCGAACTGCGGCA
ACTCACAAAACTGTGTGCAATCATGCCCGAAAGGCATTCCGCTGACAACATCGATCGCCGCTTTAAACCGTGATACGACG
ATTCAAATGTTCCGCGATTTCTTCGGCAGCGACGAAGTATAA

Upstream 100 bases:

>100_bases
ACGCCAGACGGTCCGTCGTTCCATTACGAAGACGTCGATGTTTCGTTGATTAAGCCGCGCAAACGCGACTACAGCAAAAA
GAAAGAGGAAGTGAAGTAAG

Downstream 100 bases:

>100_bases
TGAGGACGATATCCATCCCCTTCATGGTCAGCCATGAAGGGGATTTCTTGTCCTAGGTGCCGGATGGATACCGCCTGTCG
GGCGGATGCAGCCTGCTGAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSENKTVRFIITRQDRPDSAPYEEEFVIPYRPNMNVISALMEIRRNPVNAKGEKTTPVVWEMNCLEEVCGACSMVINGKP
RQACAALIDQLEQPIRLEPMRTFPVIRDLAIDRSRMFDALKRVKAWIPIDGTYDLGPGPRMPERKRQWAYELSKCMTCGV
CLEACPNVNSKSNFIGPAPLSQVRLFNAHPTGAMHKAERLRTIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTT
IQMFRDFFGSDEV

Sequences:

>Translated_253_residues
MSENKTVRFIITRQDRPDSAPYEEEFVIPYRPNMNVISALMEIRRNPVNAKGEKTTPVVWEMNCLEEVCGACSMVINGKP
RQACAALIDQLEQPIRLEPMRTFPVIRDLAIDRSRMFDALKRVKAWIPIDGTYDLGPGPRMPERKRQWAYELSKCMTCGV
CLEACPNVNSKSNFIGPAPLSQVRLFNAHPTGAMHKAERLRTIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTT
IQMFRDFFGSDEV
>Mature_252_residues
SENKTVRFIITRQDRPDSAPYEEEFVIPYRPNMNVISALMEIRRNPVNAKGEKTTPVVWEMNCLEEVCGACSMVINGKPR
QACAALIDQLEQPIRLEPMRTFPVIRDLAIDRSRMFDALKRVKAWIPIDGTYDLGPGPRMPERKRQWAYELSKCMTCGVC
LEACPNVNSKSNFIGPAPLSQVRLFNAHPTGAMHKAERLRTIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTTI
QMFRDFFGSDEV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=238, Percent_Identity=26.4705882352941, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1790596, Length=250, Percent_Identity=24.8, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786943, Length=228, Percent_Identity=28.0701754385965, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17533915, Length=196, Percent_Identity=25, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322987, Length=247, Percent_Identity=25.5060728744939, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643156, Length=227, Percent_Identity=26.8722466960352, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17137106, Length=244, Percent_Identity=25, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28355; Mature: 28224

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENKTVRFIITRQDRPDSAPYEEEFVIPYRPNMNVISALMEIRRNPVNAKGEKTTPVVW
CCCCCEEEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
EMNCLEEVCGACSMVINGKPRQACAALIDQLEQPIRLEPMRTFPVIRDLAIDRSRMFDAL
EHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KRVKAWIPIDGTYDLGPGPRMPERKRQWAYELSKCMTCGVCLEACPNVNSKSNFIGPAPL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
SQVRLFNAHPTGAMHKAERLRTIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTT
HHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCHH
IQMFRDFFGSDEV
HHHHHHHHCCCCC
>Mature Secondary Structure 
SENKTVRFIITRQDRPDSAPYEEEFVIPYRPNMNVISALMEIRRNPVNAKGEKTTPVVW
CCCCEEEEEEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
EMNCLEEVCGACSMVINGKPRQACAALIDQLEQPIRLEPMRTFPVIRDLAIDRSRMFDAL
EHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KRVKAWIPIDGTYDLGPGPRMPERKRQWAYELSKCMTCGVCLEACPNVNSKSNFIGPAPL
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
SQVRLFNAHPTGAMHKAERLRTIMGDGGLANCGNSQNCVQSCPKGIPLTTSIAALNRDTT
HHEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHCCCHH
IQMFRDFFGSDEV
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]