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The map label for this gene is comGA [H]

Identifier: 138896011

GI number: 138896011

Start: 2489088

End: 2490287

Strand: Reverse

Name: comGA [H]

Synonym: GTNG_2374

Alternate gene names: 138896011

Gene position: 2490287-2489088 (Counterclockwise)

Preceding gene: 138896014

Following gene: 138896010

Centisome position: 70.14

GC content: 53.58

Gene sequence:

>1200_bases
TTGTCACTATTGGCGGCGAGTCGGACAAAATTCAAAAAATGTTCACGAAAAATTTTTTCGACAAGCAGCAGGAAAACGAG
CAATATCTGTCGAAATACAAAGCAATCTGTCGAAAGGAGGGAATATGTTCTGGATGATATCGAACAAGTAGCGAACCGTC
TCCTCGCCGAAGCGGTGCAACGCCGCGCCTCTGACCTTCATCTCGTCCCGCGCCGACATGATGCGATCATTCGCCTCCGC
CTTGACGGTATGCTCATCGATGTTGGTACAATCTCGAAAGAAACCGCTGAACGCGTCATCGTCCATTTCAAATTTTTGGC
TGGCATGGATATTGGCGAACGCCGTCGTCCGCAAAGCGGCGCGATGGAAGTGAATGAGTCCGGGGAAACGGTGTATTTGC
GCTTATCCACGCTGCCGACGCTTTATGATGAAAGCCTCGTCATCCGCCTTCTACCGCAGCGCTTTTCGCTGCCGCTTCGT
GAACTATCCTTATTTTCCCACTCCACCGCACGATTGTTTTCCTTTATGCAGCAGCCACAAGGACTCGTGTTGCTGACCGG
CCCAACCGGGTCGGGAAAGACGACGACATTGTATACGCTTCTCGACGTTTGCCAAGCGGAAAGACAACGTAACATTATCA
CGTTGGAAGATCCGATTGAAAAACGGAATGATCGGTTTTTGCAAGTGCAGATCAATGAAAAAGCAGGTATCACGTATGCA
GCCAGCTTGAAAGCCGCTTTGCGCCATGACCCGGATGTGTTAATGGTCGGCGAGATCCGCGACCATGATACGGCAGCGAT
CGCCGTACGATCAGCGTTGACAGGGCACTTGGTGGTATCGACCATGCATGCTGCTGATGCAGTCGGCGCAGTGTATCGGC
TCCATGAGTTCGGGGTGTCTCCCGGCGACTTGGCTGAGACGTTGCTTGCTGTTTCGGCGCAGCGTCTTGTTGAGCTTCGC
TGCCCGCTATGCGGTGACAATTGCCATCCGGCTTGTCGTCGGCTTCAACGAAGACGGCGTGCTGCCGTTCATGAGTTGCT
TTACGGCTCAGCGCTCTTTGATGTCATCCGTTCGCTGTCGGGGGAAGGCGAGCAACGGCTCCGCCCACATCTGACATTAG
CACGCCTCATCCGCAAAGGAATCGCACTCGGGTATTTGCCGACTCGCGCGCTTGAACTTGTCGGAGGGGGAGAACGATGA

Upstream 100 bases:

>100_bases
CACGTTTGTAATTTTTAACGTTTGTTCCATCGGGTTTCCCTCCTAAATAAATCATTGATACGGTTATTATAATGAAATGG
GTCAAAGCAAGGAATGATTT

Downstream 100 bases:

>100_bases
AGAAGAAAACGTGGCCGCTTGCTGAACAAGCATTGTTTTTTGCTCGACTTGGCCGGCTGCTTGAGCGCGGCTATCCGCTC
GGACAAGCGCTCGAATTTTT

Product: ComG operon protein 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSLLAASRTKFKKCSRKIFSTSSRKTSNICRNTKQSVERREYVLDDIEQVANRLLAEAVQRRASDLHLVPRRHDAIIRLR
LDGMLIDVGTISKETAERVIVHFKFLAGMDIGERRRPQSGAMEVNESGETVYLRLSTLPTLYDESLVIRLLPQRFSLPLR
ELSLFSHSTARLFSFMQQPQGLVLLTGPTGSGKTTTLYTLLDVCQAERQRNIITLEDPIEKRNDRFLQVQINEKAGITYA
ASLKAALRHDPDVLMVGEIRDHDTAAIAVRSALTGHLVVSTMHAADAVGAVYRLHEFGVSPGDLAETLLAVSAQRLVELR
CPLCGDNCHPACRRLQRRRRAAVHELLYGSALFDVIRSLSGEGEQRLRPHLTLARLIRKGIALGYLPTRALELVGGGER

Sequences:

>Translated_399_residues
MSLLAASRTKFKKCSRKIFSTSSRKTSNICRNTKQSVERREYVLDDIEQVANRLLAEAVQRRASDLHLVPRRHDAIIRLR
LDGMLIDVGTISKETAERVIVHFKFLAGMDIGERRRPQSGAMEVNESGETVYLRLSTLPTLYDESLVIRLLPQRFSLPLR
ELSLFSHSTARLFSFMQQPQGLVLLTGPTGSGKTTTLYTLLDVCQAERQRNIITLEDPIEKRNDRFLQVQINEKAGITYA
ASLKAALRHDPDVLMVGEIRDHDTAAIAVRSALTGHLVVSTMHAADAVGAVYRLHEFGVSPGDLAETLLAVSAQRLVELR
CPLCGDNCHPACRRLQRRRRAAVHELLYGSALFDVIRSLSGEGEQRLRPHLTLARLIRKGIALGYLPTRALELVGGGER
>Mature_398_residues
SLLAASRTKFKKCSRKIFSTSSRKTSNICRNTKQSVERREYVLDDIEQVANRLLAEAVQRRASDLHLVPRRHDAIIRLRL
DGMLIDVGTISKETAERVIVHFKFLAGMDIGERRRPQSGAMEVNESGETVYLRLSTLPTLYDESLVIRLLPQRFSLPLRE
LSLFSHSTARLFSFMQQPQGLVLLTGPTGSGKTTTLYTLLDVCQAERQRNIITLEDPIEKRNDRFLQVQINEKAGITYAA
SLKAALRHDPDVLMVGEIRDHDTAAIAVRSALTGHLVVSTMHAADAVGAVYRLHEFGVSPGDLAETLLAVSAQRLVELRC
PLCGDNCHPACRRLQRRRRAAVHELLYGSALFDVIRSLSGEGEQRLRPHLTLARLIRKGIALGYLPTRALELVGGGER

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=338, Percent_Identity=37.2781065088757, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1786296, Length=321, Percent_Identity=39.5638629283489, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082188, Length=198, Percent_Identity=38.3838383838384, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 44588; Mature: 44457

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLAASRTKFKKCSRKIFSTSSRKTSNICRNTKQSVERREYVLDDIEQVANRLLAEAVQ
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRASDLHLVPRRHDAIIRLRLDGMLIDVGTISKETAERVIVHFKFLAGMDIGERRRPQSG
HHHCCCEECCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AMEVNESGETVYLRLSTLPTLYDESLVIRLLPQRFSLPLRELSLFSHSTARLFSFMQQPQ
CEEECCCCCEEEEEEECCCCHHCCHHHHHHCHHHHCCCHHHHHHHCCHHHHHHHHHHCCC
GLVLLTGPTGSGKTTTLYTLLDVCQAERQRNIITLEDPIEKRNDRFLQVQINEKAGITYA
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHCCCCCEEEEEECCCCCEEHH
ASLKAALRHDPDVLMVGEIRDHDTAAIAVRSALTGHLVVSTMHAADAVGAVYRLHEFGVS
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGDLAETLLAVSAQRLVELRCPLCGDNCHPACRRLQRRRRAAVHELLYGSALFDVIRSLS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEGEQRLRPHLTLARLIRKGIALGYLPTRALELVGGGER
CCCHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SLLAASRTKFKKCSRKIFSTSSRKTSNICRNTKQSVERREYVLDDIEQVANRLLAEAVQ
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRASDLHLVPRRHDAIIRLRLDGMLIDVGTISKETAERVIVHFKFLAGMDIGERRRPQSG
HHHCCCEECCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AMEVNESGETVYLRLSTLPTLYDESLVIRLLPQRFSLPLRELSLFSHSTARLFSFMQQPQ
CEEECCCCCEEEEEEECCCCHHCCHHHHHHCHHHHCCCHHHHHHHCCHHHHHHHHHHCCC
GLVLLTGPTGSGKTTTLYTLLDVCQAERQRNIITLEDPIEKRNDRFLQVQINEKAGITYA
CEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEECCCHHCCCCCEEEEEECCCCCEEHH
ASLKAALRHDPDVLMVGEIRDHDTAAIAVRSALTGHLVVSTMHAADAVGAVYRLHEFGVS
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGDLAETLLAVSAQRLVELRCPLCGDNCHPACRRLQRRRRAAVHELLYGSALFDVIRSLS
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEGEQRLRPHLTLARLIRKGIALGYLPTRALELVGGGER
CCCHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]