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The map label for this gene is yqhT [H]

Identifier: 138895981

GI number: 138895981

Start: 2459670

End: 2460731

Strand: Reverse

Name: yqhT [H]

Synonym: GTNG_2342

Alternate gene names: 138895981

Gene position: 2460731-2459670 (Counterclockwise)

Preceding gene: 138895982

Following gene: 138895980

Centisome position: 69.31

GC content: 51.69

Gene sequence:

>1062_bases
ATGGAAAAGCTGGAAAAACTTCGGGCGCTTCTTGAGGAGCAGCATATTGATGGGCTTTTAGTGACAAACGGCTACAATCG
ACGTTACATCACTGGGTTCACCGGCACGGCCGGCGTCGCGATTGTCAGCCGTGAAGGGGCGGTTTTTATTACAGATTTCC
GCTATGTCGAACAAGCATCCAAACAAGTCGAAGGCTTTGAGATTGTTCAACATAGCGGGCCGATCATTGAGGAAATTGCG
AAGCAAGTAAAGCGGCTTGGTATCGGAAAGCTTGGCTTCGAGCAGGAACATGTAACGTATGCGGCATATAAAGCGTATGA
GGAAGCGATCAGCGCCGAGCTTGTGCCCACGGCTCATGTAGTGGAAAAGTTGCGCTTGATTAAGTCGGAAGCAGAGATTA
AGATATTAAAGGAAGCAGCGGAAATCGCCGATGCAGCATTTGCCCATATTTTGTCGTTCATCCGTCCGGGTGTCAAAGAA
ATCGAAGTAGCGAATGAGCTCGAGTTTTTTATGCGCAAGCAAGGAGCGTCTTCTTCTTCCTTTGAGACGATCGTCGCGTC
CGGTTACCGTTCGGCGTTGCCGCACGGGGTGGCGTCAGAGAAAACGATTGAGCGCGGCGAGCTTGTCACGCTTGATTTCG
GGGCTTACTACAAAGGATATTGTTCCGATATCACAAGGACGGTTGCCGTCGGCGAAATCAACGACGAACTGAAAACGATT
TATGATATCGTCCTTGAGGCGCAGCGGCGCGGTATGGACGGTCTTAAGGCAGGCATGACCGGCAAAGAGGCTGATGCGTT
AACGCGCGATTATATCCGCGAAAAAGGGTACGGCGACTATTTCGGCCATTCGACGGGCCATGGCATTGGTCTTGAGATTC
ACGAAGGGCCGACGCTTTCGTTCCGTTCTGATGTGGTGCTCGAGCCGGGCATGGTCGTCACCGTCGAGCCGGGCATTTAT
ATCCCGGGACTTGGCGGGGTGCGCATTGAAGACGACACAGTCATTACTGGCGACGGGAACGAAGCGCTCACTCATTCGCC
GAAAGAACTAATCATTTTATAA

Upstream 100 bases:

>100_bases
TGGCGCCTCCTTTGGCATGATCGTAGCTGAAAAGCCCCCATTTCATGGTCTACTGACGCGTGGGGGAGAGGGCAAATTCA
CGGGAAGAGGAGAATGAAGG

Downstream 100 bases:

>100_bases
CGGATTGCGTGAGGAGGAATTTCAGTCAATGATTTCAGTGAACGATTTTCGCACAGGGCTTACGATTGAGGTCGACGGCG
AGATTTGGCGCGTCCTTGAG

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEKLEKLRALLEEQHIDGLLVTNGYNRRYITGFTGTAGVAIVSREGAVFITDFRYVEQASKQVEGFEIVQHSGPIIEEIA
KQVKRLGIGKLGFEQEHVTYAAYKAYEEAISAELVPTAHVVEKLRLIKSEAEIKILKEAAEIADAAFAHILSFIRPGVKE
IEVANELEFFMRKQGASSSSFETIVASGYRSALPHGVASEKTIERGELVTLDFGAYYKGYCSDITRTVAVGEINDELKTI
YDIVLEAQRRGMDGLKAGMTGKEADALTRDYIREKGYGDYFGHSTGHGIGLEIHEGPTLSFRSDVVLEPGMVVTVEPGIY
IPGLGGVRIEDDTVITGDGNEALTHSPKELIIL

Sequences:

>Translated_353_residues
MEKLEKLRALLEEQHIDGLLVTNGYNRRYITGFTGTAGVAIVSREGAVFITDFRYVEQASKQVEGFEIVQHSGPIIEEIA
KQVKRLGIGKLGFEQEHVTYAAYKAYEEAISAELVPTAHVVEKLRLIKSEAEIKILKEAAEIADAAFAHILSFIRPGVKE
IEVANELEFFMRKQGASSSSFETIVASGYRSALPHGVASEKTIERGELVTLDFGAYYKGYCSDITRTVAVGEINDELKTI
YDIVLEAQRRGMDGLKAGMTGKEADALTRDYIREKGYGDYFGHSTGHGIGLEIHEGPTLSFRSDVVLEPGMVVTVEPGIY
IPGLGGVRIEDDTVITGDGNEALTHSPKELIIL
>Mature_353_residues
MEKLEKLRALLEEQHIDGLLVTNGYNRRYITGFTGTAGVAIVSREGAVFITDFRYVEQASKQVEGFEIVQHSGPIIEEIA
KQVKRLGIGKLGFEQEHVTYAAYKAYEEAISAELVPTAHVVEKLRLIKSEAEIKILKEAAEIADAAFAHILSFIRPGVKE
IEVANELEFFMRKQGASSSSFETIVASGYRSALPHGVASEKTIERGELVTLDFGAYYKGYCSDITRTVAVGEINDELKTI
YDIVLEAQRRGMDGLKAGMTGKEADALTRDYIREKGYGDYFGHSTGHGIGLEIHEGPTLSFRSDVVLEPGMVVTVEPGIY
IPGLGGVRIEDDTVITGDGNEALTHSPKELIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=262, Percent_Identity=35.1145038167939, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI260593665, Length=289, Percent_Identity=28.3737024221453, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI149589008, Length=289, Percent_Identity=28.3737024221453, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI264681563, Length=223, Percent_Identity=33.6322869955157, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI260593663, Length=265, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI93141226, Length=267, Percent_Identity=31.0861423220974, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI264681565, Length=220, Percent_Identity=31.3636363636364, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI164420681, Length=230, Percent_Identity=23.9130434782609, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40385867, Length=205, Percent_Identity=22.9268292682927, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=41.7827298050139, Blast_Score=282, Evalue=2e-77,
Organism=Escherichia coli, GI1789275, Length=263, Percent_Identity=34.2205323193916, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790282, Length=281, Percent_Identity=24.5551601423488, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786364, Length=204, Percent_Identity=24.5098039215686, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=26.530612244898, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71989583, Length=250, Percent_Identity=24.8, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17509539, Length=364, Percent_Identity=25.5494505494505, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321118, Length=304, Percent_Identity=25.3289473684211, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322999, Length=236, Percent_Identity=28.8135593220339, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323273, Length=229, Percent_Identity=28.3842794759825, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920384, Length=276, Percent_Identity=30.0724637681159, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21357079, Length=295, Percent_Identity=30.1694915254237, Blast_Score=101, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38717; Mature: 38717

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLEKLRALLEEQHIDGLLVTNGYNRRYITGFTGTAGVAIVSREGAVFITDFRYVEQAS
CCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEECCCEEEEECHHHHHHHH
KQVEGFEIVQHSGPIIEEIAKQVKRLGIGKLGFEQEHVTYAAYKAYEEAISAELVPTAHV
HHCCCHHEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
VEKLRLIKSEAEIKILKEAAEIADAAFAHILSFIRPGVKEIEVANELEFFMRKQGASSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
FETIVASGYRSALPHGVASEKTIERGELVTLDFGAYYKGYCSDITRTVAVGEINDELKTI
HHHHHHHCHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEECCCHHHHHHH
YDIVLEAQRRGMDGLKAGMTGKEADALTRDYIREKGYGDYFGHSTGHGIGLEIHEGPTLS
HHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCC
FRSDVVLEPGMVVTVEPGIYIPGLGGVRIEDDTVITGDGNEALTHSPKELIIL
CCCCEEECCCEEEEECCCEEECCCCCEEECCCEEEECCCCCCCCCCCCCEEEC
>Mature Secondary Structure
MEKLEKLRALLEEQHIDGLLVTNGYNRRYITGFTGTAGVAIVSREGAVFITDFRYVEQAS
CCHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEECCCEEEEECHHHHHHHH
KQVEGFEIVQHSGPIIEEIAKQVKRLGIGKLGFEQEHVTYAAYKAYEEAISAELVPTAHV
HHCCCHHEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
VEKLRLIKSEAEIKILKEAAEIADAAFAHILSFIRPGVKEIEVANELEFFMRKQGASSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
FETIVASGYRSALPHGVASEKTIERGELVTLDFGAYYKGYCSDITRTVAVGEINDELKTI
HHHHHHHCHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHEEECCCHHHHHHH
YDIVLEAQRRGMDGLKAGMTGKEADALTRDYIREKGYGDYFGHSTGHGIGLEIHEGPTLS
HHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCC
FRSDVVLEPGMVVTVEPGIYIPGLGGVRIEDDTVITGDGNEALTHSPKELIIL
CCCCEEECCCEEEEECCCEEECCCCCEEECCCEEEECCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]