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The map label for this gene is fur [H]

Identifier: 138895889

GI number: 138895889

Start: 2365623

End: 2366108

Strand: Reverse

Name: fur [H]

Synonym: GTNG_2248

Alternate gene names: 138895889

Gene position: 2366108-2365623 (Counterclockwise)

Preceding gene: 138895890

Following gene: 138895888

Centisome position: 66.64

GC content: 49.38

Gene sequence:

>486_bases
ATGGGAGGTGAATGGCGAGGGAGGAATGAAAAAATGGAAGATCGTGTGGAACGAATTAAGAAGCAGCTGCACTCGGCCGG
CTACAAGCTGACGCCGCAGCGGGAAGCGACGGTAAGAGTCCTGCTTGAACATGAAGAAGACCATTTAAGCGCTGAAGACG
TCTACCTCCTCGTAAAAGAAAAATCTCCAGAGATCGGGCTGGCGACCGTTTATCGGACGCTTGAACTGCTAACCGAGCTG
AAAATCGTTGATAAAATCAATTTCGGGGACGGGGTATCGCGCTATGACCTTCGCAAAGAAGGGGCGGCGCATTTCCATCA
CCATCTTGTCTGCCTCGAGTGCGGATCGGTGGCGGAAATTGAAGAAGATTTGCTTGAGGACGTCGAAGCGATTGTTGAAC
GGGAATGGAAGTTTAAAATTAAAGATCACCACTTGACGTTTCACGGCATTTGCCACCGCTGCCAGCAAAAACATGAAGAA
AAGTAA

Upstream 100 bases:

>100_bases
AAATGGGTGGTTAATTTAATAAATATTATTATATAATAATCATTATTTTTATCTTATAATAGTCATTTTACTTTGATACT
TACCTTATACATTTGCTATA

Downstream 100 bases:

>100_bases
AAACCTTTTCCAACGGGAAAGGTTTTTTTGCGTATAAATAGGGAAACAAATGGCATATCCTCATACTAGCAAATGGGCAA
GCAGCCGATGGGGAGGGTGC

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MGGEWRGRNEKMEDRVERIKKQLHSAGYKLTPQREATVRVLLEHEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTEL
KIVDKINFGDGVSRYDLRKEGAAHFHHHLVCLECGSVAEIEEDLLEDVEAIVEREWKFKIKDHHLTFHGICHRCQQKHEE
K

Sequences:

>Translated_161_residues
MGGEWRGRNEKMEDRVERIKKQLHSAGYKLTPQREATVRVLLEHEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTEL
KIVDKINFGDGVSRYDLRKEGAAHFHHHLVCLECGSVAEIEEDLLEDVEAIVEREWKFKIKDHHLTFHGICHRCQQKHEE
K
>Mature_160_residues
GGEWRGRNEKMEDRVERIKKQLHSAGYKLTPQREATVRVLLEHEEDHLSAEDVYLLVKEKSPEIGLATVYRTLELLTELK
IVDKINFGDGVSRYDLRKEGAAHFHHHLVCLECGSVAEIEEDLLEDVEAIVEREWKFKIKDHHLTFHGICHRCQQKHEEK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=140, Percent_Identity=36.4285714285714, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18848; Mature: 18716

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGEWRGRNEKMEDRVERIKKQLHSAGYKLTPQREATVRVLLEHEEDHLSAEDVYLLVKE
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEECCCCCCCCCCEEEEEEC
KSPEIGLATVYRTLELLTELKIVDKINFGDGVSRYDLRKEGAAHFHHHLVCLECGSVAEI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHEEECCCHHHH
EEDLLEDVEAIVEREWKFKIKDHHLTFHGICHRCQQKHEEK
HHHHHHHHHHHHHCHHCEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GGEWRGRNEKMEDRVERIKKQLHSAGYKLTPQREATVRVLLEHEEDHLSAEDVYLLVKE
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEECCCCCCCCCCEEEEEEC
KSPEIGLATVYRTLELLTELKIVDKINFGDGVSRYDLRKEGAAHFHHHLVCLECGSVAEI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHEEECCCHHHH
EEDLLEDVEAIVEREWKFKIKDHHLTFHGICHRCQQKHEEK
HHHHHHHHHHHHHCHHCEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]