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The map label for this gene is xerD [H]

Identifier: 138895887

GI number: 138895887

Start: 2364406

End: 2365302

Strand: Reverse

Name: xerD [H]

Synonym: GTNG_2246

Alternate gene names: 138895887

Gene position: 2365302-2364406 (Counterclockwise)

Preceding gene: 138895888

Following gene: 138895886

Centisome position: 66.62

GC content: 51.62

Gene sequence:

>897_bases
TTGGAACATGAATTAAAGGATTTCTTGCATTATTTGACGGTAGAGCGGAACTTGGCGCACAATACGATTATTTCGTATGA
ACGGGATTTAAAGAAATATGTCCACTACTTGCGCGAGGTCGAGCAGCTTGAGGCGTGGGGCGAAGTCGAGCGTCTGCATA
TTCTTCATTTTTTAAAGTTTTTAAGCGAGCAAGGGCAGTCAGCAAGGACGATTGCTCGACATTTGGCGTCGATTCGTTCG
TTTCATCAGTTTTTGCTGCGGGAGAAAATGGCGGCGCAAGACCCGACGGTCCATATCGAAACGCCGCAGTTTGAGCGGAC
GCTGCCAAAAGTGCTGTCCGTCGAAGAAGTCGAAGCGCTCCTGGCGGCGCCACAGACGAATACGCCGTTCGGCTTGCGTG
ACAAGGCGATGCTTGAGGTGCTATATGCGACCGGCATGCGCGTCAGCGAGCTTGTACAGCTCAATTTAGGTGACGTGCAT
TTGACAATGGGGTTTGTCCGCTGCTATGGGAAAGGGCGGAAAGAGCGGATTGTCCCGATCGGACGGATGGCGCTTGAAGC
ACTTGCCCGCTATTTGGAGTATGGGCGCCCGCAGCTTGTAAATCCGCGCAAGCGGGCAACGGAGGCATTGTTTTTGAACC
ATTACGGCCAGCGCCTGACGCGACAAGGGTTTTGGAAAATTTTAAAACGTCTTTCCAAAGAAGCGGGCATTGAAAAAGAG
TTGACGCCTCACACGCTCCGTCATTCATTTGCGACTCATCTGCTTGAGAACGGAGCCGATTTGCGCGCTGTCCAAGAACT
GCTTGGGCACGCTGATATTTCGACGACGCAGATGTATACGCACGTAACGAAAACGCGCCTGAAAGACGTGTATAAACAGT
ATCATCCTCGTGCCTAG

Upstream 100 bases:

>100_bases
ACCGGAAGGATCGGCGGTGAAAGTATCGACGATCGAACACACGCCTCCGGACTGGCTCAACCGGCTATTATTTTTTTATC
GCGATGGGGAGTAGAGAACA

Downstream 100 bases:

>100_bases
TCACGGCGCACCGCTGATGCTAGGCACACTTCTATTGATCTAGTTGTCAGACTTCTGACCAATACAATAAGGGCGTGTTT
TACCGGAAATATGGGAACGA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MEHELKDFLHYLTVERNLAHNTIISYERDLKKYVHYLREVEQLEAWGEVERLHILHFLKFLSEQGQSARTIARHLASIRS
FHQFLLREKMAAQDPTVHIETPQFERTLPKVLSVEEVEALLAAPQTNTPFGLRDKAMLEVLYATGMRVSELVQLNLGDVH
LTMGFVRCYGKGRKERIVPIGRMALEALARYLEYGRPQLVNPRKRATEALFLNHYGQRLTRQGFWKILKRLSKEAGIEKE
LTPHTLRHSFATHLLENGADLRAVQELLGHADISTTQMYTHVTKTRLKDVYKQYHPRA

Sequences:

>Translated_298_residues
MEHELKDFLHYLTVERNLAHNTIISYERDLKKYVHYLREVEQLEAWGEVERLHILHFLKFLSEQGQSARTIARHLASIRS
FHQFLLREKMAAQDPTVHIETPQFERTLPKVLSVEEVEALLAAPQTNTPFGLRDKAMLEVLYATGMRVSELVQLNLGDVH
LTMGFVRCYGKGRKERIVPIGRMALEALARYLEYGRPQLVNPRKRATEALFLNHYGQRLTRQGFWKILKRLSKEAGIEKE
LTPHTLRHSFATHLLENGADLRAVQELLGHADISTTQMYTHVTKTRLKDVYKQYHPRA
>Mature_298_residues
MEHELKDFLHYLTVERNLAHNTIISYERDLKKYVHYLREVEQLEAWGEVERLHILHFLKFLSEQGQSARTIARHLASIRS
FHQFLLREKMAAQDPTVHIETPQFERTLPKVLSVEEVEALLAAPQTNTPFGLRDKAMLEVLYATGMRVSELVQLNLGDVH
LTMGFVRCYGKGRKERIVPIGRMALEALARYLEYGRPQLVNPRKRATEALFLNHYGQRLTRQGFWKILKRLSKEAGIEKE
LTPHTLRHSFATHLLENGADLRAVQELLGHADISTTQMYTHVTKTRLKDVYKQYHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=48.8135593220339, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=37.2881355932203, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1790768, Length=185, Percent_Identity=30.8108108108108, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790767, Length=190, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34697; Mature: 34697

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHELKDFLHYLTVERNLAHNTIISYERDLKKYVHYLREVEQLEAWGEVERLHILHFLKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEQGQSARTIARHLASIRSFHQFLLREKMAAQDPTVHIETPQFERTLPKVLSVEEVEAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHH
LAAPQTNTPFGLRDKAMLEVLYATGMRVSELVQLNLGDVHLTMGFVRCYGKGRKERIVPI
HHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHH
GRMALEALARYLEYGRPQLVNPRKRATEALFLNHYGQRLTRQGFWKILKRLSKEAGIEKE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTPHTLRHSFATHLLENGADLRAVQELLGHADISTTQMYTHVTKTRLKDVYKQYHPRA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEHELKDFLHYLTVERNLAHNTIISYERDLKKYVHYLREVEQLEAWGEVERLHILHFLKF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEQGQSARTIARHLASIRSFHQFLLREKMAAQDPTVHIETPQFERTLPKVLSVEEVEAL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHH
LAAPQTNTPFGLRDKAMLEVLYATGMRVSELVQLNLGDVHLTMGFVRCYGKGRKERIVPI
HHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHH
GRMALEALARYLEYGRPQLVNPRKRATEALFLNHYGQRLTRQGFWKILKRLSKEAGIEKE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LTPHTLRHSFATHLLENGADLRAVQELLGHADISTTQMYTHVTKTRLKDVYKQYHPRA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]