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The map label for this gene is cobU [H]

Identifier: 138895835

GI number: 138895835

Start: 2317245

End: 2317802

Strand: Reverse

Name: cobU [H]

Synonym: GTNG_2194

Alternate gene names: 138895835

Gene position: 2317802-2317245 (Counterclockwise)

Preceding gene: 138895836

Following gene: 138895834

Centisome position: 65.28

GC content: 58.06

Gene sequence:

>558_bases
ATGATCGTGTTTGTGAGCGGCGCGGTGCGCAGCGGCAAAAGCGAAGTGGCGGAAGCATGTGCTAGGAGTCTCGCTCATGG
CGGCCGTCTCCATTATCTTGCCACTGCGCAGGCGACGGATGAGGAAATGGCGGCGCGCATCCGTCGCCATCAAGAGCGGC
GCACAGCCAGTGGGGCGTACTGGATGGTGTGGGAAGGGCCGGCACGTCTTGAGCAGCTTGCCGGGTCGCTTCGTCCTTCC
GACGTTGTGCTCATTGATTGTTTAACCATGTGGCTGGCGAATGACTTGTTTGTCGGTGACAGTTGGCGAACGGAGGAGGC
GTCATTCGCCATCGCCGGCCGTCTGTTAGATGACGTGCGGAGTTTAGCGGATGCTTGCCGCGCTGTTGTCATCGTTTCAA
ACGAACTGTTTTCTGGCGGTGTACCGACTGATCCTGGCACGTTTTGCTATATGAAAACGCTCGGTTGGCTTCATCAACAG
TTGGTTGCAGAAGCGGCGGTTGCCGCGGTGGTTGAATGCGGTCTCGTTCGAGTGAAAAAAGGGCGGTGGCCGCAATGA

Upstream 100 bases:

>100_bases
CGATGAATTTCCCCGGACTTGACGGCCGCTATGTTCGGCTGGCCGTCAAAACACCGATGGAAAACGACCGGCTTCTCGAA
GCGCTTGCGGGGTGGGATGG

Downstream 100 bases:

>100_bases
GGCAGATGTGGAACGGCTGGCTGTTGGCGTTGCAGTTGTTTACCGTCATTCCAATTCGGCGATCAATTGAATGGAATGAC
ATCCATGTCCGTTGGCTCGT

Product: cobinamide kinase, cobinamide phosphateguanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIVFVSGAVRSGKSEVAEACARSLAHGGRLHYLATAQATDEEMAARIRRHQERRTASGAYWMVWEGPARLEQLAGSLRPS
DVVLIDCLTMWLANDLFVGDSWRTEEASFAIAGRLLDDVRSLADACRAVVIVSNELFSGGVPTDPGTFCYMKTLGWLHQQ
LVAEAAVAAVVECGLVRVKKGRWPQ

Sequences:

>Translated_185_residues
MIVFVSGAVRSGKSEVAEACARSLAHGGRLHYLATAQATDEEMAARIRRHQERRTASGAYWMVWEGPARLEQLAGSLRPS
DVVLIDCLTMWLANDLFVGDSWRTEEASFAIAGRLLDDVRSLADACRAVVIVSNELFSGGVPTDPGTFCYMKTLGWLHQQ
LVAEAAVAAVVECGLVRVKKGRWPQ
>Mature_185_residues
MIVFVSGAVRSGKSEVAEACARSLAHGGRLHYLATAQATDEEMAARIRRHQERRTASGAYWMVWEGPARLEQLAGSLRPS
DVVLIDCLTMWLANDLFVGDSWRTEEASFAIAGRLLDDVRSLADACRAVVIVSNELFSGGVPTDPGTFCYMKTLGWLHQQ
LVAEAAVAAVVECGLVRVKKGRWPQ

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=187, Percent_Identity=33.6898395721925, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20204; Mature: 20204

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFVSGAVRSGKSEVAEACARSLAHGGRLHYLATAQATDEEMAARIRRHQERRTASGAY
CEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCE
WMVWEGPARLEQLAGSLRPSDVVLIDCLTMWLANDLFVGDSWRTEEASFAIAGRLLDDVR
EEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHH
SLADACRAVVIVSNELFSGGVPTDPGTFCYMKTLGWLHQQLVAEAAVAAVVECGLVRVKK
HHHHHHHEEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
GRWPQ
CCCCC
>Mature Secondary Structure
MIVFVSGAVRSGKSEVAEACARSLAHGGRLHYLATAQATDEEMAARIRRHQERRTASGAY
CEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCE
WMVWEGPARLEQLAGSLRPSDVVLIDCLTMWLANDLFVGDSWRTEEASFAIAGRLLDDVR
EEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHH
SLADACRAVVIVSNELFSGGVPTDPGTFCYMKTLGWLHQQLVAEAAVAAVVECGLVRVKK
HHHHHHHEEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
GRWPQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]