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The map label for this gene is aroB [H]

Identifier: 138895784

GI number: 138895784

Start: 2271202

End: 2272302

Strand: Reverse

Name: aroB [H]

Synonym: GTNG_2140

Alternate gene names: 138895784

Gene position: 2272302-2271202 (Counterclockwise)

Preceding gene: 138895785

Following gene: 138895783

Centisome position: 64.0

GC content: 55.4

Gene sequence:

>1101_bases
ATGATGGAACGGACGATTGAAACGGCGACGAAACAATATCCGCTTCTGCTGGGTGATGGGGCGGCTCGCGCGTTGCCGCG
CCTGCTCCGCTCGCTCGCCTGTCCACCGGGGACGAAGCTGTTTATCATTACCGACGATGCGGTGGCGCCGCTTTATTTGG
ATGAGGTGCGCGCCATGCTTGCCGCTGCTGAGTATGACGTATATGCCTATATCATCCCGAGCGGAGAGGCGGCCAAGTCA
TTCGACAACTATTACGCCTGCCAAACAGCGGCGCTCCAGTGCAGCTTAGACCGCCGTTCAGTCATTATCGCGCTTGGCGG
CGGCGTTGTTGGCGATTTAGCCGGATTTGTCGCGGCCACCTATATGCGTGGCATCCGCTATATTCAAATGCCGACAACAC
TCTTGGCTCATGACAGCGCCGTCGGCGGCAAAGTGGCGATTAACCATCCGCTTGGTAAAAATATGATCGGTGCCTTCCAT
CAGCCGGAAGCGGTTGTGTATGATACGACTTTTTTGCGCACGCTGCCTGAGCGTGAACTCCGGTCGGGGTTTGCCGAAGT
GATCAAGCATGCGCTCATCCGTGACCGCCGCTTTTATGAATGGCTGCGTGCGGAAGTGAAGACGCTCGCCGATTTGCGCG
GCGAAGCGCTCACCTATTGTATTGAAAAAGGCATCGATATTAAGGCGTCTATCGTACGTGAAGATGAAAAAGAAACCAGC
GTGCGTGCCCATTTAAATTTTGGTCATACGCTCGGCCATGCGCTTGAAAGTGAACTTGGTTACGGTACGCTCACCCATGG
GGAAGCAGTCGCCATCGGCATGCTGTTTGCCGTGTTTGTCAGTGAACGGCTTTATGGCCACTCGTTTGCTGAGCACCGCT
TTGCCGAATGGTTTGCCCGATACGGTTTTCCGGTGTCGCTGCCGACGACGGTGGAGGCCGATCGGTTGCTTGAGAAAATG
AAAGGTGACAAAAAAGCATACGCCGGGACGGTGCGGATGGTGCTCTTGCGCGAGATCGGCGACGTCGAAGTCGTGGAATT
AGAAGATGATAAGCTGCTCGCTTGGCTAGATGAGTTCGCCAAACAGGGGGGAGGACGATGA

Upstream 100 bases:

>100_bases
AAGTGGCGGCGGCGATCGTTGAGCAATTCGGGCAAGATCGGATTGACTTGATCAAAGAAAACATTGAGCGCGCTCGCCGC
TATGCAAGGGAGTTTTAACG

Downstream 100 bases:

>100_bases
TTCGCGGCATTCGCGGAGCGATTACGGTTGAACAAAATGAAGCCGAAGAAATCGTGACGGCTACCGAAATACTGTTGCGT
GAAATGATTGAGGCGAACGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MMERTIETATKQYPLLLGDGAARALPRLLRSLACPPGTKLFIITDDAVAPLYLDEVRAMLAAAEYDVYAYIIPSGEAAKS
FDNYYACQTAALQCSLDRRSVIIALGGGVVGDLAGFVAATYMRGIRYIQMPTTLLAHDSAVGGKVAINHPLGKNMIGAFH
QPEAVVYDTTFLRTLPERELRSGFAEVIKHALIRDRRFYEWLRAEVKTLADLRGEALTYCIEKGIDIKASIVREDEKETS
VRAHLNFGHTLGHALESELGYGTLTHGEAVAIGMLFAVFVSERLYGHSFAEHRFAEWFARYGFPVSLPTTVEADRLLEKM
KGDKKAYAGTVRMVLLREIGDVEVVELEDDKLLAWLDEFAKQGGGR

Sequences:

>Translated_366_residues
MMERTIETATKQYPLLLGDGAARALPRLLRSLACPPGTKLFIITDDAVAPLYLDEVRAMLAAAEYDVYAYIIPSGEAAKS
FDNYYACQTAALQCSLDRRSVIIALGGGVVGDLAGFVAATYMRGIRYIQMPTTLLAHDSAVGGKVAINHPLGKNMIGAFH
QPEAVVYDTTFLRTLPERELRSGFAEVIKHALIRDRRFYEWLRAEVKTLADLRGEALTYCIEKGIDIKASIVREDEKETS
VRAHLNFGHTLGHALESELGYGTLTHGEAVAIGMLFAVFVSERLYGHSFAEHRFAEWFARYGFPVSLPTTVEADRLLEKM
KGDKKAYAGTVRMVLLREIGDVEVVELEDDKLLAWLDEFAKQGGGR
>Mature_366_residues
MMERTIETATKQYPLLLGDGAARALPRLLRSLACPPGTKLFIITDDAVAPLYLDEVRAMLAAAEYDVYAYIIPSGEAAKS
FDNYYACQTAALQCSLDRRSVIIALGGGVVGDLAGFVAATYMRGIRYIQMPTTLLAHDSAVGGKVAINHPLGKNMIGAFH
QPEAVVYDTTFLRTLPERELRSGFAEVIKHALIRDRRFYEWLRAEVKTLADLRGEALTYCIEKGIDIKASIVREDEKETS
VRAHLNFGHTLGHALESELGYGTLTHGEAVAIGMLFAVFVSERLYGHSFAEHRFAEWFARYGFPVSLPTTVEADRLLEKM
KGDKKAYAGTVRMVLLREIGDVEVVELEDDKLLAWLDEFAKQGGGR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=350, Percent_Identity=48.2857142857143, Blast_Score=291, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6320332, Length=353, Percent_Identity=36.2606232294618, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40512; Mature: 40512

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMERTIETATKQYPLLLGDGAARALPRLLRSLACPPGTKLFIITDDAVAPLYLDEVRAML
CCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
AAAEYDVYAYIIPSGEAAKSFDNYYACQTAALQCSLDRRSVIIALGGGVVGDLAGFVAAT
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCHHHHHHHHHHHH
YMRGIRYIQMPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYDTTFLRTLPEREL
HHHCCEEEECCHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEEHHHHHHCCHHHH
RSGFAEVIKHALIRDRRFYEWLRAEVKTLADLRGEALTYCIEKGIDIKASIVREDEKETS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCHHHH
VRAHLNFGHTLGHALESELGYGTLTHGEAVAIGMLFAVFVSERLYGHSFAEHRFAEWFAR
EEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
YGFPVSLPTTVEADRLLEKMKGDKKAYAGTVRMVLLREIGDVEVVELEDDKLLAWLDEFA
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
KQGGGR
HHCCCC
>Mature Secondary Structure
MMERTIETATKQYPLLLGDGAARALPRLLRSLACPPGTKLFIITDDAVAPLYLDEVRAML
CCCCHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
AAAEYDVYAYIIPSGEAAKSFDNYYACQTAALQCSLDRRSVIIALGGGVVGDLAGFVAAT
HHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCHHHHHHHHHHHH
YMRGIRYIQMPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYDTTFLRTLPEREL
HHHCCEEEECCHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEEHHHHHHCCHHHH
RSGFAEVIKHALIRDRRFYEWLRAEVKTLADLRGEALTYCIEKGIDIKASIVREDEKETS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCHHHH
VRAHLNFGHTLGHALESELGYGTLTHGEAVAIGMLFAVFVSERLYGHSFAEHRFAEWFAR
EEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
YGFPVSLPTTVEADRLLEKMKGDKKAYAGTVRMVLLREIGDVEVVELEDDKLLAWLDEFA
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHH
KQGGGR
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA