| Definition | Geobacillus thermodenitrificans NG80-2 chromosome, complete genome. |
|---|---|
| Accession | NC_009328 |
| Length | 3,550,319 |
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The map label for this gene is fabG [H]
Identifier: 138895679
GI number: 138895679
Start: 2153445
End: 2154209
Strand: Reverse
Name: fabG [H]
Synonym: GTNG_2035
Alternate gene names: 138895679
Gene position: 2154209-2153445 (Counterclockwise)
Preceding gene: 138895680
Following gene: 138895678
Centisome position: 60.68
GC content: 57.52
Gene sequence:
>765_bases ATGTTCTCAGGAAAAGTCATCGTGGTAACCGGTGCGAGCCGGGGCATCGGTGCGGCCATTGCCCGCGCGTTTGCCCGGGA ACATGGAACGGTCATCGTCAACTATTTGCAAAATCAGCAGGCAGCGGAACAAGTGGCCGCCGCCTGCGTTGAACTTGGCG GCGATGCTTGGGCCGTTCAGGCCGATGTCACCTCGGAATCAGCGGTCAAGCAGTTGATTGAGCAAGTGATGATGGAGACA GGGAAAATCGATGTCATCGTCAACAATGCGTTTGCGCCGTATACATTTGACCCAGATGAGCGCAAACTGGCGTGGGAGCT CGCGTGGGAAGATTATCAGGCGCAAATCGACGGAGCGCTGCGCTCGACCTATTATATGTGTCAGGCGGTGATTCCGATCA TGAAAAAGCAGGGCGGGGGGAGCATTGTTAATATCGTGACAGACTTAGTCGCCCGCCCGGTCGTCCCGTACCATGACTAC ACAACGGCGAAAGCGGCGCTCGTCGGTTACAGCCGCAACTTAGCGGCGGAGCTCGGTCCGTTTGGCATCCGCGTCAATTG TGTCGCTCCTGGCTTGGTTTACCCGACGGACGCCAGCCGGCGGACAAAGGAGGAAGTGAAGGAAATGCTGATCGCCCAAA CGCCGCTGCGGCGAATCGCCACTCCTGAAGATGTTGCCGGGCCGGTTCTCTTTTTAGCGTCTGATTGGAGCCGCTTTATG ACCGGACAGACGTTGTTTGTCGACGGCGGGCTCATCATGCGCTAG
Upstream 100 bases:
>100_bases CACGTATAAACAGCTAGGCTTGATTAAAAACGACATCAACATGGCGGAAGTGGTTACCAATGAATTGCTTCCGAAACAAT AATGGAGGACGAAAATGGGG
Downstream 100 bases:
>100_bases CGCTGCCGGCATCTTGAATATGCCTACGTTTCACCAGCTGCCCTCGAGAACAAAGGGCAGTTTTTTTTTGTAGAATTTGG TGATTTATTATGGTATGATA
Product: 3-oxoacyl-(acyl carrier protein) reductase-like protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MFSGKVIVVTGASRGIGAAIARAFAREHGTVIVNYLQNQQAAEQVAAACVELGGDAWAVQADVTSESAVKQLIEQVMMET GKIDVIVNNAFAPYTFDPDERKLAWELAWEDYQAQIDGALRSTYYMCQAVIPIMKKQGGGSIVNIVTDLVARPVVPYHDY TTAKAALVGYSRNLAAELGPFGIRVNCVAPGLVYPTDASRRTKEEVKEMLIAQTPLRRIATPEDVAGPVLFLASDWSRFM TGQTLFVDGGLIMR
Sequences:
>Translated_254_residues MFSGKVIVVTGASRGIGAAIARAFAREHGTVIVNYLQNQQAAEQVAAACVELGGDAWAVQADVTSESAVKQLIEQVMMET GKIDVIVNNAFAPYTFDPDERKLAWELAWEDYQAQIDGALRSTYYMCQAVIPIMKKQGGGSIVNIVTDLVARPVVPYHDY TTAKAALVGYSRNLAAELGPFGIRVNCVAPGLVYPTDASRRTKEEVKEMLIAQTPLRRIATPEDVAGPVLFLASDWSRFM TGQTLFVDGGLIMR >Mature_254_residues MFSGKVIVVTGASRGIGAAIARAFAREHGTVIVNYLQNQQAAEQVAAACVELGGDAWAVQADVTSESAVKQLIEQVMMET GKIDVIVNNAFAPYTFDPDERKLAWELAWEDYQAQIDGALRSTYYMCQAVIPIMKKQGGGSIVNIVTDLVARPVVPYHDY TTAKAALVGYSRNLAAELGPFGIRVNCVAPGLVYPTDASRRTKEEVKEMLIAQTPLRRIATPEDVAGPVLFLASDWSRFM TGQTLFVDGGLIMR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=35.1351351351351, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=36.0323886639676, Blast_Score=120, Evalue=1e-27, Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=30.6513409961686, Blast_Score=118, Evalue=7e-27, Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=31.5384615384615, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=30.859375, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=31.9066147859922, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=31.7829457364341, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=29.6875, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI210032110, Length=195, Percent_Identity=29.7435897435897, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI126723191, Length=191, Percent_Identity=31.9371727748691, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=29.6153846153846, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=28.2700421940928, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI33667109, Length=208, Percent_Identity=29.8076923076923, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503301, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=26.9035532994924, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI209862901, Length=226, Percent_Identity=32.3008849557522, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI19923983, Length=226, Percent_Identity=32.3008849557522, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI40254986, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI4504505, Length=242, Percent_Identity=29.3388429752066, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=34.5238095238095, Blast_Score=130, Evalue=7e-32, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=30.46875, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI87082100, Length=261, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=32.156862745098, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=28.0155642023346, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=29.8449612403101, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=31.0077519379845, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=29.1187739463602, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1789378, Length=246, Percent_Identity=29.6747967479675, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=31.7269076305221, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=29.004329004329, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787545, Length=258, Percent_Identity=29.8449612403101, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1789057, Length=266, Percent_Identity=28.1954887218045, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787891, Length=250, Percent_Identity=25.6, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787526, Length=248, Percent_Identity=26.6129032258064, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=32.9588014981273, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=34.6715328467153, Blast_Score=116, Evalue=9e-27, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=36.3295880149813, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=34.2960288808664, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=28.0155642023346, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=32.5842696629214, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=28.4615384615385, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17565030, Length=272, Percent_Identity=33.8235294117647, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560150, Length=278, Percent_Identity=32.0143884892086, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=31.203007518797, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=32.2834645669291, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=32.4909747292419, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=32.4528301886792, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=29.4776119402985, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=31.4393939393939, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=28.4046692607004, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=30.5970149253731, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=30.9701492537313, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=29.8892988929889, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=29.1828793774319, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=31.9548872180451, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=27.8810408921933, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17508651, Length=256, Percent_Identity=26.5625, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=30.6201550387597, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=27.843137254902, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI71982365, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI71997099, Length=269, Percent_Identity=28.996282527881, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17557780, Length=231, Percent_Identity=27.7056277056277, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=26.8482490272374, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17558628, Length=201, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561272, Length=259, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17568967, Length=225, Percent_Identity=28.8888888888889, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=29.5719844357977, Blast_Score=98, Evalue=1e-21, Organism=Saccharomyces cerevisiae, GI6322861, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=8e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=254, Percent_Identity=27.9527559055118, Blast_Score=71, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=35.2941176470588, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=28.6821705426357, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=33.59375, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=34.8837209302326, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.5490196078431, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=30.7086614173228, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30.8, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=30.9803921568627, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI21357673, Length=260, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI18859837, Length=227, Percent_Identity=30.3964757709251, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=28.8973384030418, Blast_Score=72, Evalue=3e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27575; Mature: 27575
Theoretical pI: Translated: 5.10; Mature: 5.10
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFSGKVIVVTGASRGIGAAIARAFAREHGTVIVNYLQNQQAAEQVAAACVELGGDAWAVQ CCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHCCCCEEEEE ADVTSESAVKQLIEQVMMETGKIDVIVNNAFAPYTFDPDERKLAWELAWEDYQAQIDGAL ECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHH RSTYYMCQAVIPIMKKQGGGSIVNIVTDLVARPVVPYHDYTTAKAALVGYSRNLAAELGP HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHCCC FGIRVNCVAPGLVYPTDASRRTKEEVKEMLIAQTPLRRIATPEDVAGPVLFLASDWSRFM CCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHCCCEEEEECCHHHHH TGQTLFVDGGLIMR CCCEEEECCCEECC >Mature Secondary Structure MFSGKVIVVTGASRGIGAAIARAFAREHGTVIVNYLQNQQAAEQVAAACVELGGDAWAVQ CCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHCCCCEEEEE ADVTSESAVKQLIEQVMMETGKIDVIVNNAFAPYTFDPDERKLAWELAWEDYQAQIDGAL ECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCEEEEEEHHHHHHHHHHHHH RSTYYMCQAVIPIMKKQGGGSIVNIVTDLVARPVVPYHDYTTAKAALVGYSRNLAAELGP HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHCCC FGIRVNCVAPGLVYPTDASRRTKEEVKEMLIAQTPLRRIATPEDVAGPVLFLASDWSRFM CCEEEEEECCCEEECCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHCCCEEEEECCHHHHH TGQTLFVDGGLIMR CCCEEEECCCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10192388; 10684935; 10871362 [H]