| Definition | Geobacillus thermodenitrificans NG80-2 chromosome, complete genome. |
|---|---|
| Accession | NC_009328 |
| Length | 3,550,319 |
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The map label for this gene is mtlR [H]
Identifier: 138895498
GI number: 138895498
Start: 1967327
End: 1969276
Strand: Reverse
Name: mtlR [H]
Synonym: GTNG_1846
Alternate gene names: 138895498
Gene position: 1969276-1967327 (Counterclockwise)
Preceding gene: 138895499
Following gene: 138895497
Centisome position: 55.47
GC content: 53.23
Gene sequence:
>1950_bases TTGCGGCACTACGGACTTGAGCTGGTGAAAAAAGCAGGGGTCGGCATTCGTCTCGTTGGGGAAGAGAAACAAAAGCAGGC GCTGGCTGCCGAGCTGCTTCATCTTTCTCACCGTGAATATACGCCGGAAGAACGGCAGCTGATGATTTTAATCGCCTTGT TAGAAGCCGGTGAGCCAGTGAAACTCGTCTCACTGGCGAACGACTTGAACGTCACGGTTGCCACTGTCAGTTTGGATTTG GACAAATTGGAACAAACGCTCAAAGCGTACGGGCTTTCGCTCATTCGCAAGCGCGGGTACGGGGTGGAGCTTGCCGGTTC CGAATCAGCGAAACGGCGTCTCATTAGCGAACTGCTATTCCGCCATGTCAATGAACACGAGTTTTTGGAGCTGATGAAAG AGACGATTCAGAAGCGGTCAGATGATCCGCTTGATACGGTGGCGGAAAAGCTGCTCGGGCTTGTGGATCGAAAAAAGCTC GCCATCATTGAGAAACAAATCGAGCAAGTAAAAGAAAAGCTCCCATTTACGATGGCGGACAGTTCGTACATCGCCTTCGT CGTCCATTTGGCGCTCGCCATCGAGCGCATCAAGCGGGGGGAAGCGATTCATTTCGACCCGCACGATTTGCGGACGCTCC AGGCAGCGAAAGAATTTGCGATCGCCGAAATGCTCGCTGAATCGTTGGAAAGAGCTTTTGGCATTAACATTCCAAAAGAA GAAATCGGCTATATGACGATGCATTTAATGGGAGCGAAATGGCGCAGCCGTCAAGGAATGATGATGGAGGAGCCGAGTTT GGTTGTCGGCATGAAAGCGCAACAGCTCATTCGTTTCGTCAGCCGTGAGCTTGGAGTCGATCTGTCCACCGACCGCACGC TATACGAAGATCTCGTCGTTCACTTAAAACCGGCGTTGTACCGTTTAGAGCACGGGATGGGGGTCGCCAATCCGCTCCTG GATCAAATTAGGAAAGACTATCCGGAGCTGTTTGCGGTTGTCGCCAATGGAACGAAGCAGCTGTTTGGCTACATTCCGGT GCCAGAGGAGGAGATCGGTTACTTGGTGCTCCATTTTGCGGCTGCGCTCATGCGGGAGAAAAAAGGTTGGCGGGCGCTCG TTATTTGTTCGAGCGGGCTCGGAACGGCGAAAATTTTAGCGACAAGGCTGAAAAGAGCGATTCCGGATATCACTGTCATG GAGCAGGCGTCTGTCTTTGAATTGAAAAAGAAAGATTTGCGGGCGTACGACCTCGTCATTTCGACCGTGCCGCTTCCGGA AGAGTACGGGCCGCATGTCATCGTCAGTCCAATGCTCACCGAAGAGGAAGCGCGGGCGATCCGCCAGCGGTTGGAACGGA AAACAGCTGTGGAAAAGCGGAGGGAAAACGAGTCCATTGCACGTCGAAATCGGTCGATGCTCGCCACGATGAAAGCCGTT CGACGCATCAGTGAGACGATCATCCATCTTTTGGACGGTTTTCTCCTTGAGATGGTCACTTGTCGTTCGATCCATGAATT ATTGATGAACGCGTGCCGTCGCCTCGAGCGAAACGGGGTTCTTGTCGATGCCAAAGTCGTCATCGAGGAGCTGGAGCGCC GCGAGTCGCTAGGCGGGCTCGGCGTTCCCGGCACGAAGCTGGCGCTTTACCACGCCCGCAGTTTCTCTGTCCTTCGTCCA TCGCTGACGATGTACCGGCTTGATGAACCACAAACGGTGGCAGGCATGGACGGGGAGCCGATGGAAGTAAACACGGTTGT ACTGCTTCTTGGCCCTGCCGATGCGGATGAAGAGATGCTTTCCGTATTGAGCCAAGTGAGCACTTTGCTCGTCAAGGACG AACAAAGCACGGCCACGTTGGCTCGTGGCGGCGAAAACGAGGTATATTCGCTCGTTAGCAGCCATTTAGAACAATTTTTC GATCATTATTGGACAACAACGAAGGAGTGA
Upstream 100 bases:
>100_bases GTTAGTAGGAGGGCGAGAGATAACAGTCGGCGAGCTGGCCGAAGAGCTGAATGTCAGCACCCGCACGATCCACCGCGATT TGCAAGGCCTCGAATCCGTT
Downstream 100 bases:
>100_bases AGGTCATGTTGGCTTATTCAATTTTAAAGAAAGAAAACATTGTGCTAAATGCTCAACCAAAAACGAAAGAAGAAGCCATT CGCCTAGCTGGCGAAGTGCT
Product: putative transcriptional regulator
Products: NA
Alternate protein names: Mannitol operon transcriptional activator; Mtl operon transcriptional activator; Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]
Number of amino acids: Translated: 649; Mature: 649
Protein sequence:
>649_residues MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDL DKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKL AIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLL DQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVM EQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRP SLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFF DHYWTTTKE
Sequences:
>Translated_649_residues MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDL DKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKL AIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLL DQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVM EQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRP SLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFF DHYWTTTKE >Mature_649_residues MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPVKLVSLANDLNVTVATVSLDL DKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLFRHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKL AIIEKQIEQVKEKLPFTMADSSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLL DQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFAAALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVM EQASVFELKKKDLRAYDLVISTVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGLGVPGTKLALYHARSFSVLRP SLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEMLSVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFF DHYWTTTKE
Specific function: Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol [H]
COG id: COG3711
COG function: function code K; Transcriptional antiterminator
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIB type-2 domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR013196 - InterPro: IPR007737 - InterPro: IPR011608 - InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR011991 [H]
Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 73287; Mature: 73287
Theoretical pI: Translated: 6.71; Mature: 6.71
Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPV CCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCE KLVSLANDLNVTVATVSLDLDKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLF EEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH RHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKLAIIEKQIEQVKEKLPFTMAD HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC SSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE CHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVV HHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH HLKPALYRLEHGMGVANPLLDQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFA HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH AALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVMEQASVFELKKKDLRAYDLVI HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHE STVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV ECCCCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCC GVPGTKLALYHARSFSVLRPSLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEML CCCCCCEEEEECCCHHHHCCCCEEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCHHHH SVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFFDHYWTTTKE HHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MRHYGLELVKKAGVGIRLVGEEKQKQALAAELLHLSHREYTPEERQLMILIALLEAGEPV CCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCE KLVSLANDLNVTVATVSLDLDKLEQTLKAYGLSLIRKRGYGVELAGSESAKRRLISELLF EEEEECCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH RHVNEHEFLELMKETIQKRSDDPLDTVAEKLLGLVDRKKLAIIEKQIEQVKEKLPFTMAD HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECC SSYIAFVVHLALAIERIKRGEAIHFDPHDLRTLQAAKEFAIAEMLAESLERAFGINIPKE CHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH EIGYMTMHLMGAKWRSRQGMMMEEPSLVVGMKAQQLIRFVSRELGVDLSTDRTLYEDLVV HHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH HLKPALYRLEHGMGVANPLLDQIRKDYPELFAVVANGTKQLFGYIPVPEEEIGYLVLHFA HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH AALMREKKGWRALVICSSGLGTAKILATRLKRAIPDITVMEQASVFELKKKDLRAYDLVI HHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHE STVPLPEEYGPHVIVSPMLTEEEARAIRQRLERKTAVEKRRENESIARRNRSMLATMKAV ECCCCCHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH RRISETIIHLLDGFLLEMVTCRSIHELLMNACRRLERNGVLVDAKVVIEELERRESLGGL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCCC GVPGTKLALYHARSFSVLRPSLTMYRLDEPQTVAGMDGEPMEVNTVVLLLGPADADEEML CCCCCCEEEEECCCHHHHCCCCEEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCHHHH SVLSQVSTLLVKDEQSTATLARGGENEVYSLVSSHLEQFFDHYWTTTKE HHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]