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The map label for this gene is ycgO [H]

Identifier: 138895479

GI number: 138895479

Start: 1943961

End: 1945436

Strand: Reverse

Name: ycgO [H]

Synonym: GTNG_1827

Alternate gene names: 138895479

Gene position: 1945436-1943961 (Counterclockwise)

Preceding gene: 138895480

Following gene: 138895478

Centisome position: 54.8

GC content: 45.46

Gene sequence:

>1476_bases
ATGATTGAGTCACCGAAAAGGGAGAGGCTTTTGACAAAAGAGGATGGGGGAATGGCGATGAGTACACTGGATACAGGGGT
TCTTTTATGTTATTTTCTCGTATTGGTTGTCGCAGGGATTTTGGGGGCAAGGCGTGCGAAGACAGCGGAAGATTTTGCAT
TGGCGGGACGAAATCTTGGGCTATTTGTTTATCTTGGCTGCCTGTCCGCTGTGATTTTGGGTGGTGCTTCAACGATTGGG
ACGGCGAAGTTAGGATATCAATTTGGGATTTCAGGCATGTGGTTTGTCTTTATGATCGGCTTGGGCATCACGGTGCTCGG
TTTGTTTTTTACGAATCAAATTTACGGCGCCAATGTGACAACGATTAGTGAGCTCCTTGGGCGCCGGTACAACCAGGAAA
CTCGTTTGATCAGCGCGTTAGTTGCGGCCATTTATACGTTGATGGTGTCTGTGACACAAGTGATTGGGATGGGCACCATC
ATTCATGCCGTTTTAGGTTGGGACATGACTGTTTCGATGTTAGTCGGGGGCGGAATTGTGTTGTTTTACACGATTCTCGG
AGGAATGTGGAGCGTGACGATGACGGACATCATTCAGTTTATCGTCATGACCATTGGTATTTTCTTTATTATGTTGCCGA
TGAGTTTGTCCCATGTCGGCGGATGGGAATCACTTTTGGACCAATTGCCAGCATCCCATTTTGATCTCACCTCCATGGGA
TGGGCGAATATTTTCCAATATTTCTTGCTCTATACTTTAGGAATGGTTGTATCACAAGATATTTGGCAGCGAGTGTTTAC
GGCAAGAACGAAGAAAATTGCTCGGAGTGGTGCGGTATATGCTGGGCTATACAGCGTTGCCTATGCACTAGTGTTAAGCG
TCATCGGTATGTGCGGCGTGATTGTTTTCCCGAATATTGGCGATCCGCAAAATGTATTTGCCAGCATGTCATTACAGATG
TTGCCACACGGTTTATTAGGGCTCATTTTGGCAAGCGTATGTTCCGCTCTTATGTCCACTGCCTCAGGAACGTTGCTTGC
TTCCTCTACCCTCTTATCACATGATATTTTGAAGCAGTATTGGTTAAAAGATATCAGCGATCAGAAGTTTGTTCTGTTGT
CTAGAATCATGACATTAACGATTGGCATCATTGCGATTGCCTTTGCCATTTGGATTCAAGACGTGCTTGTCGCGTTGGAT
GTCGCCTATGCCATTTTGTCAGGAGCCATTTTCGTCCCATTGATTCTCGGTTTTTTCTGGAAACGTGTTACAGCGAAAGC
CGGTTTTTATTCCATCGTCCTTAGTTCCATCGTTGTGTTAGTTGGGCTGGCGGTAGAGGGATTAAGTTCAACCTATCCGA
TTATGTATGGAATTGGAGCGAGCATCGTTTCCATCATTGTTTTGTCCTATTTATTCCCGTCTTCAAATTTGGATACAGGC
AATGAGGCTTTAGAGGAGCGTCAAAGCGTCCTTTGA

Upstream 100 bases:

>100_bases
TTTAGGAGGGGGCTCACCATCCAACGGTTCTTGAACGAGAGATGGAGAGCACCTTCTATCATTTTCTTCAGCTGAAGGAG
CCTCTTTCTTGATCGCATTG

Downstream 100 bases:

>100_bases
CCATTCAAACGGTTTTCGGATTGGAAAGAGGATTCCTTTCAACAAATGACGAACTAAAAATGATGGACATGATATTTTAC
GCAATACAAGTTTAGAGGGG

Product: sodium:solute symport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MIESPKRERLLTKEDGGMAMSTLDTGVLLCYFLVLVVAGILGARRAKTAEDFALAGRNLGLFVYLGCLSAVILGGASTIG
TAKLGYQFGISGMWFVFMIGLGITVLGLFFTNQIYGANVTTISELLGRRYNQETRLISALVAAIYTLMVSVTQVIGMGTI
IHAVLGWDMTVSMLVGGGIVLFYTILGGMWSVTMTDIIQFIVMTIGIFFIMLPMSLSHVGGWESLLDQLPASHFDLTSMG
WANIFQYFLLYTLGMVVSQDIWQRVFTARTKKIARSGAVYAGLYSVAYALVLSVIGMCGVIVFPNIGDPQNVFASMSLQM
LPHGLLGLILASVCSALMSTASGTLLASSTLLSHDILKQYWLKDISDQKFVLLSRIMTLTIGIIAIAFAIWIQDVLVALD
VAYAILSGAIFVPLILGFFWKRVTAKAGFYSIVLSSIVVLVGLAVEGLSSTYPIMYGIGASIVSIIVLSYLFPSSNLDTG
NEALEERQSVL

Sequences:

>Translated_491_residues
MIESPKRERLLTKEDGGMAMSTLDTGVLLCYFLVLVVAGILGARRAKTAEDFALAGRNLGLFVYLGCLSAVILGGASTIG
TAKLGYQFGISGMWFVFMIGLGITVLGLFFTNQIYGANVTTISELLGRRYNQETRLISALVAAIYTLMVSVTQVIGMGTI
IHAVLGWDMTVSMLVGGGIVLFYTILGGMWSVTMTDIIQFIVMTIGIFFIMLPMSLSHVGGWESLLDQLPASHFDLTSMG
WANIFQYFLLYTLGMVVSQDIWQRVFTARTKKIARSGAVYAGLYSVAYALVLSVIGMCGVIVFPNIGDPQNVFASMSLQM
LPHGLLGLILASVCSALMSTASGTLLASSTLLSHDILKQYWLKDISDQKFVLLSRIMTLTIGIIAIAFAIWIQDVLVALD
VAYAILSGAIFVPLILGFFWKRVTAKAGFYSIVLSSIVVLVGLAVEGLSSTYPIMYGIGASIVSIIVLSYLFPSSNLDTG
NEALEERQSVL
>Mature_491_residues
MIESPKRERLLTKEDGGMAMSTLDTGVLLCYFLVLVVAGILGARRAKTAEDFALAGRNLGLFVYLGCLSAVILGGASTIG
TAKLGYQFGISGMWFVFMIGLGITVLGLFFTNQIYGANVTTISELLGRRYNQETRLISALVAAIYTLMVSVTQVIGMGTI
IHAVLGWDMTVSMLVGGGIVLFYTILGGMWSVTMTDIIQFIVMTIGIFFIMLPMSLSHVGGWESLLDQLPASHFDLTSMG
WANIFQYFLLYTLGMVVSQDIWQRVFTARTKKIARSGAVYAGLYSVAYALVLSVIGMCGVIVFPNIGDPQNVFASMSLQM
LPHGLLGLILASVCSALMSTASGTLLASSTLLSHDILKQYWLKDISDQKFVLLSRIMTLTIGIIAIAFAIWIQDVLVALD
VAYAILSGAIFVPLILGFFWKRVTAKAGFYSIVLSSIVVLVGLAVEGLSSTYPIMYGIGASIVSIIVLSYLFPSSNLDTG
NEALEERQSVL

Specific function: Catalyzes the sodium-dependent uptake of extracellular amino acids [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=367, Percent_Identity=26.158038147139, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI157671931, Length=374, Percent_Identity=24.5989304812834, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI14140236, Length=502, Percent_Identity=22.9083665338645, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI109659836, Length=488, Percent_Identity=22.5409836065574, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI11141885, Length=393, Percent_Identity=23.9185750636132, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI310128183, Length=499, Percent_Identity=24.8496993987976, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI17941285, Length=459, Percent_Identity=25.0544662309368, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI109659839, Length=504, Percent_Identity=21.8253968253968, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4507031, Length=483, Percent_Identity=22.360248447205, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI110835708, Length=509, Percent_Identity=22.5933202357564, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4507033, Length=468, Percent_Identity=23.2905982905983, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI206597483, Length=378, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI167466278, Length=366, Percent_Identity=22.6775956284153, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI256985183, Length=379, Percent_Identity=22.9551451187335, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787251, Length=452, Percent_Identity=23.4513274336283, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790503, Length=482, Percent_Identity=21.1618257261411, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790113, Length=416, Percent_Identity=23.5576923076923, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082237, Length=440, Percent_Identity=23.4090909090909, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17539284, Length=414, Percent_Identity=23.6714975845411, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI115533094, Length=434, Percent_Identity=23.7327188940092, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648033, Length=456, Percent_Identity=25.6578947368421, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356865, Length=456, Percent_Identity=25.6578947368421, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24645928, Length=357, Percent_Identity=25.2100840336134, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573698, Length=412, Percent_Identity=22.5728155339806, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221459584, Length=382, Percent_Identity=24.869109947644, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011851
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 52993; Mature: 52993

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]