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The map label for this gene is ttuB [H]

Identifier: 138895149

GI number: 138895149

Start: 1572368

End: 1573672

Strand: Direct

Name: ttuB [H]

Synonym: GTNG_1487

Alternate gene names: 138895149

Gene position: 1572368-1573672 (Clockwise)

Preceding gene: 138895148

Following gene: 138895150

Centisome position: 44.29

GC content: 43.45

Gene sequence:

>1305_bases
GTGAAAGGGACATTGGCGAAATCGCGGTGGTACCGCCTGATTCCGGTCGTATTTATTACGTATAGTTTGGCTTATCTTGA
TCGAGCGAATTACGGATTTGGCGCAGCAGGAGGTTTGGCCGAAGACTTAAACATTTCCGCTGCCACCTCGTCTTTGTTAG
GGTCGCTGTTTTTCCTTGGATATTTTTTATTTCAGATACCAGGCGCCCATTACGCAGAAAAGAAGAGTGCGAAGAAATTG
ATTTTCTGGTCGTTAATTCTTTGGGGCGGACTGGCGAGTGCGACGGGATTAGTCAGCGATATTCATTGGTTGATGGTAAT
TCGCTTTTTATTAGGGGTTGTCGAAAGCGCTGTCATGCCTGCGATGCTTGTCTTTTTAAGCCATTGGTTTACGAAAGAAG
AGAGATCTCGGGCAAATACGTTTTTAATTCTTGGCAACCCAGTGACGGTATTATGGATGTCCATTGTATCAGGCTATTTG
ATTGAATCATTCGGTTGGAGATGGATGTTTGTTATTGAAGGAGTTCCTGCTATCATATGGGCATTTATTTGGTGGAAGTT
GGTTGAAGATGAACCGAAGATGGCCAAATGGTTGACAGGAGAAGAGAAAGAGCAATTGCAGAAGCAGCTAGAACAGGAGC
AACGAGGATTAAAACCGGTGAAAAATTATCGTGAAGCATTTCGGTCCAAAATTGTCATTCTATTAAGTTTGCAATATGCG
TTGTGGAGTATTGGAGTATATGGGTTTGTGATGTGGTTGCCATCCATTATTAAAGCGGCGCCGCATATGGATATTGTTAC
AACAGGGTGGCTGTCATCAGTGCCTTACATCTTTGCGGTTATTTTTATGATTGTTTCTTCTTACTTCTCTGATAAAACAT
TAAATCGTTCAGGATTTGTATGGCCCTCTTTATTAATTGGTGCCATTGCGTTTTACGCTTCGTATGCCATCGGGACGAAC
CATTTTTGGATTTCATTCATCCTGTTGGTCGTTGCTGGAGCGGCTATGTATGCACCGTACGGACCATTTTTTGCGATCAT
TCCCGAGATTTTGCCTCGGAATGTCGCCGGTGGCGCGATGGCGTTAATTAACAGCATGGGAGCGCTTGGGTCATTTGCAG
GGTCGTATGTTGTTGGTTATTTAAACGGAGTTACTGGCGGATTTGGAGCATCGTATATTTTTATGGCAGCTTCATTGCTT
CTTGCATCATGGTTAACCATCATTGCTGTTAAAGGGGGCAATAAACAAAAAAAGGTGCCTGATGAGTGGGTTGCCCATCA
AGCACAAAAAAGCATTGGCAACTAA

Upstream 100 bases:

>100_bases
CCATCGGGGCGTTAGCCGTTCAGTCAGAAGGGGACAGTGATGGATATCCAACTCGACAACAGTTGGAACAGTTTATCAAC
ATTCGGGAGGAGGGCCTAGC

Downstream 100 bases:

>100_bases
ATATTATACTATAGATAACAGGTTCTTGCATAGTTAACGTATCATGAGGAGTACGTTCATTTTCGCTACAGCCGGCAGTC
AGGCATTCACTAGTCGGCTG

Product: 2-ketogluconate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKGTLAKSRWYRLIPVVFITYSLAYLDRANYGFGAAGGLAEDLNISAATSSLLGSLFFLGYFLFQIPGAHYAEKKSAKKL
IFWSLILWGGLASATGLVSDIHWLMVIRFLLGVVESAVMPAMLVFLSHWFTKEERSRANTFLILGNPVTVLWMSIVSGYL
IESFGWRWMFVIEGVPAIIWAFIWWKLVEDEPKMAKWLTGEEKEQLQKQLEQEQRGLKPVKNYREAFRSKIVILLSLQYA
LWSIGVYGFVMWLPSIIKAAPHMDIVTTGWLSSVPYIFAVIFMIVSSYFSDKTLNRSGFVWPSLLIGAIAFYASYAIGTN
HFWISFILLVVAGAAMYAPYGPFFAIIPEILPRNVAGGAMALINSMGALGSFAGSYVVGYLNGVTGGFGASYIFMAASLL
LASWLTIIAVKGGNKQKKVPDEWVAHQAQKSIGN

Sequences:

>Translated_434_residues
MKGTLAKSRWYRLIPVVFITYSLAYLDRANYGFGAAGGLAEDLNISAATSSLLGSLFFLGYFLFQIPGAHYAEKKSAKKL
IFWSLILWGGLASATGLVSDIHWLMVIRFLLGVVESAVMPAMLVFLSHWFTKEERSRANTFLILGNPVTVLWMSIVSGYL
IESFGWRWMFVIEGVPAIIWAFIWWKLVEDEPKMAKWLTGEEKEQLQKQLEQEQRGLKPVKNYREAFRSKIVILLSLQYA
LWSIGVYGFVMWLPSIIKAAPHMDIVTTGWLSSVPYIFAVIFMIVSSYFSDKTLNRSGFVWPSLLIGAIAFYASYAIGTN
HFWISFILLVVAGAAMYAPYGPFFAIIPEILPRNVAGGAMALINSMGALGSFAGSYVVGYLNGVTGGFGASYIFMAASLL
LASWLTIIAVKGGNKQKKVPDEWVAHQAQKSIGN
>Mature_434_residues
MKGTLAKSRWYRLIPVVFITYSLAYLDRANYGFGAAGGLAEDLNISAATSSLLGSLFFLGYFLFQIPGAHYAEKKSAKKL
IFWSLILWGGLASATGLVSDIHWLMVIRFLLGVVESAVMPAMLVFLSHWFTKEERSRANTFLILGNPVTVLWMSIVSGYL
IESFGWRWMFVIEGVPAIIWAFIWWKLVEDEPKMAKWLTGEEKEQLQKQLEQEQRGLKPVKNYREAFRSKIVILLSLQYA
LWSIGVYGFVMWLPSIIKAAPHMDIVTTGWLSSVPYIFAVIFMIVSSYFSDKTLNRSGFVWPSLLIGAIAFYASYAIGTN
HFWISFILLVVAGAAMYAPYGPFFAIIPEILPRNVAGGAMALINSMGALGSFAGSYVVGYLNGVTGGFGASYIFMAASLL
LASWLTIIAVKGGNKQKKVPDEWVAHQAQKSIGN

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI148743791, Length=248, Percent_Identity=24.1935483870968, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI6912666, Length=252, Percent_Identity=29.3650793650794, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI9966811, Length=378, Percent_Identity=23.2804232804233, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI9945322, Length=407, Percent_Identity=22.8501228501229, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI21322234, Length=396, Percent_Identity=23.989898989899, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI148728191, Length=191, Percent_Identity=23.5602094240838, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI154800443, Length=325, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI154350196, Length=367, Percent_Identity=22.6158038147139, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=376, Percent_Identity=27.9255319148936, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=23.0588235294118, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789152, Length=426, Percent_Identity=23.7089201877934, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI2367379, Length=276, Percent_Identity=23.5507246376812, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789515, Length=417, Percent_Identity=24.220623501199, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI2367193, Length=391, Percent_Identity=25.8312020460358, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533556, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554148, Length=354, Percent_Identity=24.8587570621469, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17554962, Length=344, Percent_Identity=23.546511627907, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=358, Percent_Identity=25.1396648044693, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=425, Percent_Identity=24.4705882352941, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560030, Length=296, Percent_Identity=20.9459459459459, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=288, Percent_Identity=22.5694444444444, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=288, Percent_Identity=22.5694444444444, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=288, Percent_Identity=22.5694444444444, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32565916, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193205400, Length=184, Percent_Identity=27.1739130434783, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=242, Percent_Identity=26.8595041322314, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=326, Percent_Identity=23.9263803680982, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580790, Length=376, Percent_Identity=25, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550460, Length=273, Percent_Identity=28.2051282051282, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24655255, Length=273, Percent_Identity=28.2051282051282, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24583789, Length=357, Percent_Identity=26.6106442577031, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584153, Length=359, Percent_Identity=24.2339832869081, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20130135, Length=307, Percent_Identity=25.4071661237785, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24655271, Length=307, Percent_Identity=25.7328990228013, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641682, Length=379, Percent_Identity=26.6490765171504, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24648416, Length=267, Percent_Identity=27.3408239700375, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356189, Length=267, Percent_Identity=27.3408239700375, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573708, Length=257, Percent_Identity=25.6809338521401, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573707, Length=257, Percent_Identity=25.6809338521401, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24653727, Length=377, Percent_Identity=24.4031830238727, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20130167, Length=238, Percent_Identity=26.4705882352941, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573299, Length=254, Percent_Identity=24.0157480314961, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129235, Length=357, Percent_Identity=25.7703081232493, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24639764, Length=254, Percent_Identity=24.8031496062992, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62484226, Length=262, Percent_Identity=25.1908396946565, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24658696, Length=239, Percent_Identity=24.2677824267782, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48214; Mature: 48214

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTLAKSRWYRLIPVVFITYSLAYLDRANYGFGAAGGLAEDLNISAATSSLLGSLFFLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
YFLFQIPGAHYAEKKSAKKLIFWSLILWGGLASATGLVSDIHWLMVIRFLLGVVESAVMP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVFLSHWFTKEERSRANTFLILGNPVTVLWMSIVSGYLIESFGWRWMFVIEGVPAIIW
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
AFIWWKLVEDEPKMAKWLTGEEKEQLQKQLEQEQRGLKPVKNYREAFRSKIVILLSLQYA
HHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LWSIGVYGFVMWLPSIIKAAPHMDIVTTGWLSSVPYIFAVIFMIVSSYFSDKTLNRSGFV
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
WPSLLIGAIAFYASYAIGTNHFWISFILLVVAGAAMYAPYGPFFAIIPEILPRNVAGGAM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHH
ALINSMGALGSFAGSYVVGYLNGVTGGFGASYIFMAASLLLASWLTIIAVKGGNKQKKVP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
DEWVAHQAQKSIGN
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKGTLAKSRWYRLIPVVFITYSLAYLDRANYGFGAAGGLAEDLNISAATSSLLGSLFFLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHH
YFLFQIPGAHYAEKKSAKKLIFWSLILWGGLASATGLVSDIHWLMVIRFLLGVVESAVMP
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVFLSHWFTKEERSRANTFLILGNPVTVLWMSIVSGYLIESFGWRWMFVIEGVPAIIW
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
AFIWWKLVEDEPKMAKWLTGEEKEQLQKQLEQEQRGLKPVKNYREAFRSKIVILLSLQYA
HHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LWSIGVYGFVMWLPSIIKAAPHMDIVTTGWLSSVPYIFAVIFMIVSSYFSDKTLNRSGFV
HHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
WPSLLIGAIAFYASYAIGTNHFWISFILLVVAGAAMYAPYGPFFAIIPEILPRNVAGGAM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHH
ALINSMGALGSFAGSYVVGYLNGVTGGFGASYIFMAASLLLASWLTIIAVKGGNKQKKVP
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
DEWVAHQAQKSIGN
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]