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The map label for this gene is serC [H]

Identifier: 138894233

GI number: 138894233

Start: 620499

End: 621587

Strand: Direct

Name: serC [H]

Synonym: GTNG_0559

Alternate gene names: 138894233

Gene position: 620499-621587 (Clockwise)

Preceding gene: 138894232

Following gene: 138894234

Centisome position: 17.48

GC content: 51.97

Gene sequence:

>1089_bases
ATGACAGTGGAACGCGTGTACAATTTTAACGCCGGCCCGTCGGCGCTGCCGTTGCCGGTACTCGAGCGGGCGCAAAAGGA
GCTACTCAACTTCCAGAATACTGGCATGTCGGTGATGGAATTAAGCCATCGCAGCAAGGAATATGACGCCGTCCACAATG
CGGCGAAAGAGCGGCTCAAGCGACTCCTCAACGTACCGGATGGCTATGACATTTTATTTTTGCAAGGTGGGGCGAGTCTG
CAGTTTTCGATGGTGCCGATGAATTTCCTCACCGAAGGGAAAATCGGCTGCTATGTTTTAACCGGTGCATGGTCGGAAAA
AGCGCTGAAAGAAGCGCAAAAAATCGGTTTGACGACGGTCGTCGCTTCAAGTAAGGAGGCGAACTACACGTATATTCCAT
CGTTGGACGACGTGAAATGGCCGAAAGATGCTTCCTACGTCCATATTACGTCCAACAACACTATTTTTGGTACACAATGG
AATGAGTTTCCAGACGTGCCGGTTGATCTTGTTGCTGATATGTCAAGTGATATTTTGAGCCGGCCGTTTGATGTCAGCAA
GTTTGCCTTGATTTACGCTGGAGCGCAAAAAAATCTTGGCCCGTCGGGAGTCACGGTCGTCATCATCCGCAACGATTTGC
TTGAACGAATTCCGGATGGGCTGCCGACGATGCTCGACTACCGGACGCACCAAAAAAGCAATTCGTTATACAACACACCA
CCGACGTTTGCGATTTATATGCTGTCGCTCGTGCTCGAATGGGTTGAAGAACAGGGCGGAGTGGCGGCAATCGAAGCGCG
CAACCAGCAAAAAGCAGCTGTGCTGTATGAGGCCATTGACGAAAGCGGAGGCTTTTACAAACCGCATGCGGAAAAAGGAA
GTCGCTCGCTCATGAACGTCACGTTCACACTGCCGAGTGAAGAACTGACGAAGGCATTCCTCGCAGAAGCGAAGGAGCGA
AACTTTGTCGGACTTGGTGGACACCGATCGGTTGGGGGCTGCCGAGCGTCGATTTACAACGCTGTACCGCTTGAGGCGTG
CGAGGCACTCGCGGCATTTATGAACGACTTCCGTCGCCGTTTTGCCTGA

Upstream 100 bases:

>100_bases
CATCATTTGAAAGCGCTTTTTCAAAAAATTCCCTTTCTTTTTTAAAAATTCGTGTTAGGATAATAATATCAAAGGGACTA
CCTGGAGAATAAAGTGAGGG

Downstream 100 bases:

>100_bases
AAATTTTTTCTTCACTTTTATACTGCAAAGTGATATAATGATAGAAAAATTCTCAAGCAAGAGAATAGGTGAGGAGAGAA
GAGGAGAGATGAGCATGAAT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTVERVYNFNAGPSALPLPVLERAQKELLNFQNTGMSVMELSHRSKEYDAVHNAAKERLKRLLNVPDGYDILFLQGGASL
QFSMVPMNFLTEGKIGCYVLTGAWSEKALKEAQKIGLTTVVASSKEANYTYIPSLDDVKWPKDASYVHITSNNTIFGTQW
NEFPDVPVDLVADMSSDILSRPFDVSKFALIYAGAQKNLGPSGVTVVIIRNDLLERIPDGLPTMLDYRTHQKSNSLYNTP
PTFAIYMLSLVLEWVEEQGGVAAIEARNQQKAAVLYEAIDESGGFYKPHAEKGSRSLMNVTFTLPSEELTKAFLAEAKER
NFVGLGGHRSVGGCRASIYNAVPLEACEALAAFMNDFRRRFA

Sequences:

>Translated_362_residues
MTVERVYNFNAGPSALPLPVLERAQKELLNFQNTGMSVMELSHRSKEYDAVHNAAKERLKRLLNVPDGYDILFLQGGASL
QFSMVPMNFLTEGKIGCYVLTGAWSEKALKEAQKIGLTTVVASSKEANYTYIPSLDDVKWPKDASYVHITSNNTIFGTQW
NEFPDVPVDLVADMSSDILSRPFDVSKFALIYAGAQKNLGPSGVTVVIIRNDLLERIPDGLPTMLDYRTHQKSNSLYNTP
PTFAIYMLSLVLEWVEEQGGVAAIEARNQQKAAVLYEAIDESGGFYKPHAEKGSRSLMNVTFTLPSEELTKAFLAEAKER
NFVGLGGHRSVGGCRASIYNAVPLEACEALAAFMNDFRRRFA
>Mature_361_residues
TVERVYNFNAGPSALPLPVLERAQKELLNFQNTGMSVMELSHRSKEYDAVHNAAKERLKRLLNVPDGYDILFLQGGASLQ
FSMVPMNFLTEGKIGCYVLTGAWSEKALKEAQKIGLTTVVASSKEANYTYIPSLDDVKWPKDASYVHITSNNTIFGTQWN
EFPDVPVDLVADMSSDILSRPFDVSKFALIYAGAQKNLGPSGVTVVIIRNDLLERIPDGLPTMLDYRTHQKSNSLYNTPP
TFAIYMLSLVLEWVEEQGGVAAIEARNQQKAAVLYEAIDESGGFYKPHAEKGSRSLMNVTFTLPSEELTKAFLAEAKERN
FVGLGGHRSVGGCRASIYNAVPLEACEALAAFMNDFRRRFA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=360, Percent_Identity=47.5, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=43.2584269662921, Blast_Score=280, Evalue=1e-75,
Organism=Escherichia coli, GI1787136, Length=359, Percent_Identity=44.8467966573816, Blast_Score=306, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17506897, Length=366, Percent_Identity=44.2622950819672, Blast_Score=305, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6324758, Length=397, Percent_Identity=40.0503778337531, Blast_Score=284, Evalue=1e-77,
Organism=Drosophila melanogaster, GI21356589, Length=360, Percent_Identity=45.8333333333333, Blast_Score=317, Evalue=6e-87,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40095; Mature: 39964

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVERVYNFNAGPSALPLPVLERAQKELLNFQNTGMSVMELSHRSKEYDAVHNAAKERLK
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHH
RLLNVPDGYDILFLQGGASLQFSMVPMNFLTEGKIGCYVLTGAWSEKALKEAQKIGLTTV
HHHCCCCCCEEEEEECCCCEEEEEECHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCEEE
VASSKEANYTYIPSLDDVKWPKDASYVHITSNNTIFGTQWNEFPDVPVDLVADMSSDILS
EECCCCCCEEECCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHC
RPFDVSKFALIYAGAQKNLGPSGVTVVIIRNDLLERIPDGLPTMLDYRTHQKSNSLYNTP
CCCCCCEEEEEEECCCCCCCCCCEEEEEEEHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
PTFAIYMLSLVLEWVEEQGGVAAIEARNQQKAAVLYEAIDESGGFYKPHAEKGSRSLMNV
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TFTLPSEELTKAFLAEAKERNFVGLGGHRSVGGCRASIYNAVPLEACEALAAFMNDFRRR
EEECCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
FA
CC
>Mature Secondary Structure 
TVERVYNFNAGPSALPLPVLERAQKELLNFQNTGMSVMELSHRSKEYDAVHNAAKERLK
CCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHH
RLLNVPDGYDILFLQGGASLQFSMVPMNFLTEGKIGCYVLTGAWSEKALKEAQKIGLTTV
HHHCCCCCCEEEEEECCCCEEEEEECHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCEEE
VASSKEANYTYIPSLDDVKWPKDASYVHITSNNTIFGTQWNEFPDVPVDLVADMSSDILS
EECCCCCCEEECCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHC
RPFDVSKFALIYAGAQKNLGPSGVTVVIIRNDLLERIPDGLPTMLDYRTHQKSNSLYNTP
CCCCCCEEEEEEECCCCCCCCCCEEEEEEEHHHHHHCCCCCCHHHHHHHHHCCCCCCCCC
PTFAIYMLSLVLEWVEEQGGVAAIEARNQQKAAVLYEAIDESGGFYKPHAEKGSRSLMNV
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TFTLPSEELTKAFLAEAKERNFVGLGGHRSVGGCRASIYNAVPLEACEALAAFMNDFRRR
EEECCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHH
FA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA