Click here to switch to the map view.

The map label for this gene is coaA [H]

Identifier: 138893742

GI number: 138893742

Start: 75893

End: 76669

Strand: Direct

Name: coaA [H]

Synonym: GTNG_0063

Alternate gene names: 138893742

Gene position: 75893-76669 (Clockwise)

Preceding gene: 138893741

Following gene: 138893743

Centisome position: 2.14

GC content: 46.72

Gene sequence:

>777_bases
ATGATTTTTGTGTTGGACGTTGGCAATACAAATACCGTGCTAGGGGTTTATGACGGTGATGAATTAAAATACCATTGGCG
CATTGAGACAAGCCGGGCGAAAACGGAAGACGAGTACGGCATGACAATTAAAGCGCTTTTGAATCATGTCGGCTTACAGT
TTTCCGATATTCGTGGCATGATTATTTCTTCTGTGGTGCCGCCGATTATGTTTGCCCTTGAACGCATGTGTTTAAAATAT
TTCCATATTAAGCCGCTCATTGTCGGGCCGGGCATTAAAACGGGGCTTGACATTAAATATGAAAATCCGCGTGAAGTCGG
CGCTGACCGGATTGTCAATGCGGTTGCCGGCATTCACTTATACGGCAGCCCACTGATCATTGTCGATTTCGGGACAGCGA
CGACGTATTGTTATATTAATGAACATAAACAATATATGGGGGGAGCTATCGCCCCAGGCATCATGATTTCGACAGAGGCG
TTGTTCGCAAGGGCGGCGAAATTGCCTCGCATTGAAATTGCCCGCCCAGACGATATCGTTGGTAAAAATACGGTCAGCGC
CATGCAAGCTGGCATTTTATACGGTTATGTTGGACAAGTGGAAGGCATCGTTTCGCGAATGAAGGCGAAAAGCAAAGTTC
CACCGAAAGTGATCGCGACTGGTGGCCTTGCACCGCTCATTGCCAGTGAGTCGAGTGTCATCGATGTCGTCGATCCGTTT
TTAACGTTGACTGGGCTGAAACTGTTGTATGAGAAAAATACGGAGAAAAAAGGATGA

Upstream 100 bases:

>100_bases
CTATTGACCGGAGTGAGGCCGCCGTTTTTTCCCCCGCAAGAAAACAAGGTATGATATGATAAAGAAAGGAATTTATTGAG
GAAAAGTGGGGAATGAGGCC

Downstream 100 bases:

>100_bases
AAGGCTTGATGAACATGGGAGATTACTTAGTGAAAGCGCTCGCTTATGATGGACAAGTGAGAGCGTATGCCACAAGAACG
ACAGAAACAGTTGCAGAAGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MIFVLDVGNTNTVLGVYDGDELKYHWRIETSRAKTEDEYGMTIKALLNHVGLQFSDIRGMIISSVVPPIMFALERMCLKY
FHIKPLIVGPGIKTGLDIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEHKQYMGGAIAPGIMISTEA
LFARAAKLPRIEIARPDDIVGKNTVSAMQAGILYGYVGQVEGIVSRMKAKSKVPPKVIATGGLAPLIASESSVIDVVDPF
LTLTGLKLLYEKNTEKKG

Sequences:

>Translated_258_residues
MIFVLDVGNTNTVLGVYDGDELKYHWRIETSRAKTEDEYGMTIKALLNHVGLQFSDIRGMIISSVVPPIMFALERMCLKY
FHIKPLIVGPGIKTGLDIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEHKQYMGGAIAPGIMISTEA
LFARAAKLPRIEIARPDDIVGKNTVSAMQAGILYGYVGQVEGIVSRMKAKSKVPPKVIATGGLAPLIASESSVIDVVDPF
LTLTGLKLLYEKNTEKKG
>Mature_258_residues
MIFVLDVGNTNTVLGVYDGDELKYHWRIETSRAKTEDEYGMTIKALLNHVGLQFSDIRGMIISSVVPPIMFALERMCLKY
FHIKPLIVGPGIKTGLDIKYENPREVGADRIVNAVAGIHLYGSPLIIVDFGTATTYCYINEHKQYMGGAIAPGIMISTEA
LFARAAKLPRIEIARPDDIVGKNTVSAMQAGILYGYVGQVEGIVSRMKAKSKVPPKVIATGGLAPLIASESSVIDVVDPF
LTLTGLKLLYEKNTEKKG

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28146; Mature: 28146

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVLDVGNTNTVLGVYDGDELKYHWRIETSRAKTEDEYGMTIKALLNHVGLQFSDIRGM
CEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCCHHHCEEHHHHHHHHCCEEHHHHHH
IISSVVPPIMFALERMCLKYFHIKPLIVGPGIKTGLDIKYENPREVGADRIVNAVAGIHL
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHCEEE
YGSPLIIVDFGTATTYCYINEHKQYMGGAIAPGIMISTEALFARAAKLPRIEIARPDDIV
ECCCEEEEEECCCEEEEEEECCHHHCCCCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCC
GKNTVSAMQAGILYGYVGQVEGIVSRMKAKSKVPPKVIATGGLAPLIASESSVIDVVDPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCHHHHHHH
LTLTGLKLLYEKNTEKKG
HHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MIFVLDVGNTNTVLGVYDGDELKYHWRIETSRAKTEDEYGMTIKALLNHVGLQFSDIRGM
CEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCCHHHCEEHHHHHHHHCCEEHHHHHH
IISSVVPPIMFALERMCLKYFHIKPLIVGPGIKTGLDIKYENPREVGADRIVNAVAGIHL
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHCEEE
YGSPLIIVDFGTATTYCYINEHKQYMGGAIAPGIMISTEALFARAAKLPRIEIARPDDIV
ECCCEEEEEECCCEEEEEEECCHHHCCCCCCCCEEEEHHHHHHHHHCCCEEEECCCCCCC
GKNTVSAMQAGILYGYVGQVEGIVSRMKAKSKVPPKVIATGGLAPLIASESSVIDVVDPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCHHHHHHH
LTLTGLKLLYEKNTEKKG
HHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA