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The map label for this gene is trpR [H]

Identifier: 134302802

GI number: 134302802

Start: 1895783

End: 1896070

Strand: Reverse

Name: trpR [H]

Synonym: FTW_2026

Alternate gene names: 134302802

Gene position: 1896070-1895783 (Counterclockwise)

Preceding gene: 134302803

Following gene: 134302801

Centisome position: 99.87

GC content: 23.26

Gene sequence:

>288_bases
ATGAATACATTTAATAATGGTTGGCAACAATTAATTAATATTTTATCTGAAAATTCAGACCCACAAGATATAAATATAAT
TTGTGATTTTTTATTAACTAAAGAAGAGAAAGAACAATTAAGTAAAAGAGTACTTCTAACCAAAGAACTTATTAAAAAAT
CTAAATCTCAAAGAGAAATATCTAAAGAAATAGGTATTAGTATTTGTACAGTAACTAGATGTTCGAATGCTTTAAAAGAT
TGTTCTGCAAGGGTAAAAGAAATATTTAGTGAAAATATCAAAAAATAG

Upstream 100 bases:

>100_bases
TCTAAAACAAGTTTATTATAATAATCTTTGTATTTAAATAATTGTTATTTATTTTGTAATGGTATAACATTACAAAAATA
CAAAATGATATATTTTTATT

Downstream 100 bases:

>100_bases
GTGAATAAATGTCAGTTAAAGAACCAGAAAAATTTTTAGCATCACATATTTATAATATAGATTATCAAGAAGATTTAAAT
AAATGCTTTGCTAATTTATG

Product: trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNTFNNGWQQLINILSENSDPQDINIICDFLLTKEEKEQLSKRVLLTKELIKKSKSQREISKEIGISICTVTRCSNALKD
CSARVKEIFSENIKK

Sequences:

>Translated_95_residues
MNTFNNGWQQLINILSENSDPQDINIICDFLLTKEEKEQLSKRVLLTKELIKKSKSQREISKEIGISICTVTRCSNALKD
CSARVKEIFSENIKK
>Mature_95_residues
MNTFNNGWQQLINILSENSDPQDINIICDFLLTKEEKEQLSKRVLLTKELIKKSKSQREISKEIGISICTVTRCSNALKD
CSARVKEIFSENIKK

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription [H]

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family [H]

Homologues:

None

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- ProDom:   PD012582 [H]

Pfam domain/function: PF01371 Trp_repressor [H]

EC number: NA

Molecular weight: Translated: 10932; Mature: 10932

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFNNGWQQLINILSENSDPQDINIICDFLLTKEEKEQLSKRVLLTKELIKKSKSQREI
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKEIGISICTVTRCSNALKDCSARVKEIFSENIKK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTFNNGWQQLINILSENSDPQDINIICDFLLTKEEKEQLSKRVLLTKELIKKSKSQREI
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKEIGISICTVTRCSNALKDCSARVKEIFSENIKK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA