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The map label for this gene is dtd [H]

Identifier: 134302764

GI number: 134302764

Start: 1854014

End: 1854451

Strand: Reverse

Name: dtd [H]

Synonym: FTW_1975

Alternate gene names: 134302764

Gene position: 1854451-1854014 (Counterclockwise)

Preceding gene: 134302765

Following gene: 134302760

Centisome position: 97.68

GC content: 31.05

Gene sequence:

>438_bases
ATGCTTAGTATTATTCAAAGAGTTAATTGTGCAAAGGTGGTAGTTGATAACCAAAAAGTTGCTGATATAAATAAAGGTAT
CTTAGCACTAGTGTGTGTTGAGAAAGAAGATACTCAACAAAACTTTGAAAAAATGGCTGATAAAATCATCAAGTATCGTA
TATTTGAAGATGATGCTGGTAAGATGAATCTATCACTTGTAGATATTGATGCAGAGATAATTCTTGTACCTCAGTTTACT
CTTGCTGCAGATACAAAAAAAGGTAATAGACCAAGTTTTAGCAGTGGTTGTCCCCCAGAAATAGCAAAAGAAAAATTCAA
AGAGTTTGAAAATATTTTTAGAAGAAAATATAACAAAGTACAAACAGGAATATTTGGTGCTGATATGAAAGTATCTTTGA
CAAATGATGGCCCTGTAACATTTAGTTTTAAGATTTAG

Upstream 100 bases:

>100_bases
TAACTATGCTAGTTATATATAAAATCACTATAAGACTTATACTGTATAAGTTATTTTTTGATACAACTCTAAAAATATTT
ATAAATTTTTTAAAAATAGC

Downstream 100 bases:

>100_bases
TAATTAGTAAAAGATAAATGAATTACATCTTATAGAAAAATAAATGCACATTAGCGATTAGTAATTTCAAAAACAAATAA
CTAGGAAATAAAATTGTTTG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLSIIQRVNCAKVVVDNQKVADINKGILALVCVEKEDTQQNFEKMADKIIKYRIFEDDAGKMNLSLVDIDAEIILVPQFT
LAADTKKGNRPSFSSGCPPEIAKEKFKEFENIFRRKYNKVQTGIFGADMKVSLTNDGPVTFSFKI

Sequences:

>Translated_145_residues
MLSIIQRVNCAKVVVDNQKVADINKGILALVCVEKEDTQQNFEKMADKIIKYRIFEDDAGKMNLSLVDIDAEIILVPQFT
LAADTKKGNRPSFSSGCPPEIAKEKFKEFENIFRRKYNKVQTGIFGADMKVSLTNDGPVTFSFKI
>Mature_145_residues
MLSIIQRVNCAKVVVDNQKVADINKGILALVCVEKEDTQQNFEKMADKIIKYRIFEDDAGKMNLSLVDIDAEIILVPQFT
LAADTKKGNRPSFSSGCPPEIAKEKFKEFENIFRRKYNKVQTGIFGADMKVSLTNDGPVTFSFKI

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=38.7755102040816, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=44.1379310344828, Blast_Score=137, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115533292, Length=146, Percent_Identity=34.9315068493151, Blast_Score=89, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=141, Percent_Identity=39.0070921985816, Blast_Score=102, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=36.3013698630137, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16325; Mature: 16325

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIIQRVNCAKVVVDNQKVADINKGILALVCVEKEDTQQNFEKMADKIIKYRIFEDDAG
CCHHHHHCCEEEEEECCCEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEEECCCC
KMNLSLVDIDAEIILVPQFTLAADTKKGNRPSFSSGCPPEIAKEKFKEFENIFRRKYNKV
EEEEEEEECCCEEEEECCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QTGIFGADMKVSLTNDGPVTFSFKI
HCCEECCCEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MLSIIQRVNCAKVVVDNQKVADINKGILALVCVEKEDTQQNFEKMADKIIKYRIFEDDAG
CCHHHHHCCEEEEEECCCEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHEEEEEECCCC
KMNLSLVDIDAEIILVPQFTLAADTKKGNRPSFSSGCPPEIAKEKFKEFENIFRRKYNKV
EEEEEEEECCCEEEEECCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QTGIFGADMKVSLTNDGPVTFSFKI
HCCEECCCEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA