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The map label for this gene is aaeR [H]

Identifier: 134302729

GI number: 134302729

Start: 1811658

End: 1812554

Strand: Reverse

Name: aaeR [H]

Synonym: FTW_1931

Alternate gene names: 134302729

Gene position: 1812554-1811658 (Counterclockwise)

Preceding gene: 134302733

Following gene: 134302728

Centisome position: 95.47

GC content: 30.88

Gene sequence:

>897_bases
ATGAACAAGCATAAAAATATATCAATAAGCCTTTTTGAAGCATTTTATCAACTTGTTGTCCATGGTAGCTTTACTAATAC
AGCGAAAGCTCTAGGGATTTCAAAAGCAGCCGTTAGCCATACTATTAAACAGTTAGAGAAAGAACTAAAAGTAGACTTAC
TTAACAGGACAACACGTTCGCTATCATTAACTCATGAAGGTATGCTTTTATTTAATTATTGTAAAACACTACAAAATGAG
ATTGATAATATTCGTGATTTAGCAGAGTCTTTTCATAAAGAGCCGTCAGGAACTCTAAAAATAAGCACCTCATCATTCTT
TGCACAAAATATTCTTATTAACCTCATCAAAGAATATTCAAAGAAATTTAGCAAGGTTAAAATTGAGGTGAGTATTGAAG
AAAAAATGCCTAACTTCAAATCTAATGAAGCCGATATAATTCTAGGCGTCAATTGGACACCTCCAGAAAACATAGTAGCA
CGTAAAATAGCAACAACAAGATATGTATTATGCGCAAGTCCTGCATATATAAACAAAAATGGCTCACCAAGCAACATATC
AGATCTAGCTAATCATAACTATATTCCTCATAAATCTAGAGTTACTCCACTAGTTAACATCAAGAAAAACAAGCTAAATC
CACAGACTTTACCCTCTAATATCTCAGCCAATAATATTGAGTTTATAAAAGCGTGTGTTTTAAATGATTTTGGCATAGCT
CAATTTCATGAATATATTGTAAAGAACGAAATACAAAACAGTCAACTTATAGAGTTACTAAAAGATAATTTTTTCGATCA
GCAAGATATTTATATTTACTATCCAAAAAATAAATTTGTACAACCAAAAGTGAAAGAGTTTGTGAACTTAGTCATAAATA
GCCAAATTTCTATCTAG

Upstream 100 bases:

>100_bases
TTAATCCTCTTCATAAAAATTTAACTATGAGATATGGTAAATTAAAAAATATATTTTACAATATCACCATATATTGACAT
AAGTTTAGATTTATTTGACA

Downstream 100 bases:

>100_bases
TGGTATAATAGCTTTATATCTTTTATCTTATCAATTATTATTATAATAGTTTCCTAACAGAATAATAGTTATGAGTCACA
AGTAACATTAAAATTAATCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNKHKNISISLFEAFYQLVVHGSFTNTAKALGISKAAVSHTIKQLEKELKVDLLNRTTRSLSLTHEGMLLFNYCKTLQNE
IDNIRDLAESFHKEPSGTLKISTSSFFAQNILINLIKEYSKKFSKVKIEVSIEEKMPNFKSNEADIILGVNWTPPENIVA
RKIATTRYVLCASPAYINKNGSPSNISDLANHNYIPHKSRVTPLVNIKKNKLNPQTLPSNISANNIEFIKACVLNDFGIA
QFHEYIVKNEIQNSQLIELLKDNFFDQQDIYIYYPKNKFVQPKVKEFVNLVINSQISI

Sequences:

>Translated_298_residues
MNKHKNISISLFEAFYQLVVHGSFTNTAKALGISKAAVSHTIKQLEKELKVDLLNRTTRSLSLTHEGMLLFNYCKTLQNE
IDNIRDLAESFHKEPSGTLKISTSSFFAQNILINLIKEYSKKFSKVKIEVSIEEKMPNFKSNEADIILGVNWTPPENIVA
RKIATTRYVLCASPAYINKNGSPSNISDLANHNYIPHKSRVTPLVNIKKNKLNPQTLPSNISANNIEFIKACVLNDFGIA
QFHEYIVKNEIQNSQLIELLKDNFFDQQDIYIYYPKNKFVQPKVKEFVNLVINSQISI
>Mature_298_residues
MNKHKNISISLFEAFYQLVVHGSFTNTAKALGISKAAVSHTIKQLEKELKVDLLNRTTRSLSLTHEGMLLFNYCKTLQNE
IDNIRDLAESFHKEPSGTLKISTSSFFAQNILINLIKEYSKKFSKVKIEVSIEEKMPNFKSNEADIILGVNWTPPENIVA
RKIATTRYVLCASPAYINKNGSPSNISDLANHNYIPHKSRVTPLVNIKKNKLNPQTLPSNISANNIEFIKACVLNDFGIA
QFHEYIVKNEIQNSQLIELLKDNFFDQQDIYIYYPKNKFVQPKVKEFVNLVINSQISI

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=296, Percent_Identity=27.027027027027, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=27.5618374558304, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=25.2559726962457, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87081978, Length=279, Percent_Identity=26.1648745519713, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI145693193, Length=276, Percent_Identity=25.3623188405797, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=22.7586206896552, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=21.4035087719298, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788706, Length=292, Percent_Identity=22.2602739726027, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082132, Length=291, Percent_Identity=23.0240549828179, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=279, Percent_Identity=23.6559139784946, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33951; Mature: 33951

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHKNISISLFEAFYQLVVHGSFTNTAKALGISKAAVSHTIKQLEKELKVDLLNRTTRS
CCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLTHEGMLLFNYCKTLQNEIDNIRDLAESFHKEPSGTLKISTSSFFAQNILINLIKEYS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
KKFSKVKIEVSIEEKMPNFKSNEADIILGVNWTPPENIVARKIATTRYVLCASPAYINKN
HHHHEEEEEEEEHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHEEEEECCCCEECCC
GSPSNISDLANHNYIPHKSRVTPLVNIKKNKLNPQTLPSNISANNIEFIKACVLNDFGIA
CCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
QFHEYIVKNEIQNSQLIELLKDNFFDQQDIYIYYPKNKFVQPKVKEFVNLVINSQISI
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKHKNISISLFEAFYQLVVHGSFTNTAKALGISKAAVSHTIKQLEKELKVDLLNRTTRS
CCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLTHEGMLLFNYCKTLQNEIDNIRDLAESFHKEPSGTLKISTSSFFAQNILINLIKEYS
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
KKFSKVKIEVSIEEKMPNFKSNEADIILGVNWTPPENIVARKIATTRYVLCASPAYINKN
HHHHEEEEEEEEHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHEEEEECCCCEECCC
GSPSNISDLANHNYIPHKSRVTPLVNIKKNKLNPQTLPSNISANNIEFIKACVLNDFGIA
CCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHH
QFHEYIVKNEIQNSQLIELLKDNFFDQQDIYIYYPKNKFVQPKVKEFVNLVINSQISI
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]