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The map label for this gene is dnaX [H]

Identifier: 134302702

GI number: 134302702

Start: 1783944

End: 1785584

Strand: Direct

Name: dnaX [H]

Synonym: FTW_1901

Alternate gene names: 134302702

Gene position: 1783944-1785584 (Clockwise)

Preceding gene: 134302699

Following gene: 134302709

Centisome position: 93.97

GC content: 32.78

Gene sequence:

>1641_bases
ATGTCATATCAAGCATTAGCAAGAAAATATCGTCCACAATCATTCGCAGAAGTTGCTGGACAACAACATGCTCTTAACAG
TTTAGTACATGCTTTAGAAACTCAAAAAGTTCACCATGCCTACTTATTTACGGGTACGCGTGGGGTTGGTAAGACAACAC
TTGGTAGACTCTTAGCAAAATGTCTAAATTGTAAAACTGGTGTTACTGCTGAGCCTTGCAACAAATGTGAAAACTGTGTA
GCAATCAATAATAACAGCTTTATAGATTTGATCGAGATTGATGCTGCTTCACGTACAGGTGTTGAAGAGACTAAAGAAAT
CTTAGATAATATCCAATATATGCCTTCACAAGGACGCTATAAAGTCTATCTAATCGATGAGGTACATATGCTATCTAAGC
AAAGTTTCAATGCTTTGCTAAAGACTCTCGAAGAGCCACCAGAATATGTCAAATTTATCCTAGCTACAACAGATTATCAC
AAAATCCCTGTTACGATACTTTCTAGATGTATCCAACTTCATCTCAAACATATCTCACAAGCTGATATCAAAGATCAACT
AAAAATAATTCTAGCTAAAGAGAATATAAATTCAGATGAGCAATCACTTGAATACATAGCTTATCATGCTAAAGGCAGTT
TAAGAGATGCTTTAAGCTTACTTGATCAGGCTATTAGCTTTTGTGGTGGTGAACTTAAGCAAGCTCAGATCAAACAAATG
CTTGGAATTATCGATAGTGAAGAAGTATATAGTATTATCAATGCAATTATTGATAATGATCCAAAAGCTATATTGCCAGC
CATCAAAAATTTAGCACTTACAGAAAGTAGTGCTGATGCTGTACTAGATAGAATTGCTGAAATTTGGTTCGCTTGCTGTA
TATATAGCTTTACCCAATCACTAGATGCTGTTAATGATATTGATGTTGATATAATCAATAATATTTTGGCAAAAATATCA
ATCGAACAAGCACATTTTTTGTATCAACTAACGATAACCGCCAAAAAAGATATTGCTTTAGCACCAAATTTCGAAACTGG
TGTAACTATGGCTATACTTAGACTTATAGCGTTTCAAAAAAAAAATCTAATTGATAAAACCCAAACCTCTAAGTCAAATA
TTAGCCCAATAGTTTCTAAAAATGATATAAATCTGCTTAAAAACACATTTAAGTCAGAACAACCTAAACAGACTGTAAAA
GCTGTTGTAGCACAAAATAATGATTCAACAGCTAGTGAAAATACTCAAGAACAATCATTAGATAAAAAATGGTTTAATCT
GCTTAATAGAATAAAACTGAAAGGCTTCACAAAAACGCTCGCTTTTAATAGTCACCTTATTAGTGATAATAGTGAAACAT
TTGTAATCCATCTAAATGAAGATGCCAAAAAAATCCTTGAGCTTGATCCTCAAAGCATAGCTAAACTTCAAGCAAGTATT
AGTGAGTATCTTAACAACCCTAGTTTTAGGTTAGATATCAAAAACCTAGCTATGGATAAAGTCTCAACTGATCAAAAGTC
TCCTGCTGAAATTAAGCGTGAAAATGCTATAAGTAAAATTCATAATGATGAGAATACAAAGCTTATTAAACAAGCTCTCG
CAATTGATATAAAGGATCAAAATATAATTTTAACAGATTAG

Upstream 100 bases:

>100_bases
ACAAACAAAGACTATTGAAAGTTATCTAAATACCCTCTTATTCTTTTAGCCTAACTCTGTTATTATTTAATATAAGATTT
TCTAATAGATTAATTTGTAA

Downstream 100 bases:

>100_bases
AAGTTTAAAAAACCTAAATGTATTCCCACGCATCTTTATCAGCAAAGACAGCATGTAGAAGTTTGTTATTAAGAGTATGT
CCAGACTTAAAACAGTTGAA

Product: DNA polymerase III, gamma/tau subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV
AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH
KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM
LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVNDIDVDIINNILAKIS
IEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQKKNLIDKTQTSKSNISPIVSKNDINLLKNTFKSEQPKQTVK
AVVAQNNDSTASENTQEQSLDKKWFNLLNRIKLKGFTKTLAFNSHLISDNSETFVIHLNEDAKKILELDPQSIAKLQASI
SEYLNNPSFRLDIKNLAMDKVSTDQKSPAEIKRENAISKIHNDENTKLIKQALAIDIKDQNIILTD

Sequences:

>Translated_546_residues
MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCV
AINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH
KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM
LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVNDIDVDIINNILAKIS
IEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQKKNLIDKTQTSKSNISPIVSKNDINLLKNTFKSEQPKQTVK
AVVAQNNDSTASENTQEQSLDKKWFNLLNRIKLKGFTKTLAFNSHLISDNSETFVIHLNEDAKKILELDPQSIAKLQASI
SEYLNNPSFRLDIKNLAMDKVSTDQKSPAEIKRENAISKIHNDENTKLIKQALAIDIKDQNIILTD
>Mature_545_residues
SYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVA
INNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHK
IPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQML
GIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVNDIDVDIINNILAKISI
EQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQKKNLIDKTQTSKSNISPIVSKNDINLLKNTFKSEQPKQTVKA
VVAQNNDSTASENTQEQSLDKKWFNLLNRIKLKGFTKTLAFNSHLISDNSETFVIHLNEDAKKILELDPQSIAKLQASIS
EYLNNPSFRLDIKNLAMDKVSTDQKSPAEIKRENAISKIHNDENTKLIKQALAIDIKDQNIILTD

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=258, Percent_Identity=24.031007751938, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI31881687, Length=258, Percent_Identity=24.031007751938, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1786676, Length=378, Percent_Identity=45.5026455026455, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1787119, Length=233, Percent_Identity=27.4678111587983, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322528, Length=306, Percent_Identity=22.8758169934641, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=286, Percent_Identity=21.6783216783217, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647857, Length=221, Percent_Identity=25.3393665158371, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 61132; Mature: 61001

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAK
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHH
CLNCKTGVTAEPCNKCENCVAINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRY
HHCCCCCCCCCHHHHCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLKHISQ
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
ADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM
CCHHHHHEEEEEECCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQS
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDAVNDIDVDIINNILAKISIEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQK
HCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHH
KNLIDKTQTSKSNISPIVSKNDINLLKNTFKSEQPKQTVKAVVAQNNDSTASENTQEQSL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHH
DKKWFNLLNRIKLKGFTKTLAFNSHLISDNSETFVIHLNEDAKKILELDPQSIAKLQASI
HHHHHHHHHHHHHCCHHHHHEECCEEECCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHH
SEYLNNPSFRLDIKNLAMDKVSTDQKSPAEIKRENAISKIHNDENTKLIKQALAIDIKDQ
HHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCC
NIILTD
EEEECC
>Mature Secondary Structure 
SYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHH
CLNCKTGVTAEPCNKCENCVAINNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRY
HHCCCCCCCCCHHHHCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCIQLHLKHISQ
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHH
ADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM
CCHHHHHEEEEEECCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQS
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LDAVNDIDVDIINNILAKISIEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFQK
HCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHH
KNLIDKTQTSKSNISPIVSKNDINLLKNTFKSEQPKQTVKAVVAQNNDSTASENTQEQSL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHH
DKKWFNLLNRIKLKGFTKTLAFNSHLISDNSETFVIHLNEDAKKILELDPQSIAKLQASI
HHHHHHHHHHHHHCCHHHHHEECCEEECCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHH
SEYLNNPSFRLDIKNLAMDKVSTDQKSPAEIKRENAISKIHNDENTKLIKQALAIDIKDQ
HHHHCCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCC
NIILTD
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]