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The map label for this gene is lpxP [H]

Identifier: 134302669

GI number: 134302669

Start: 1743042

End: 1743941

Strand: Direct

Name: lpxP [H]

Synonym: FTW_1857

Alternate gene names: 134302669

Gene position: 1743042-1743941 (Clockwise)

Preceding gene: 134302668

Following gene: 134302670

Centisome position: 91.81

GC content: 32.78

Gene sequence:

>900_bases
ATGGATAAATCTCTACTTAAACCAAAATATTGGGGTATATGGATTATAATTTGGATCGCCAAGTTTATAGTAAATATACT
TCCATACAAAATGCTAATGCGTCTTGCAATAGACATTGGTTTTTTAGCAAAGCCTCTACTCAAAAAACGTCAACAAATAG
CAATTACCAATCTTAAGATCGCATTCCCTGAAAAATCAGATCAAGAAATAAAAAAACTAGCCGATGCTAGTTATAAATCA
GCTAGTATGGCTGGTTTTGAAAGTCTAATTTCTTGGTTCATGACTAAAAAGAACTTCAACAAAATTCCTTTTGATAACGA
TCTAAGATCATTTGATGAAATTCATTATGACAAAGACAAAACTCTACTAGTATTAGGTTTTCACTTTCATTGCCTTGAGA
TAGCTGGTCGCTATATTGGTGAGAACTATAGTCCGTTTACAGTAATGTATCAATACCATAATAATCCTCTGATGGAATAT
ATCATTACCTCATCACGCAAAAAGTATGTGACTGAATGCTTCCAAAGAAAAAATATAATCGCCGTTATCAAAAGTTTAAA
AAGAAAAGTCTCTATGTGGTATGCTCCAGATCAAGACTTTAGAGAACATGTAGTTTTTGCACCATTCTTTGGTAAGCTTT
GTACTACCCTAACCGTAACACCATGGTTAGCAGAAAAAACAAATGCTACTGTTATTCCAGCTTACTATGTCAGAAAGCCC
GATCTTTCCGGATATAGTATTATAACTGGAGAGCCAATAATATTTAGTGGTAATGATCTAGAAGATGCGAAACTAACAAA
TAAAATCCTTGAAGAAATAATTAAAAAACATCCTGAACAATATTTATGGCAGCATCGTCGCTATAAAACAAGACCACTAG
GTGAAGAAAAAATTTATTAG

Upstream 100 bases:

>100_bases
TGGTCTAGTATTATATTGGCTGACGAATAACCTAATCAGTATTTCACAACAGTGGATTATTACAAGACACTATCAAGCCA
CTCATAAAAAATAAATATAC

Downstream 100 bases:

>100_bases
TATTTATGATTGTTAAAGTATATGTTAAAATGTCAATAGCGTTTTAATGTTAAGAAGTAAATGAATAATAACAAGTTTAG
TCCTAAAAACTGGGGTATCT

Product: putative lipid A biosynthesis acyltransferase

Products: KDO2-(palmitoleoyl)-lipid IVA [C]

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIDIGFLAKPLLKKRQQIAITNLKIAFPEKSDQEIKKLADASYKS
ASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDKTLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEY
IITSSRKKYVTECFQRKNIIAVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY

Sequences:

>Translated_299_residues
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIDIGFLAKPLLKKRQQIAITNLKIAFPEKSDQEIKKLADASYKS
ASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDKTLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEY
IITSSRKKYVTECFQRKNIIAVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY
>Mature_299_residues
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIDIGFLAKPLLKKRQQIAITNLKIAFPEKSDQEIKKLADASYKS
ASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDKTLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEY
IITSSRKKYVTECFQRKNIIAVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=305, Percent_Identity=35.7377049180328, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1787292, Length=302, Percent_Identity=34.1059602649007, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1788161, Length=303, Percent_Identity=24.4224422442244, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: NA

Molecular weight: Translated: 35191; Mature: 35191

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIDIGFLAKPLLKKRQQIAITNLKI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
AFPEKSDQEIKKLADASYKSASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDK
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
TLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEYIITSSRKKYVTECFQRKNII
EEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHCCCHH
AVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
HHHHHHHHHHHHCCCCCHHHHHHEEECHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEECC
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY
CCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDKSLLKPKYWGIWIIIWIAKFIVNILPYKMLMRLAIDIGFLAKPLLKKRQQIAITNLKI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEE
AFPEKSDQEIKKLADASYKSASMAGFESLISWFMTKKNFNKIPFDNDLRSFDEIHYDKDK
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
TLLVLGFHFHCLEIAGRYIGENYSPFTVMYQYHNNPLMEYIITSSRKKYVTECFQRKNII
EEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHCCCHH
AVIKSLKRKVSMWYAPDQDFREHVVFAPFFGKLCTTLTVTPWLAEKTNATVIPAYYVRKP
HHHHHHHHHHHHCCCCCHHHHHHEEECHHHHHHHHHHCCCCHHHCCCCCEEEEEEEEECC
DLSGYSIITGEPIIFSGNDLEDAKLTNKILEEIIKKHPEQYLWQHRRYKTRPLGEEKIY
CCCCEEEEECCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; palmitoleoyl-ACP [C]

Specific reaction: KDO2-lipid IVA + palmitoleoyl-ACP = KDO2-(palmitoleoyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]