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The map label for this gene is lolC [H]

Identifier: 134302513

GI number: 134302513

Start: 1581843

End: 1583105

Strand: Reverse

Name: lolC [H]

Synonym: FTW_1669

Alternate gene names: 134302513

Gene position: 1583105-1581843 (Counterclockwise)

Preceding gene: 134302514

Following gene: 134302512

Centisome position: 83.39

GC content: 35.08

Gene sequence:

>1263_bases
ATGTTTAAAAGCTTACCACTATTTATCGGATTAAGATATATCCGTGCTAAGAAGCGTAACCGGTTTATATCTATTATATC
GGCAATATCATTTTTGGGTATTTCTCTAGGTGTGGCTGTACTTATCACAGTGATGTCGGTTATGAATGGGTTTGATCAGC
AGATCAAAAGCAAAATTCTAATGATGGTACCACCTTTAAAAGTGTATCAATTAGGTGGGGAAGTTACTGATTGGCCAAAC
TTAGCTAAAGAAGTTGAGAAAAGTACTCCAAGTGTTACTGCAGTAGCTCCGATAGTAGAATCACAAGGTTTACTTAGTGC
AAATAGTGGTAGTAGCACGACAGCATTTGTACAAATTCAGGGTATAGAACCTAAGTATCAAACCAAAGTACTACCTATAG
CTGAGCATATTGTCGATGGTAAGCTGTCATCGTTAGATGATAATCAAGGTTATAATATAGTTTTAGGTAGTGTCTTGGCT
GATAATTTAGGTGTTAAAGTTGGTGATAAGGTGACTTTAATCGTACCAAAGATTAGTCTAACGCCGGCTGGGATGATCCC
AAGAATTAAGCAGTTTAGAGTGTCTGGAATATTCTCTGTGAGCTATCAATATGATGCTTATTATGCGATGATTAATATTA
AGGATGCACAAAAAGTTTTTGAGACGGGTAATTCAGTATCATCTCTTCAACTAAGTGTAAAAAATATCTATGATGCACCA
CTTGTTAAAGACAAACTCAATGATGGTACCATTCCTCCTTACTATTTCACTCGTGATTGGACGGATGAGAATAAATCTTT
CTTTGACGCCTTAAAAATGGAAAAAACGATGATGTTTTTTATCCTATTACTAATAATTACTGTCGCTGTATTTAACTTAT
TATCATCTTTAGTTATGGTTGTCACTGATAAGCGTAGTGATATAGCTATTCTTAGAACTATGGGGATGTCATCGCGACAA
ATTATAACGGTATTTATATACCAAGGTTTTATTATTGGTTTGATAGGTACAGTTATTGGTGTATTGCTTGGTATACTTCT
TTCAACTTATGCCACAGAGATAGTTAATTTTATCCAGAATCTTACTGGTAAGCAATTTTTGAGCGCAAGTGTTTATCTTA
TAAATTATATCCCATCGGAGCTTATGTGGTCAGACGTTATAAAAGTTACTTTGGTTTCTATGTTTTTAAGTTTCTTAGCG
ACACTTTATCCTGCTTGGAGTGCTTCTAAGGTTCAGCCAGTGGAGGCTTTAAGATATGAATGA

Upstream 100 bases:

>100_bases
TCACATCAGTTACGATGATTTAGTTAGATGTTTTTGAAATGTTTTTTCATAGCTTAATATGTTATTCTATAGGGTAATTT
TTATTGCAAGAAAAAATTTA

Downstream 100 bases:

>100_bases
TGTTGTTTTAAGTTGCAAAAATGTTTCAAAAAAATATACAGAATTTAAAACTGATATAGCTATCTTAAAAGATGTAAACC
TCGAGATTAAAAAAGGTGAA

Product: LolC/E family lipoprotein releasing system ABC transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKILMMVPPLKVYQLGGEVTDWPN
LAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLA
DNLGVKVGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSVSSLQLSVKNIYDAP
LVKDKLNDGTIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMVVTDKRSDIAILRTMGMSSRQ
IITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLA
TLYPAWSASKVQPVEALRYE

Sequences:

>Translated_420_residues
MFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKILMMVPPLKVYQLGGEVTDWPN
LAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLA
DNLGVKVGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSVSSLQLSVKNIYDAP
LVKDKLNDGTIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMVVTDKRSDIAILRTMGMSSRQ
IITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLA
TLYPAWSASKVQPVEALRYE
>Mature_420_residues
MFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKILMMVPPLKVYQLGGEVTDWPN
LAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQGIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLA
DNLGVKVGDKVTLIVPKISLTPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSVSSLQLSVKNIYDAP
LVKDKLNDGTIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMVVTDKRSDIAILRTMGMSSRQ
IITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQNLTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLA
TLYPAWSASKVQPVEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=419, Percent_Identity=35.0835322195704, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI1787360, Length=423, Percent_Identity=35.2245862884161, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46494; Mature: 46494

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
MMVPPLKVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQ
HCCCCHHHEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCEECCCCCCEEEEEEEE
GIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLADNLGVKVGDKVTLIVPKISL
CCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHCCCCCEECCEEEEEEECEEC
TPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSVSSLQLSVKNIYDAP
CCCCCCHHHHHHHHHEEEEEEEEECEEEEEEEEHHHHHHHHCCCCHHHHEEEHHHHCCCC
LVKDKLNDGTIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMV
CHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTDKRSDIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQN
HCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLATLYPAWSASKVQPVEALRYE
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MFKSLPLFIGLRYIRAKKRNRFISIISAISFLGISLGVAVLITVMSVMNGFDQQIKSKIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
MMVPPLKVYQLGGEVTDWPNLAKEVEKSTPSVTAVAPIVESQGLLSANSGSSTTAFVQIQ
HCCCCHHHEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCEECCCCCCEEEEEEEE
GIEPKYQTKVLPIAEHIVDGKLSSLDDNQGYNIVLGSVLADNLGVKVGDKVTLIVPKISL
CCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHCCCCCEECCEEEEEEECEEC
TPAGMIPRIKQFRVSGIFSVSYQYDAYYAMINIKDAQKVFETGNSVSSLQLSVKNIYDAP
CCCCCCHHHHHHHHHEEEEEEEEECEEEEEEEEHHHHHHHHCCCCHHHHEEEHHHHCCCC
LVKDKLNDGTIPPYYFTRDWTDENKSFFDALKMEKTMMFFILLLIITVAVFNLLSSLVMV
CHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTDKRSDIAILRTMGMSSRQIITVFIYQGFIIGLIGTVIGVLLGILLSTYATEIVNFIQN
HCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGKQFLSASVYLINYIPSELMWSDVIKVTLVSMFLSFLATLYPAWSASKVQPVEALRYE
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]