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The map label for this gene is pgm [H]

Identifier: 134302503

GI number: 134302503

Start: 1566312

End: 1567946

Strand: Reverse

Name: pgm [H]

Synonym: FTW_1659

Alternate gene names: 134302503

Gene position: 1567946-1566312 (Counterclockwise)

Preceding gene: 134302507

Following gene: 134302502

Centisome position: 82.59

GC content: 36.02

Gene sequence:

>1635_bases
ATGGCGATTCAAACTGTATCAACTAAACCTTTTGCTAATCAAAAACCAGGTACATCTGGATTACGAAATAAAGTCATAGC
TTTTCAACAGCCCAGATATTTGGAGAACTTTGTACAATCTATATTTAACTCATTGGATGATATAGAAGGTAAAACTTTAG
TTGTTGGTGGTGATGGTAGATATTACAATGATGTTGCAATACAAATTATCGTCAGAATGGCAGCAGCTAATGGTTTTGCT
AAGATAATAGTTGGTCAAAATGGTATATTTTCTACTCCAGCTGTTAGTTGTGTTATCCGAAAATATGAGGCTTTTGGTGG
GATTGTATTATCGGCAAGTCATAATCCGGGTGGTCCAAAAGGAGACTTTGGTATCAAATATAATGTTTCTAATGGTGGTC
CAGCTCCTGAAAAAATTACAGATAGAATTTTTTCTGAAACAAAAAAAATTAATCAATACTTTATAAGTGATGCAGCTAAG
GAAAGTGTTGATCTAGACAAGTTAGGCACATACAAGATTGAGAATACAACTGTCGAGGTTATCAATTCGGTAATTGATTA
TGCTGAGTTGATGCAACAGATTTTTGATTTTGATAAGGTTCGCGAATTATTTGCTAAAGGATTTAAAGTACGTTTTGATT
CTATGTGTGCGGTGTCTGGTCCTTATGCAAAATATATTTTTGAAACTCTTTTGAAAGCTCCAGCAGGCACAGTTGTAAAT
GCTCAGCCACTTGAGGATTTTGGAGGGTTTCATCCAGATCCAAATCCTGTAAATGCTGAAGATTTAGTCAAGCATATGCG
TAGTGGTAAGTATGATTTCGGCGCAGCTTCAGATGGTGATGCTGATAGAAATATGATTGTTGGTAAACAAATAGATGTAT
CTCCTTCAGATAGCCTAGCAATTATGGCTGCAAATGCGCATCTTATACCAGTGTATTCAAAAGGAATTAAAGGTGTTGCT
AGATCGATGCCTACATCAACAGCGGTTGATAGAGTTGCAGAGTCATTACGACTACCTTGTTTCGAGACTCCAACAGGATG
GAAATTCTTTGGTAATTTACTAGATGCTGAAAAAATCACACTATGTGGCGAAGAGAGTTATGGTACCGGCTCTAACCATA
TTCGTGAGAAAGATGGCGTTTGGGCTGTGCTGTTTTGGTTAAATTTAGTTGCAGTTACAGGCAAACAAGTTGATCAACTT
GTTGAAGAACATTGGCAAAAATTTGGGCGTAACTTCTATTCAAGACATGACTATGAGGCTATAGATACTGCGATTGCTAA
CTCTATTATAGACTCTTTAAGAGAAAGGTTGTCTAGTCTAGTAGGAGCTCAGTTGAATGATGAGAAAGTCGCTAAAGCAG
ATGATTTTAGTTATATAGATCCAATAGATGGTTTAGTTTCTAATCATCAAGGAATAAGAATTATTTTTGAAGATGGTTCA
CGTATTGTGTTTAGGTTATCTGGTACAGGAACACAAGGTGCTACTTTACGTATATATTTAGAAAAATATGAGTCAGATTC
TTCTAAGTTTAGTATACCGACACAACAAGCTCTAGCTAGCTTGATAGAGATTGCTGAAGATTTGACCAATATCAAATCTT
TAACAGGAATGACTGAACCAACTGTAGTTACTTAA

Upstream 100 bases:

>100_bases
GATAAGATGAATGATATGGGCTTTTAACCAATAAGCCACCTAACATCGACTAGGCTCACTATTTGGGTGTATGTTAATCA
ATAAATACTAGGGTAAAAAA

Downstream 100 bases:

>100_bases
CTAAAATTTTTTTAACACAAAGGAGCTTATGATATGGATAATCATAATTCATCACATCAGTTGTACAAAAAAGCTATGGC
ATTAGTTTTAGCTGGAGGAC

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MAIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGRYYNDVAIQIIVRMAAANGFA
KIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPKGDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAK
ESVDLDKLGTYKIENTTVEVINSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIDVSPSDSLAIMAANAHLIPVYSKGIKGVA
RSMPTSTAVDRVAESLRLPCFETPTGWKFFGNLLDAEKITLCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQL
VEEHWQKFGRNFYSRHDYEAIDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGLVSNHQGIRIIFEDGS
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEPTVVT

Sequences:

>Translated_544_residues
MAIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGRYYNDVAIQIIVRMAAANGFA
KIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPKGDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAK
ESVDLDKLGTYKIENTTVEVINSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIDVSPSDSLAIMAANAHLIPVYSKGIKGVA
RSMPTSTAVDRVAESLRLPCFETPTGWKFFGNLLDAEKITLCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQL
VEEHWQKFGRNFYSRHDYEAIDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGLVSNHQGIRIIFEDGS
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEPTVVT
>Mature_543_residues
AIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGRYYNDVAIQIIVRMAAANGFAK
IIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPKGDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAKE
SVDLDKLGTYKIENTTVEVINSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVNA
QPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIDVSPSDSLAIMAANAHLIPVYSKGIKGVAR
SMPTSTAVDRVAESLRLPCFETPTGWKFFGNLLDAEKITLCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQLV
EEHWQKFGRNFYSRHDYEAIDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGLVSNHQGIRIIFEDGSR
IVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEPTVVT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=563, Percent_Identity=54.7069271758437, Blast_Score=616, Evalue=1e-176,
Organism=Homo sapiens, GI21361621, Length=561, Percent_Identity=54.0106951871658, Blast_Score=604, Evalue=1e-173,
Organism=Homo sapiens, GI133922562, Length=564, Percent_Identity=48.0496453900709, Blast_Score=539, Evalue=1e-153,
Organism=Homo sapiens, GI290463104, Length=365, Percent_Identity=53.1506849315069, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI239741729, Length=135, Percent_Identity=50.3703703703704, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI239743670, Length=135, Percent_Identity=48.1481481481481, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1786904, Length=429, Percent_Identity=28.6713286713287, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535441, Length=568, Percent_Identity=49.2957746478873, Blast_Score=546, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6323752, Length=567, Percent_Identity=48.6772486772487, Blast_Score=516, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6322722, Length=571, Percent_Identity=45.8844133099825, Blast_Score=479, Evalue=1e-136,
Organism=Drosophila melanogaster, GI17864244, Length=562, Percent_Identity=48.7544483985765, Blast_Score=544, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59636; Mature: 59505

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGR
CCCCCCCCCCCCCCCCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
YYNDVAIQIIVRMAAANGFAKIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPK
EEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
GDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAKESVDLDKLGTYKIENTTVEV
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECCHHHHH
INSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEEC
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIDVSPSDSLA
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEECCCCCCCEE
IMAANAHLIPVYSKGIKGVARSMPTSTAVDRVAESLRLPCFETPTGWKFFGNLLDAEKIT
EEEECCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEE
LCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQLVEEHWQKFGRNFYSRHDYEA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGLVSNHQGIRIIFEDGS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHCCCCCEEEEEECCC
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEP
EEEEEEECCCCCCCEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TVVT
CCCC
>Mature Secondary Structure 
AIQTVSTKPFANQKPGTSGLRNKVIAFQQPRYLENFVQSIFNSLDDIEGKTLVVGGDGR
CCCCCCCCCCCCCCCCCCHHHHCCEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
YYNDVAIQIIVRMAAANGFAKIIVGQNGIFSTPAVSCVIRKYEAFGGIVLSASHNPGGPK
EEHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
GDFGIKYNVSNGGPAPEKITDRIFSETKKINQYFISDAAKESVDLDKLGTYKIENTTVEV
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECCHHHHH
INSVIDYAELMQQIFDFDKVRELFAKGFKVRFDSMCAVSGPYAKYIFETLLKAPAGTVVN
HHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCEEC
AQPLEDFGGFHPDPNPVNAEDLVKHMRSGKYDFGAASDGDADRNMIVGKQIDVSPSDSLA
CCCHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCEECCCCCCCEE
IMAANAHLIPVYSKGIKGVARSMPTSTAVDRVAESLRLPCFETPTGWKFFGNLLDAEKIT
EEEECCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEE
LCGEESYGTGSNHIREKDGVWAVLFWLNLVAVTGKQVDQLVEEHWQKFGRNFYSRHDYEA
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IDTAIANSIIDSLRERLSSLVGAQLNDEKVAKADDFSYIDPIDGLVSNHQGIRIIFEDGS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCHHHHHCCCCCEEEEEECCC
RIVFRLSGTGTQGATLRIYLEKYESDSSKFSIPTQQALASLIEIAEDLTNIKSLTGMTEP
EEEEEEECCCCCCCEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
TVVT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]