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The map label for this gene is ftsW [H]

Identifier: 134302470

GI number: 134302470

Start: 1521798

End: 1523003

Strand: Reverse

Name: ftsW [H]

Synonym: FTW_1618

Alternate gene names: 134302470

Gene position: 1523003-1521798 (Counterclockwise)

Preceding gene: 134302471

Following gene: 134302468

Centisome position: 80.22

GC content: 34.16

Gene sequence:

>1206_bases
GTGTTATATAGATTAAAACTATTGTTGAGTGGCAAAAACTCAAAAAAAGAACGTGTAAGAGCCAAATTAGAGATTGATAT
TTCAATTGTCTTTATAATGCTTGGCCTACTTACTTTTGGTTGGGTTATGGTGACTTCTGCATCTATGATTGTTGCTTTAG
ATGACTACAATAATCCTTATTTTTATTCTATCAGACAGGGTTTTTTTGCAATTATTGCAATTTTTTTATTTTTATTGGCT
TTATTAGTACCAACTAAGAATTATGAAAAGAATTATAATGCTTTTTTCTTTGTGATGTTGATCGTCTTAGTTGCTGTACT
TGTGCCAGGAATTGGGAAAAGTGTCAATGGTGCGCGACGCTGGATACCTTTGCTAATTATTAATATCCAAGTTGCAGAAT
TGGCTAAACTTTTGGCGATTATATTCTTCTCAGGTTATATTGCTGAAAATCTAAAAAAGATGGCTAATTTTAAAGAAGGA
ATTCTTAGACCAATTACTTTATTGGGTTGTATCGCAATATTGTTATTAATGCAGCCAGATTTTGGTTCTACAGTTGTTAT
ATCAATATGTGTTATGGGAATGCTGTTTGTAGCAGGTAACAAAGTGCGCTGGTATGGTTTACTTTTAGGTACTATGGTTA
TGATGGCTGCGATGCTAGTAATTATATCACCATATCGAATGCACAGAATTACAGGGTTTTTACACCCATGGGAAAATGCC
AATGGCTCTGGCTATCAGCTTGTTCAAGCATTGATAGGTTTTGGACGTGGTGGCTGGTTCGGTGATGGTCTCGGGAATGG
AATTCAAAAGCAATTTTTCTTACCAGAAGCACGTACTGACTTTATTACTTCTGTGATTGCTGAGGAATTAGGAGTTGTTG
GTTTGATGGTTCTACTTGCAGTGTACCTTTTTATTGTATTTAGAGCTATGAGTATTGCTAAAATGGCTTTTGAACTTAAT
AGATATTATCAGGCTTTTCTTGCTTATGGTGTTGGTTTTTGGATTGCTTTTCAAGTTTTTGTTAATATTGGTGTTAATAC
AGGACTACTCCCTACTAAGGGTCTTACATTACCACTGATAAGTTATGGGGGAAGTAGTTTATTAATTATGTGTTATACGC
TAGGTGTCTTGGTTAGAGTTGACTTTGAAAACAAACTTTTAGCAGATACCATTAATCCTCGTTATATTTATAAGAAAGTA
AAATAG

Upstream 100 bases:

>100_bases
AGCATGTGCAAGCTTTGATGAATTTAGTGGTTATGCACAGCGCGGTGAAGTTTTTCAAAATCTTGTTGCTCAGCTAGAGC
AAAAAAGTTAGGAAGTATAA

Downstream 100 bases:

>100_bases
CAGTTATTTATAGTACAATATTATGATCTTTTTGATCTTGTAGTGCTTGTTTGGAGTTAAAGTAAGCAAATTCTTTAATG
CGTGACTGTGATATTGGATC

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLYRLKLLLSGKNSKKERVRAKLEIDISIVFIMLGLLTFGWVMVTSASMIVALDDYNNPYFYSIRQGFFAIIAIFLFLLA
LLVPTKNYEKNYNAFFFVMLIVLVAVLVPGIGKSVNGARRWIPLLIINIQVAELAKLLAIIFFSGYIAENLKKMANFKEG
ILRPITLLGCIAILLLMQPDFGSTVVISICVMGMLFVAGNKVRWYGLLLGTMVMMAAMLVIISPYRMHRITGFLHPWENA
NGSGYQLVQALIGFGRGGWFGDGLGNGIQKQFFLPEARTDFITSVIAEELGVVGLMVLLAVYLFIVFRAMSIAKMAFELN
RYYQAFLAYGVGFWIAFQVFVNIGVNTGLLPTKGLTLPLISYGGSSLLIMCYTLGVLVRVDFENKLLADTINPRYIYKKV
K

Sequences:

>Translated_401_residues
MLYRLKLLLSGKNSKKERVRAKLEIDISIVFIMLGLLTFGWVMVTSASMIVALDDYNNPYFYSIRQGFFAIIAIFLFLLA
LLVPTKNYEKNYNAFFFVMLIVLVAVLVPGIGKSVNGARRWIPLLIINIQVAELAKLLAIIFFSGYIAENLKKMANFKEG
ILRPITLLGCIAILLLMQPDFGSTVVISICVMGMLFVAGNKVRWYGLLLGTMVMMAAMLVIISPYRMHRITGFLHPWENA
NGSGYQLVQALIGFGRGGWFGDGLGNGIQKQFFLPEARTDFITSVIAEELGVVGLMVLLAVYLFIVFRAMSIAKMAFELN
RYYQAFLAYGVGFWIAFQVFVNIGVNTGLLPTKGLTLPLISYGGSSLLIMCYTLGVLVRVDFENKLLADTINPRYIYKKV
K
>Mature_401_residues
MLYRLKLLLSGKNSKKERVRAKLEIDISIVFIMLGLLTFGWVMVTSASMIVALDDYNNPYFYSIRQGFFAIIAIFLFLLA
LLVPTKNYEKNYNAFFFVMLIVLVAVLVPGIGKSVNGARRWIPLLIINIQVAELAKLLAIIFFSGYIAENLKKMANFKEG
ILRPITLLGCIAILLLMQPDFGSTVVISICVMGMLFVAGNKVRWYGLLLGTMVMMAAMLVIISPYRMHRITGFLHPWENA
NGSGYQLVQALIGFGRGGWFGDGLGNGIQKQFFLPEARTDFITSVIAEELGVVGLMVLLAVYLFIVFRAMSIAKMAFELN
RYYQAFLAYGVGFWIAFQVFVNIGVNTGLLPTKGLTLPLISYGGSSLLIMCYTLGVLVRVDFENKLLADTINPRYIYKKV
K

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=374, Percent_Identity=41.7112299465241, Blast_Score=300, Evalue=8e-83,
Organism=Escherichia coli, GI1786853, Length=315, Percent_Identity=32.3809523809524, Blast_Score=136, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44834; Mature: 44834

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYRLKLLLSGKNSKKERVRAKLEIDISIVFIMLGLLTFGWVMVTSASMIVALDDYNNPY
CCEEEEEEECCCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCE
FYSIRQGFFAIIAIFLFLLALLVPTKNYEKNYNAFFFVMLIVLVAVLVPGIGKSVNGARR
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHH
WIPLLIINIQVAELAKLLAIIFFSGYIAENLKKMANFKEGILRPITLLGCIAILLLMQPD
EEEHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGSTVVISICVMGMLFVAGNKVRWYGLLLGTMVMMAAMLVIISPYRMHRITGFLHPWENA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
NGSGYQLVQALIGFGRGGWFGDGLGNGIQKQFFLPEARTDFITSVIAEELGVVGLMVLLA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYLFIVFRAMSIAKMAFELNRYYQAFLAYGVGFWIAFQVFVNIGVNTGLLPTKGLTLPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHH
SYGGSSLLIMCYTLGVLVRVDFENKLLADTINPRYIYKKVK
HCCCCHHHHHHHHHHHHEEECCCCCHHHHCCCCHHHEEECC
>Mature Secondary Structure
MLYRLKLLLSGKNSKKERVRAKLEIDISIVFIMLGLLTFGWVMVTSASMIVALDDYNNPY
CCEEEEEEECCCCCHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCE
FYSIRQGFFAIIAIFLFLLALLVPTKNYEKNYNAFFFVMLIVLVAVLVPGIGKSVNGARR
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHH
WIPLLIINIQVAELAKLLAIIFFSGYIAENLKKMANFKEGILRPITLLGCIAILLLMQPD
EEEHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGSTVVISICVMGMLFVAGNKVRWYGLLLGTMVMMAAMLVIISPYRMHRITGFLHPWENA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
NGSGYQLVQALIGFGRGGWFGDGLGNGIQKQFFLPEARTDFITSVIAEELGVVGLMVLLA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYLFIVFRAMSIAKMAFELNRYYQAFLAYGVGFWIAFQVFVNIGVNTGLLPTKGLTLPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHH
SYGGSSLLIMCYTLGVLVRVDFENKLLADTINPRYIYKKVK
HCCCCHHHHHHHHHHHHEEECCCCCHHHHCCCCHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]