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The map label for this gene is lptD [H]

Identifier: 134302455

GI number: 134302455

Start: 1506057

End: 1508663

Strand: Reverse

Name: lptD [H]

Synonym: FTW_1603

Alternate gene names: 134302455

Gene position: 1508663-1506057 (Counterclockwise)

Preceding gene: 134302457

Following gene: 134302454

Centisome position: 79.47

GC content: 33.29

Gene sequence:

>2607_bases
ATGTTAAAGGGGATTCATAAGTATCTATTGATGTGTTTTGGTACTGTATTGTTTACAGTGCAAGCCAATGCTGCACGGAT
AATGAGCAATAATCCTATTAAAGAAGATTGGCAATGTAAGGTAGTTGATGGTGAGTGGAGTTGTAAACGAGCAAAGAAAC
CAAAAAGTGTCTTTGATAAAAAGCTTACTAAAACTGAAAAAGAAAAAGCTCTTGCTGATGATCTGGCATGGGTCAAGAAA
CCATCATATTTTGTTGGTGGATACTATAGCAATGATAATCAGTTTACCAAAGCTTTGTGTGAGTCTAAAAAGACAGATCT
TAGTTATGAGAAGTCTGAGTTTGACAATTATGGTACATTAATAGCGTCAGGAAATGTCCAGGTGCTACAATGTGATCAGG
AATTGTATGGTAATAATGCAATAATAAATTTAAATAGTAATAATAGTGCTATAAGATCATTAGTGATGGCTGGAGATGTA
ATCGTTAAGCAACCATCGACAGGTATAGTCATCCGTACTACAGAGTTAGATGCTGATATGAATAATGGTACTTATAGTAC
TGGTGAAGCATATTTTAGATTGGCGCGTGAAATGCCAAAAACTAGAATATATGATAAAGAACATTTTAGTGGCTACTTGC
GTGGTTATGCTAAAACATTCAAAAAAGAGTCATCAGGAGATATAGTACTTTCTGATGGATATATTACTTCTGGTGATCCG
TATGATAATGCTTGGAAGATTACTGGTAATAATATAGATATTGATACCAACACTCATATGGCGTATGTCAAAAATGGTTA
TTTTGAGATTCAGGATATTCCAGTAATGTATATACCATATTTTTCACATCCAATAGATGATAGAAGAAGATCTGGTTTCT
TATATCCAGGTTTTGTACAAAATGCTAACTCTGGTATTGGGATATCTGTACCTTATTATTTTAACCTTGCGCCTAATTAT
GATTTGATGTTACAAAGTGTTATATGGTCTCAAAGAGGTATCATGGAAAATGGTACTTTCCGTTACATGACTAAATATTT
CCAGGGTCAATTTGAGGGTTCATTAGTACCTTATGATTTTAAAGAAGGAAAAATGCGCGGCTCTTTTACTTTGTCAACTA
CAGGTCAGTATGAAAATATAAACACAAATTTTAAGTATGAATATGTTAGTGACCAAAACTATTATAATGATTTCTCAACA
GGAAATGTTAATTTAGTTACTAAGACATTACTGGATAGAGAATTCGATCTAACTTACACTAATGACTATGTTGATTCTGG
GTTAACAGTATTAGACTATGGTGTAGTAAACCCTTTATTAACCGTTGATAACACACCTTATGCTAAGCTACCTGAAGTTA
AGTTAAATCTTACGTCGGATGGTTATACACCAGATTATTTGACTTTAAGTGCTCAAACTCTTAATACATTTTTTTATAAA
ACTGCTGGGCCAGCTAATACTAATCCTGGTGCTCCTCAAGGAACAAATGTTAATGCATTTAGAGCTTATGAATCTCCAAA
AATAGCATTCAACTTTAATAAAACATGGGGGTATCTAAATCCTTCATTAGAGGTGCCTATTCGTTATTATCAACTAAAAA
ATAGCCCTACAGATACGATACAGTTTGCTAATAGTAGTGTTACTAGTGTATTGCCTATATTTAATATTGACGCTGGGGCA
TATTTTGATAAAGATTATACTAATGAAAATGGGACGTATACATCAACCTTACATCCTAGACTATTCTATACTTACATACC
GTACCAAGATCAAACAAATATACCATTATTTGATACAAGTTTACAAAATGAACAATATATGCAGATGTTTCAAGTAAATA
GATTTACTGGTTATGATAGAATCAACAATGCTAATCAGCTAACATATGCGATAGAAGCTTCAACAACTAATCAAGATAAT
GGTACTACTCTAGCGTCTGCTAAAATTGGTCAGATGGCTTATTTTGCTGATAGGAAAGTTAATTTGTGTCAAGGAAATTC
TGCTTGTCCGAATCCGGGTTTAATGGATCCTTTTTCAACAGATACTTTCTCTCCAATTATGAGCTCATTTGAGTTTCAAG
TAATGAAAAATATTTACTTATCAGCTCAAGTGAATTATAGGGTTAAGCAACAAAACGTTGACTATCAAGTCTATCAATTG
TCATATAAGGATGAAAATGAGAATATTTTTAACGTTTCATATAATAATATTGCAAATAACTGGAACTCATTGACTCAACA
GCAAATAGCAGAAGGTGCTAAGCCTCAACCACAAGAAACTATTACTCTTTCTACAGTGTTAAATATTACTGATCATTGGG
GTATTGCAGCGCTATGGAACTATAATTTCCAGCAAAAACAAATAGCTAATATATTTGCAGGGCTGCAATACAATGCCAAA
TCTTGGGCGGTTAGAGCATTATGGCAGAAGACCGCGTATACTAACCAAGATCCTAATAATCCAACATTACTTGGCCCACT
AGTTAATACTTATATGTTTGAATTTGAACTAAAAGGTCTAGGAGGTATTGGCAATACTAGTGATATATCTTCACGTTTAC
AACAAATAAATGGTTATCAAGTAGGAGAGTGGGGAAACGGTATATAA

Upstream 100 bases:

>100_bases
ATCTAGAGTTTAAATTAGAATGGAAATATTTCTCAAATATATATATAATATCACGGTTATTTTAAAAAACTCAATAAATT
AAGGCTTTCAAAGGTCAATT

Downstream 100 bases:

>100_bases
TGAAGAAGCTAATAACAATCTTTTTGTTGATGCTAATGTTAAATAATGCTTATTCAGATATCTCTTCATCTATGTTTCAA
AATGCTTTTAACTCGGGTAT

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 868; Mature: 868

Protein sequence:

>868_residues
MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDKKLTKTEKEKALADDLAWVKK
PSYFVGGYYSNDNQFTKALCESKKTDLSYEKSEFDNYGTLIASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDV
IVKQPSTGIVIRTTELDADMNNGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDP
YDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFVQNANSGIGISVPYYFNLAPNY
DLMLQSVIWSQRGIMENGTFRYMTKYFQGQFEGSLVPYDFKEGKMRGSFTLSTTGQYENINTNFKYEYVSDQNYYNDFST
GNVNLVTKTLLDREFDLTYTNDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYK
TAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLNPSLEVPIRYYQLKNSPTDTIQFANSSVTSVLPIFNIDAGA
YFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDN
GTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQL
SYKDENENIFNVSYNNIANNWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAK
SWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGLGGIGNTSDISSRLQQINGYQVGEWGNGI

Sequences:

>Translated_868_residues
MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDKKLTKTEKEKALADDLAWVKK
PSYFVGGYYSNDNQFTKALCESKKTDLSYEKSEFDNYGTLIASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDV
IVKQPSTGIVIRTTELDADMNNGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDP
YDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFVQNANSGIGISVPYYFNLAPNY
DLMLQSVIWSQRGIMENGTFRYMTKYFQGQFEGSLVPYDFKEGKMRGSFTLSTTGQYENINTNFKYEYVSDQNYYNDFST
GNVNLVTKTLLDREFDLTYTNDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYK
TAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLNPSLEVPIRYYQLKNSPTDTIQFANSSVTSVLPIFNIDAGA
YFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDN
GTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQL
SYKDENENIFNVSYNNIANNWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAK
SWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGLGGIGNTSDISSRLQQINGYQVGEWGNGI
>Mature_868_residues
MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDKKLTKTEKEKALADDLAWVKK
PSYFVGGYYSNDNQFTKALCESKKTDLSYEKSEFDNYGTLIASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDV
IVKQPSTGIVIRTTELDADMNNGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDP
YDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFVQNANSGIGISVPYYFNLAPNY
DLMLQSVIWSQRGIMENGTFRYMTKYFQGQFEGSLVPYDFKEGKMRGSFTLSTTGQYENINTNFKYEYVSDQNYYNDFST
GNVNLVTKTLLDREFDLTYTNDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYK
TAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLNPSLEVPIRYYQLKNSPTDTIQFANSSVTSVLPIFNIDAGA
YFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTSLQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDN
GTTLASAKIGQMAYFADRKVNLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQL
SYKDENENIFNVSYNNIANNWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWNYNFQQKQIANIFAGLQYNAK
SWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGLGGIGNTSDISSRLQQINGYQVGEWGNGI

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=663, Percent_Identity=23.8310708898944, Blast_Score=169, Evalue=8e-43,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 98464; Mature: 98464

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00214 FABP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDK
CCCHHHHHHHHHHHHHHEEEECCCEEEECCCCCCCCCEEEEECCCCCCHHCCCCHHHHHH
KLTKTEKEKALADDLAWVKKPSYFVGGYYSNDNQFTKALCESKKTDLSYEKSEFDNYGTL
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCHHCCCCCCEE
IASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDVIVKQPSTGIVIRTTELDADM
EECCCEEEEEECHHHHCCCEEEEECCCCHHHHHHHHHCCEEEECCCCCEEEEEEEECCCC
NNGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDP
CCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCEEECCCC
YDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFVQ
CCCEEEEECCEEEECCCCEEEEEECCEEEEECCCEEEEECCCCCCCHHHHCCCCCCCHHC
NANSGIGISVPYYFNLAPNYDLMLQSVIWSQRGIMENGTFRYMTKYFQGQFEGSLVPYDF
CCCCCCEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
KEGKMRGSFTLSTTGQYENINTNFKYEYVSDQNYYNDFSTGNVNLVTKTLLDREFDLTYT
CCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHCCCCCEEEC
NDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYK
CHHHHCCCEEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEHHHHEEEEEE
TAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLNPSLEVPIRYYQLKNSPTDTI
CCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCEECCCEECCEEEEEECCCCCCEE
QFANSSVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTS
EECCCCCCEEEEEEECCCCCEECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEECC
LQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRKV
CCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEHHHCCEEEECCCCE
NLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQL
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEEEEEECCCCCEEEEEE
SYKDENENIFNVSYNNIANNWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWN
EEECCCCCEEEEEHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEEE
YNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGL
CCCCHHHHHHHHHCCEECCHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHEEEEEEEEECC
GGIGNTSDISSRLQQINGYQVGEWGNGI
CCCCCHHHHHHHHHHHCCEEECCCCCCC
>Mature Secondary Structure
MLKGIHKYLLMCFGTVLFTVQANAARIMSNNPIKEDWQCKVVDGEWSCKRAKKPKSVFDK
CCCHHHHHHHHHHHHHHEEEECCCEEEECCCCCCCCCEEEEECCCCCCHHCCCCHHHHHH
KLTKTEKEKALADDLAWVKKPSYFVGGYYSNDNQFTKALCESKKTDLSYEKSEFDNYGTL
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCHHCCCCCCEE
IASGNVQVLQCDQELYGNNAIINLNSNNSAIRSLVMAGDVIVKQPSTGIVIRTTELDADM
EECCCEEEEEECHHHHCCCEEEEECCCCHHHHHHHHHCCEEEECCCCCEEEEEEEECCCC
NNGTYSTGEAYFRLAREMPKTRIYDKEHFSGYLRGYAKTFKKESSGDIVLSDGYITSGDP
CCCCCCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCEEECCCC
YDNAWKITGNNIDIDTNTHMAYVKNGYFEIQDIPVMYIPYFSHPIDDRRRSGFLYPGFVQ
CCCEEEEECCEEEECCCCEEEEEECCEEEEECCCEEEEECCCCCCCHHHHCCCCCCCHHC
NANSGIGISVPYYFNLAPNYDLMLQSVIWSQRGIMENGTFRYMTKYFQGQFEGSLVPYDF
CCCCCCEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCC
KEGKMRGSFTLSTTGQYENINTNFKYEYVSDQNYYNDFSTGNVNLVTKTLLDREFDLTYT
CCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHCCCCCEEEC
NDYVDSGLTVLDYGVVNPLLTVDNTPYAKLPEVKLNLTSDGYTPDYLTLSAQTLNTFFYK
CHHHHCCCEEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEHHHHEEEEEE
TAGPANTNPGAPQGTNVNAFRAYESPKIAFNFNKTWGYLNPSLEVPIRYYQLKNSPTDTI
CCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCEECCCEECCEEEEEECCCCCCEE
QFANSSVTSVLPIFNIDAGAYFDKDYTNENGTYTSTLHPRLFYTYIPYQDQTNIPLFDTS
EECCCCCCEEEEEEECCCCCEECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEECC
LQNEQYMQMFQVNRFTGYDRINNANQLTYAIEASTTNQDNGTTLASAKIGQMAYFADRKV
CCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEEHHHCCEEEECCCCE
NLCQGNSACPNPGLMDPFSTDTFSPIMSSFEFQVMKNIYLSAQVNYRVKQQNVDYQVYQL
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEEEEEECCCCCEEEEEE
SYKDENENIFNVSYNNIANNWNSLTQQQIAEGAKPQPQETITLSTVLNITDHWGIAALWN
EEECCCCCEEEEEHHHHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCEEEEEE
YNFQQKQIANIFAGLQYNAKSWAVRALWQKTAYTNQDPNNPTLLGPLVNTYMFEFELKGL
CCCCHHHHHHHHHCCEECCHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHEEEEEEEEECC
GGIGNTSDISSRLQQINGYQVGEWGNGI
CCCCCHHHHHHHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA