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The map label for this gene is trxB [H]

Identifier: 134302434

GI number: 134302434

Start: 1482537

End: 1483487

Strand: Direct

Name: trxB [H]

Synonym: FTW_1580

Alternate gene names: 134302434

Gene position: 1482537-1483487 (Clockwise)

Preceding gene: 134302433

Following gene: 134302435

Centisome position: 78.09

GC content: 36.91

Gene sequence:

>951_bases
ATGGCAAATCATCATAAACTAATAATTTTAGGATCTGGGCCTGCTGGCTATACTGCAGCAATATATGCAGCACGTGCAAA
CTTAAAGCCAGTAATTATCACTGGTATGCAACCAGGAGGTCAACTTACGACTACTACCGATGTAGATAACTGGCCTGGTG
AGCCTGATGGTATCATGGGTCCTGAGCTTATGGAAAAACTACAAAAACAAGCAGAAAGATTCGATACACAAATAGTCTAT
GACACTATCAATGCTGTAGATTTACAAAATAAACCTTTTAAACTAGTTGGTGAAGTTGAGCAATATACATGTGATACTCT
AATTATAGCAACTGGTGCTACTGCTAAATATCTAGGTTTAGAGTCAGAAGAGAAGTTTATGGGTAAAGGTGTCTCTGCTT
GTGCTACTTGTGATGGCTTCTTTTACAAAAATAAAGACGTTGCAGTAGTTGGTGGTGGCAACACTGCTGTTGAAGAAGCA
TTATTTTTATCCAATATTGCTAAATCTGTAACTTTAATCCACCGTAGAGATACATTAAGGTCTGAAAAAATTCTTATCGA
CAAGCTAATGGAAAAAGCTCAACATGGTAATATAAATATCATTTGGAACACTACTTTAGAAGAAGTTCTTGGCGATGATA
TGGGAGTTAATGCTCTGCGTATCAAAAATATCAAAACTAATGAAGAGTCTCAAATGGATGTCGCTGGTGTTTTTATTGCT
ATTGGCCATACACCAAATACTAGTATTTTTGCTGGTCAGCTTGAAATGGAAAATGGTTATATTAAGGTGAAATCAGGTCT
AGCTGGCGATGCTACTCAAACAAATATCAAAGGGGTATTTGCAGCTGGTGATGTAGCTGATCATGTTTATAAACAAGCAG
TAACATCTGCAGGTACTGGCTGTATGGCTGCACTAGATGCTGAGAAGTATTTAGATAATTTAGATCAATAA

Upstream 100 bases:

>100_bases
TGTACCTAATATATACTATATAAACGTATTGAAAGTTTACTTAAATTAGCACTATGCTATAATTTGCTCTACATATTTAT
TCAAAAATTTTTTAAAAAAA

Downstream 100 bases:

>100_bases
AATATAAACCCTCACTTAATAAATTAAATATTAGCCATAATATAATTTTCAATTAATAAAATTTTATCTAAAATATAAAG
TACGGCAATTTATTTAACTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIMGPELMEKLQKQAERFDTQIVY
DTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEA
LFLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMDVAGVFIA
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ

Sequences:

>Translated_316_residues
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIMGPELMEKLQKQAERFDTQIVY
DTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEA
LFLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMDVAGVFIA
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ
>Mature_315_residues
ANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIMGPELMEKLQKQAERFDTQIVYD
TINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEAL
FLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMDVAGVFIAI
GHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=312, Percent_Identity=67.948717948718, Blast_Score=463, Evalue=1e-132,
Organism=Escherichia coli, GI87081763, Length=300, Percent_Identity=32.6666666666667, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=50.3086419753086, Blast_Score=309, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6321898, Length=321, Percent_Identity=48.5981308411215, Blast_Score=298, Evalue=5e-82,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34008; Mature: 33877

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIMG
CCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
PELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGL
HHHHHHHHHHHHHHCCEEEEECCCEEECCCCCHHEEECHHHHCCCEEEEECCCCEEEECC
ESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEALFLSNIAKSVTLIHRRDTLR
CCHHHHHCCCCCHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEHHHHHHH
SEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMDVAGVFIA
HHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEEE
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTG
ECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCC
CMAALDAEKYLDNLDQ
CEEECCHHHHHHHCCC
>Mature Secondary Structure 
ANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVDNWPGEPDGIMG
CCCEEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCEEEECCCCCCCCCCCCCCC
PELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGL
HHHHHHHHHHHHHHCCEEEEECCCEEECCCCCHHEEECHHHHCCCEEEEECCCCEEEECC
ESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEALFLSNIAKSVTLIHRRDTLR
CCHHHHHCCCCCHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEHHHHHHH
SEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMDVAGVFIA
HHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEEEEE
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTG
ECCCCCCCEEEEEEEECCCEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCC
CMAALDAEKYLDNLDQ
CEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]