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The map label for this gene is gph [C]

Identifier: 134302432

GI number: 134302432

Start: 1480526

End: 1481185

Strand: Direct

Name: gph [C]

Synonym: FTW_1578

Alternate gene names: 134302432

Gene position: 1480526-1481185 (Clockwise)

Preceding gene: 134302431

Following gene: 134302433

Centisome position: 77.98

GC content: 31.67

Gene sequence:

>660_bases
ATGATAAAAAATATATTTTTTGACTTAGATGGTACGCTTGTAAATACTGTAGGTGATCTAACAGTGGCTACAAATACTAT
GCGTAAACATTTTGGACTTAATCCTGTATCTGAAGATGTTTTGGCTAATATTATTGGCAAAGGCTACCCCACTACTGTTA
GAAAAGTCCTGGCACTAGATTTTGATGATAAAGATTATATCGAGTCTATAGCTGATGAAGGTGTTAAAATAGTCAGTCAA
ACATACAAAACTCTAAATAGTGCTAATAGCAAGGTATATCCTAATATTTTTAAAACATTAGATTTTTTGAAACAACAAAA
TATCAAAATGGCTGTTGTCACAAACAAACATGAAGAAGATGCTATACAATCCCTAACTCACTTAGGTTTGGTTGATTATT
TTGAAGTGATAGTTGGTGGAGATTCTACAGCTAGCTACAAACCCTATCCTGAACCACTATTATTCGCAATGAATAAATTG
AATGCTAAGCCAGAAGAAAGCCTAATGGTTGGGGATTCTATTAATGATTTCTTATGTGCACAAGGTGCTAATATAAAGAT
AGTAATAGTCAGTTATGGCTATCATAATGGTATTGATCTTAAGTCCTTAGAGAGCTTTGCTTATATTGATGATTTTTCTA
CTATTAAAAATTTAATTTAG

Upstream 100 bases:

>100_bases
TTAAGTAAATTTATAGTAGATAGTTTCTCAAAATTCAAAAGTTAGAAACATTGCTTAAATTTAGATATAATCTTGACTAA
AAAAGTTGATTTCTTATACG

Downstream 100 bases:

>100_bases
ATAAAATAAAAACTGTTAACCCAAATCTAAGGAAATTTACTAATGAGAATTTTATTTACAATTTTAGCTTTTTTTGGATA
CAGTTATGGGTTAGCACATG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MIKNIFFDLDGTLVNTVGDLTVATNTMRKHFGLNPVSEDVLANIIGKGYPTTVRKVLALDFDDKDYIESIADEGVKIVSQ
TYKTLNSANSKVYPNIFKTLDFLKQQNIKMAVVTNKHEEDAIQSLTHLGLVDYFEVIVGGDSTASYKPYPEPLLFAMNKL
NAKPEESLMVGDSINDFLCAQGANIKIVIVSYGYHNGIDLKSLESFAYIDDFSTIKNLI

Sequences:

>Translated_219_residues
MIKNIFFDLDGTLVNTVGDLTVATNTMRKHFGLNPVSEDVLANIIGKGYPTTVRKVLALDFDDKDYIESIADEGVKIVSQ
TYKTLNSANSKVYPNIFKTLDFLKQQNIKMAVVTNKHEEDAIQSLTHLGLVDYFEVIVGGDSTASYKPYPEPLLFAMNKL
NAKPEESLMVGDSINDFLCAQGANIKIVIVSYGYHNGIDLKSLESFAYIDDFSTIKNLI
>Mature_219_residues
MIKNIFFDLDGTLVNTVGDLTVATNTMRKHFGLNPVSEDVLANIIGKGYPTTVRKVLALDFDDKDYIESIADEGVKIVSQ
TYKTLNSANSKVYPNIFKTLDFLKQQNIKMAVVTNKHEEDAIQSLTHLGLVDYFEVIVGGDSTASYKPYPEPLLFAMNKL
NAKPEESLMVGDSINDFLCAQGANIKIVIVSYGYHNGIDLKSLESFAYIDDFSTIKNLI

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=216, Percent_Identity=28.7037037037037, Blast_Score=97, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24316; Mature: 24316

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01228 COF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNIFFDLDGTLVNTVGDLTVATNTMRKHFGLNPVSEDVLANIIGKGYPTTVRKVLALD
CCCCEEEECCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHCC
FDDKDYIESIADEGVKIVSQTYKTLNSANSKVYPNIFKTLDFLKQQNIKMAVVTNKHEED
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHH
AIQSLTHLGLVDYFEVIVGGDSTASYKPYPEPLLFAMNKLNAKPEESLMVGDSINDFLCA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHC
QGANIKIVIVSYGYHNGIDLKSLESFAYIDDFSTIKNLI
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKNIFFDLDGTLVNTVGDLTVATNTMRKHFGLNPVSEDVLANIIGKGYPTTVRKVLALD
CCCCEEEECCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHCC
FDDKDYIESIADEGVKIVSQTYKTLNSANSKVYPNIFKTLDFLKQQNIKMAVVTNKHEED
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHH
AIQSLTHLGLVDYFEVIVGGDSTASYKPYPEPLLFAMNKLNAKPEESLMVGDSINDFLCA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCHHHHC
QGANIKIVIVSYGYHNGIDLKSLESFAYIDDFSTIKNLI
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA