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The map label for this gene is glpT [H]

Identifier: 134302385

GI number: 134302385

Start: 1418726

End: 1420042

Strand: Direct

Name: glpT [H]

Synonym: FTW_1513

Alternate gene names: 134302385

Gene position: 1418726-1420042 (Clockwise)

Preceding gene: 134302384

Following gene: 134302386

Centisome position: 74.73

GC content: 36.29

Gene sequence:

>1317_bases
ATGAATTTCCTTAAACCTGCAAAAGCTCTGCCTTTACTAGCTAAAGAGCAAATTCAAAAAGCATACCCTCACTGGCGCCT
AAGAATGTTCTTAGTGGCTTATATAGGTTACTTTATATACTATTTCGGTCGTAGTAGTTTTGATGTCTCAAAACAATATA
TTACAACCCTAACTCCAGATGAGCTTGGATTAATTGGAGCTGGTCTAGGTATTGCCTATGGTATAAGTAAGTTTCTAATG
GGAAATATCTCTGATAGAAGTAATGCCAAAGTATTTTTAGCTATCGGATTATTTATCACAGGACTTATAAACCTTCTATT
GCCAAGCTTATTATCATTAGGCGTACTTGTAATGTTTATCGCAATGCTTGTAAACGGTTGGGTGCAAGGTATGGGCTGGC
CAGCATGTGCTCGTATAATGACACACTGGTTTTGTGCTAATGAGCGTGGTACTAAAATGGGTATTTGGAATACTGCTCAT
AACGTTGGAGCAGGTTTTTTAGCTATTGCTGTTGTGCCTATTGGATTACTGCTATTTCATGATGACTGGCATGGTCTTTT
TTATGTTGCAGGAGCAATGTGTATTTTTGTATCAATTTTAGTCCTGATATTTGGTGCTGACACTCCTCAATCAGTTGGCT
TACCAGCAATAGAAGTATATAAAGGTTATACTACTGCCGAAGCTCATCATGAACAAGAGTTTTCAGCTAAAGAAATCTTT
TTAAAATATGTATTAAATAATAAGTGGGTTTGGTTAATTGCCATAGCGAATGCATTTGTTTATTGTGCTAGGTATGGTCT
TCTTAGCTGGTCAACTTATTATCTTGTTAATGTAAAGCATATGTCTACCACTACCGGACTTTTAGGTTTTGCATTATTTG
AATTACCAGCAATTCCAGGAACTATAATAATTGGTTGGATAACAGATAAGTATTTTGGTAGTCGTAGAGCCCCAATGGGT
GTAATATGTATGCTTTTATTTATTTGTGCTTTATTTGTATATTGGTATAGTGATACTGCTTGGGTATTATTACTTTCATT
ATCTGCGATGGGAGTACTAATATATGGGCCTGTCGCTTTGATAGGGATATTGGCTTTGGACTTAGTACCTAAAAAAGCTG
GTGGGACTGCAGCTGGGTTTACAGGATTATTTGGCTATTTTTTAGGTACAGTTGGAGCACAAGCTGTGATTGGTATTATT
GCCACAATGCTAGGATGGGACGCTGTATTTATATTTTTATTAGGTTCATGTATAATTGCCATAGCACTTCTAGCTGTTTG
CTGGAATCTTAGTTATAATCAAGCTTTCAGTGATTAA

Upstream 100 bases:

>100_bases
AACAAATAATCTAGATATAAACGCTTAATCATATTGCTGAATATGAAAAATTAAACTAAACTATCCTACCAATAATGTTT
AAATTAGATTATTTTTAACG

Downstream 100 bases:

>100_bases
TTACTTAGAATATAAATGCCCATAAAATTACTTAAATCATTATTATTATTTTTTATATTATCAGTCTTTATAGCATATCC
ACTATCAGTAAATTCAATAG

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MNFLKPAKALPLLAKEQIQKAYPHWRLRMFLVAYIGYFIYYFGRSSFDVSKQYITTLTPDELGLIGAGLGIAYGISKFLM
GNISDRSNAKVFLAIGLFITGLINLLLPSLLSLGVLVMFIAMLVNGWVQGMGWPACARIMTHWFCANERGTKMGIWNTAH
NVGAGFLAIAVVPIGLLLFHDDWHGLFYVAGAMCIFVSILVLIFGADTPQSVGLPAIEVYKGYTTAEAHHEQEFSAKEIF
LKYVLNNKWVWLIAIANAFVYCARYGLLSWSTYYLVNVKHMSTTTGLLGFALFELPAIPGTIIIGWITDKYFGSRRAPMG
VICMLLFICALFVYWYSDTAWVLLLSLSAMGVLIYGPVALIGILALDLVPKKAGGTAAGFTGLFGYFLGTVGAQAVIGII
ATMLGWDAVFIFLLGSCIIAIALLAVCWNLSYNQAFSD

Sequences:

>Translated_438_residues
MNFLKPAKALPLLAKEQIQKAYPHWRLRMFLVAYIGYFIYYFGRSSFDVSKQYITTLTPDELGLIGAGLGIAYGISKFLM
GNISDRSNAKVFLAIGLFITGLINLLLPSLLSLGVLVMFIAMLVNGWVQGMGWPACARIMTHWFCANERGTKMGIWNTAH
NVGAGFLAIAVVPIGLLLFHDDWHGLFYVAGAMCIFVSILVLIFGADTPQSVGLPAIEVYKGYTTAEAHHEQEFSAKEIF
LKYVLNNKWVWLIAIANAFVYCARYGLLSWSTYYLVNVKHMSTTTGLLGFALFELPAIPGTIIIGWITDKYFGSRRAPMG
VICMLLFICALFVYWYSDTAWVLLLSLSAMGVLIYGPVALIGILALDLVPKKAGGTAAGFTGLFGYFLGTVGAQAVIGII
ATMLGWDAVFIFLLGSCIIAIALLAVCWNLSYNQAFSD
>Mature_438_residues
MNFLKPAKALPLLAKEQIQKAYPHWRLRMFLVAYIGYFIYYFGRSSFDVSKQYITTLTPDELGLIGAGLGIAYGISKFLM
GNISDRSNAKVFLAIGLFITGLINLLLPSLLSLGVLVMFIAMLVNGWVQGMGWPACARIMTHWFCANERGTKMGIWNTAH
NVGAGFLAIAVVPIGLLLFHDDWHGLFYVAGAMCIFVSILVLIFGADTPQSVGLPAIEVYKGYTTAEAHHEQEFSAKEIF
LKYVLNNKWVWLIAIANAFVYCARYGLLSWSTYYLVNVKHMSTTTGLLGFALFELPAIPGTIIIGWITDKYFGSRRAPMG
VICMLLFICALFVYWYSDTAWVLLLSLSAMGVLIYGPVALIGILALDLVPKKAGGTAAGFTGLFGYFLGTVGAQAVIGII
ATMLGWDAVFIFLLGSCIIAIALLAVCWNLSYNQAFSD

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=380, Percent_Identity=25.7894736842105, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4503847, Length=380, Percent_Identity=25.7894736842105, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI256219483, Length=380, Percent_Identity=25.7894736842105, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI256219543, Length=429, Percent_Identity=24.2424242424242, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI256219564, Length=309, Percent_Identity=23.9482200647249, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38093649, Length=398, Percent_Identity=25.3768844221106, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI223717983, Length=398, Percent_Identity=25.3768844221106, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1788573, Length=435, Percent_Identity=42.5287356321839, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI87082310, Length=398, Percent_Identity=34.6733668341709, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI2367259, Length=437, Percent_Identity=32.7231121281465, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1789152, Length=388, Percent_Identity=25.7731958762887, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI2367379, Length=312, Percent_Identity=22.7564102564103, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789515, Length=432, Percent_Identity=22.6851851851852, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564204, Length=381, Percent_Identity=26.7716535433071, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564202, Length=444, Percent_Identity=25.6756756756757, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI133901856, Length=391, Percent_Identity=24.8081841432225, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI133901854, Length=391, Percent_Identity=24.8081841432225, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656866, Length=467, Percent_Identity=20.7708779443255, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550478, Length=467, Percent_Identity=20.7708779443255, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24656861, Length=467, Percent_Identity=20.7708779443255, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48039; Mature: 48039

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MNFLKPAKALPLLAKEQIQKAYPHWRLRMFLVAYIGYFIYYFGRSSFDVSKQYITTLTPD
CCCCCCHHHCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCC
ELGLIGAGLGIAYGISKFLMGNISDRSNAKVFLAIGLFITGLINLLLPSLLSLGVLVMFI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVNGWVQGMGWPACARIMTHWFCANERGTKMGIWNTAHNVGAGFLAIAVVPIGLLLFH
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHCHHHHHHHHHHHHHHHEE
DDWHGLFYVAGAMCIFVSILVLIFGADTPQSVGLPAIEVYKGYTTAEAHHEQEFSAKEIF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
LKYVLNNKWVWLIAIANAFVYCARYGLLSWSTYYLVNVKHMSTTTGLLGFALFELPAIPG
HHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCC
TIIIGWITDKYFGSRRAPMGVICMLLFICALFVYWYSDTAWVLLLSLSAMGVLIYGPVAL
EEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IGILALDLVPKKAGGTAAGFTGLFGYFLGTVGAQAVIGIIATMLGWDAVFIFLLGSCIIA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IALLAVCWNLSYNQAFSD
HHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]